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MAP2K3 抗体

(Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3))
The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq, Jul 2008].
MAP2K3 抗体  (AA 1-170) MAP2K3 抗体  (AA 1-170) MAP2K3 抗体 (AA 1-170) (ABIN6143484)

MAP2K3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

MAP2K3 抗体 MAP2K3 抗体 MAP2K3 抗体 (ABIN7263723)

MAP2K3 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

MAP2K3 抗体 MAP2K3 抗体 MAP2K3 抗体 (ABIN1499403)

MAP2K3 适用: 人, 犬, 猴 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 5C7 unconjugated

MAP2K3 抗体 by 适用

Find MAP2K3 抗体 for a variety of species such as anti-Human MAP2K3, anti-Mouse MAP2K3, anti-Rat MAP2K3. The species listed below are among those available. Click on a link to go to the corresponding products.

MAP2K3 抗体 by 应用范围

Find MAP2K3 抗体 validated for a specific application such as WB, ELISA, IF (cc), IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

MAP2K3 抗体 by 抗体来源

Find MAP2K3 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

MAP2K3 抗体 by 抗原表位

Find MAP2K3 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

MAP2K3 抗体 by 克隆形成能力

Find available monoclonal or polyclonal MAP2K3 抗体. Click on a link to go to the corresponding products.

MAP2K3 抗体 by 克隆

Find MAP2K3 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

MAP2K3 抗体 by 标记

Find MAP2K3 抗体 with a specific conjugate such as Biotin, FITC, Alexa Fluor 488. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular MAP2K3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (1)
  • (7)
Cat. No. ABIN6143484
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (6)
Cat. No. ABIN7263723
Quantity 200 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey
Application WB, IHC, IF, IHC (p)
Validations
  • (9)
Cat. No. ABIN1499403
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse
Application WB, IHC, IF, IHC (p)
Validations
  • (9)
Cat. No. ABIN1499401
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, ICC, FACS
Validations
  • (9)
Cat. No. ABIN5542528
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IP
Validations
  • (5)
Cat. No. ABIN562427
Quantity 100 μg
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IF, IHC (p)
Validations
  • (5)
Cat. No. ABIN1499400
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (4)
Cat. No. ABIN7138459
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (3)
Cat. No. ABIN6243255
Quantity 400 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN1499399
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6256178
Quantity 100 μL
Datasheet Datasheet
Reactivity Dog, Human, Monkey, Mouse, Rat
Application WB, IHC, IF, IHC (p)
Validations
  • (4)
Cat. No. ABIN1499398
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (4)
Cat. No. ABIN1682965
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (2)
  • (4)
Cat. No. ABIN3043874
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, IF
Validations
  • (3)
Cat. No. ABIN7150707
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our MAP2K3 抗体

Cheng, Wang, Wang, Wang, Du, Lou: "Silencing Ras-Related C3 Botulinum Toxin Substrate 1 Inhibits Growth and Migration of Hypopharyngeal Squamous Cell Carcinoma via the P38 Mitogen-Activated Protein Kinase Signaling Pathway." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 24, pp. 768-781, (2018) (PubMed).

Ma, Chen, Zhang, Ma, Yang, Zhang, Li, Xiao, Wang: "MAPK kinase 10.2 promotes disease resistance and drought tolerance by activating different MAPKs in rice." in: The Plant journal : for cell and molecular biology, Vol. 92, Issue 4, pp. 557-570, (2018) (PubMed).

Xu, Zhang, Wei, Jia, Ge, Zhang, Liu: "MicroRNA-21 promotes hepatocellular carcinoma HepG2 cell proliferation through repression of mitogen-activated protein kinase-kinase 3." in: BMC cancer, Vol. 13, pp. 469, (2013) (PubMed).

Demuth, Reavie, Rennert, Nakada, Nakada, Hoelzinger, Beaudry, Henrichs, Anderson, Berens: "MAP-ing glioma invasion: mitogen-activated protein kinase kinase 3 and p38 drive glioma invasion and progression and predict patient survival." in: Molecular cancer therapeutics, Vol. 6, Issue 4, pp. 1212-22, (2007) (PubMed).

Prickett, Brautigan: "Cytokine activation of p38 mitogen-activated protein kinase and apoptosis is opposed by alpha-4 targeting of protein phosphatase 2A for site-specific dephosphorylation of MEK3." in: Molecular and cellular biology, Vol. 27, Issue 12, pp. 4217-27, (2007) (PubMed).

Edlund, Bu, Schuster, Aspenström, Heuchel, Heldin, ten Dijke, Heldin, Landström et al.: "Transforming growth factor-beta1 (TGF-beta)-induced apoptosis of prostate cancer cells involves Smad7-dependent activation of p38 by TGF-beta-activated kinase 1 and mitogen-activated protein kinase ..." in: Molecular biology of the cell, Vol. 14, Issue 2, pp. 529-44, (2003) (PubMed).

Yustein, Xia, Kahlenburg, Robinson, Templeton, Kung: "Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38." in: Oncogene, Vol. 22, Issue 40, pp. 6129-41, (2003) (PubMed).

Wang, Chen, Liao, Deng, Zhou, Huang, Sun: "Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence." in: Molecular and cellular biology, Vol. 22, Issue 10, pp. 3389-403, (2002) (PubMed).

Aliases for MAP2K3 抗体

mitogen-activated protein kinase kinase 3 (MAP2K3) 抗体
mitogen-activated protein kinase kinase 3 (Map2k3) 抗体
mitogen activated protein kinase kinase 3 (Map2k3) 抗体
MAP kinase activator XMEK3 (map2k3) 抗体
AW212142 抗体
MAPKK3 抗体
MEK3 抗体
MKK3 抗体
Mkk3 抗体
mMKK3b 抗体
PRKMK3 抗体
Prkmk3 抗体
SAPKK-2 抗体
SAPKK2 抗体
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