MAP2K1 (MAP2K1) ELISA试剂盒产品概述

Full name:
Mitogen-Activated Protein Kinase Kinase 1 ELISA试剂盒 (MAP2K1)
在www.antibodies-online.cn可供32 Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) ELISA试剂盒的13不同的供货商。 再加上,我们可以发MAP2K1 抗体 (646)MAP2K1 蛋白 (26)和数多这个蛋白质的别的产品。 总共744 MAP2K1产品已列进来了。
别名:
ATMEK1, CFC3, F20B18.180, F20B18_180, MAP kinase/ ERK kinase 1, MAPKK1, MEK, mek-2, MEK1, MEKK1, MITOGEN ACTIVATED PROTEIN KINASE KINASE, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1, MKK1, NMAPKK, Prkmk1, si:ch211-242m18.2, wu:fj56a12, wu:fj61b01, zgc:56557

引用最多的MAP2K1 ELISA试剂盒

  1. Rat (Rattus) MAP2K1 ELISA Kit for Sandwich ELISA - ABIN433773 : Du, Wang, Wang: Role of RhoA/MERK1/ERK1/2/iNOS signaling in ocular ischemic syndrome. in Graefe's archive for clinical and experimental ophthalmology 2016 (PubMed)

适于 MAP2K1 相互作用对的更多 ELISA 试剂盒

Human Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Data show that combined therapy using HER2 (显示 ERBB2 ELISA试剂盒) inhibitor and BRAF (显示 BRAF ELISA试剂盒)/MEK inhibitor presented more significant redifferentiation effect on papillary thyroid cancer cells harboring BRAFV600E than BRAF (显示 BRAF ELISA试剂盒)/MEK inhibitor alone.

  2. MEK1 is constitutively and mainly phosphorylated at the Thr (显示 TRH ELISA试剂盒)-292, Ser (显示 SIGLEC1 ELISA试剂盒)-298, Thr (显示 TRH ELISA试剂盒)-386, and Thr (显示 TRH ELISA试剂盒)-388 residues in vivo, and combinations of phosphorylations at these four residues produce at least six phosphorylated variants of MEK1. The phosphorylation statuses of Thr (显示 TRH ELISA试剂盒)-292, Ser (显示 SIGLEC1 ELISA试剂盒)-298, Thr (显示 TRH ELISA试剂盒)-386, and Thr (显示 TRH ELISA试剂盒)-388 residues vary widely during activation and deactivation of the MAPK (显示 MAPK1 ELISA试剂盒) pathway.

  3. TNFRSF14 (显示 TNFRSF14 ELISA试剂盒) and MAP2K1 mutations are the most frequent genetic alterations found in pediatric-type follicular lymphoma (PTFL) and occur independently in most cases, suggesting that both mutations might play an important role in PTFL lymphomagenesis.

  4. There was no statistically significant association between BRAF (显示 BRAF ELISA试剂盒) or MAP2K1 mutation and anatomic site, unifocal versus multifocal presentation, or clinical outcome in Langerhans cell histiocytosis.

  5. High MEK1 expression is associated with inflammation.

  6. Lgr4 (显示 LGR4 ELISA试剂盒) is a critical positive factor for skin tumorigenesis by mediating the activation of MEK1/ERK1/2 (显示 MAPK1/3 ELISA试剂盒) and Wnt (显示 WNT2 ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒) pathways.

  7. somatic mutations in MAP2K1 are a common cause of extracranial arteriovenous malformation

  8. MEK1 mutation is associated with central nervous system metastases of non-small cell lung cancer.

  9. The MAP2K1 mutation analysis of three hairy cell leukemia cases, one hairy cell leukemia-variant case, and three splenic marginal zone lymphoma cases revealed negative results.

  10. Data show that mitogen-activated protein kinase (显示 MAPK1 ELISA试剂盒) kinases MEK1/2 inhibitor pimasertib (MEKI) sensitized the cells to apoptosis through its ability to promote a G1 cell cycle arrest.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. fluid shear stress induces autocrine TGF-beta (显示 TGFB1 ELISA试剂盒)/ALK5 (显示 TGFBR1 ELISA试剂盒)-induced target gene expression in renal epithelial cells, which is partially restrained by MEK1/2-mediated signaling.

  2. Lgr4 (显示 LGR4 ELISA试剂盒) is a critical positive factor for skin tumorigenesis by mediating the activation of MEK1/ERK1/2 (显示 MAPK1/3 ELISA试剂盒) and Wnt (显示 WNT2 ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒) pathways.

  3. FGF2 (显示 FGF2 ELISA试剂盒) is an extracellular inducer of COUP-TFII (显示 NR2F2 ELISA试剂盒) expression and may suppress the osteogenic potential of mesenchymal cells by inducing COUP-TFII (显示 NR2F2 ELISA试剂盒) expression prior to the onset of osteogenic differentiation

  4. REDD1 (显示 DDIT4 ELISA试剂盒) is required for normal insulin (显示 INS ELISA试剂盒)-stimulated signaling, and a subtle balance exists between MEK1/2, REDD1 (显示 DDIT4 ELISA试剂盒), and mTOR (显示 FRAP1 ELISA试剂盒)

  5. blood glucose levels are reduced by suppression of MEK1 expression in the liver of db/db (显示 LEPR ELISA试剂盒) mice

  6. MEK1 and MEK2 (显示 MAP2K2 ELISA试剂盒) can substitute for each other but a minimum amount of MEK (显示 MDK ELISA试剂盒) is critical for placenta development and embryo survival

  7. Aberrant phosphorylation of AKT (显示 AKT1 ELISA试剂盒) and MEK (显示 MDK ELISA试剂盒) signalling pathways was identified in cells carrying mutant huntingtin (显示 HTT ELISA试剂盒).

  8. An essential function for MEK1 in macrophages in regulating the ERK1/2 (显示 MAPK1/3 ELISA试剂盒) and STAT4 (显示 STAT4 ELISA试剂盒) pathways in response to TLR4 (显示 TLR4 ELISA试剂盒) activation.

  9. Nuclear enrichment of MEK1 physically sequesters peroxisome proliferator-activated receptor gamma (PPARgamma (显示 PPARG ELISA试剂盒)), inhibiting adipogenesis and disrupting ERK (显示 EPHB2 ELISA试剂盒) signaling.

  10. MEK1 is inhibited by phosphorylation at Thr (显示 TRH ELISA试剂盒)-292/286 by Cdk5 (显示 CDK5 ELISA试剂盒), ERK (显示 EPHB2 ELISA试剂盒), and Cdk1 (显示 CDK1 ELISA试剂盒).

Xenopus laevis Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. in FGFR1 (显示 FGFR1 ELISA试剂盒) signalling JNK1 (显示 MAPK8 ELISA试剂盒) phosphorylation depends on ERK2 (显示 MAPK1 ELISA试剂盒)

  2. The data demonstrate that ERK (显示 MAPK1 ELISA试剂盒) phosphorylation of UBF prevents DNA bending by its first two HMG (显示 SSRP1 ELISA试剂盒) boxes, leading to a cooperative unfolding of the enhancesome

  3. We propose that Erk2 MAP kinase (显示 MAPK1 ELISA试剂盒) phosphorylation of Vg1RBP (显示 IGF2BP3 ELISA试剂盒) regulates the protein:protein-mediated association of Vg1 mRNP with the cytoskeleton and/or ER.

Rabbit Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Extracellular signal-regulated kinase (ERK (显示 MAPK1 ELISA试剂盒)) pathway plays a role in dedifferentiation of rabbit articular chondrocytes.

  2. KSR (显示 KSR1 ELISA试剂盒) interacts with a regulatory Raf (显示 RAF1 ELISA试剂盒) molecule in cis (显示 CISH ELISA试剂盒) to induce a conformational switch of MEK, facilitating MEK's phosphorylation by a separate catalytic Raf (显示 RAF1 ELISA试剂盒) molecule in trans

Pig (Porcine) Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

Arabidopsis thaliana Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) interaction partners

  1. Data indicate that MEKK2 (显示 MAP3K2 ELISA试剂盒) is required for the mekk1 (显示 MAP3K1 ELISA试剂盒), mkk1 mkk2 (显示 MAP2K2 ELISA试剂盒), and mpk4 (显示 MAPK4 ELISA试剂盒) autoimmune phenotypes.

  2. Data suggest that the MEKK1 (显示 MAP3K1 ELISA试剂盒)-MKK1/MKK2 (显示 MAP2K2 ELISA试剂盒)-MPK4 (显示 MAPK4 ELISA试剂盒) kinase cascade negatively regulates MEKK2 (显示 MAP3K2 ELISA试剂盒) and activation of MEKK2 (显示 MAP3K2 ELISA试剂盒) triggers SUMM2-mediated immune responses.

  3. miR (显示 MYLIP ELISA试剂盒)-1826 plays an important role as tumor suppressor via CTNNB1 (显示 CTNNB1 ELISA试剂盒)/MEK1/VEGFC (显示 VEGFC ELISA试剂盒) downregulation in bladder cancer.

  4. ETS1 (显示 ETS1 ELISA试剂盒) is probably mediating high CIP2A (显示 KIAA1524 ELISA试剂盒) expression in human cancers with increased EGFR (显示 EGFR ELISA试剂盒)-MEK1/2-ERK (显示 MAPK1 ELISA试剂盒) pathway activity

  5. An analysis of the interation of MEKK1 (显示 MAP3K1 ELISA试剂盒) and MEK1 in response to wounding stress in A. thaliana seedlings is presented.

  6. This study demonstrated that the MKK1 signalling pathway modulates the expression of genes responding to elicitors and plays an important role in pathogen defence.

  7. These results suggest that the formation of SUMO-1 (显示 SUMO1 ELISA试剂盒) foci is regulated by the MEK-ERK (显示 MAPK1 ELISA试剂盒) pathway and may induce apoptosis.

  8. AtMEK1 is a crucial mediator in plant stress signal transduction.

  9. double loss-of-function mutant (mkk1/2) of MKK1 and MKK2 (显示 MAP2K2 ELISA试剂盒) is shown to have marked phenotypes in development and disease resistance similar to those of the single mekk1 (显示 MAP3K1 ELISA试剂盒) and mpk4 (显示 MAPK4 ELISA试剂盒) mutants

  10. Activation of MPK4 (显示 MAPK4 ELISA试剂盒) by flg22 is impaired in the mkk1 mkk2 (显示 MAP2K2 ELISA试剂盒) double mutants, suggesting that MKK1 and MKK2 (显示 MAP2K2 ELISA试剂盒) function together with MPK4 (显示 MAPK4 ELISA试剂盒) and MEKK1 (显示 MAP3K1 ELISA试剂盒) in a MAP kinase (显示 MAPK1 ELISA试剂盒) cascade to negatively regulate innate immune responses in plants.

MAP2K1 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

Alternative names and synonyms associated with MAP2K1

  • mitogen activated protein kinase kinase 1 (Map2k1) Elisa Kit
  • mitogen-activated protein kinase kinase 1 (MAP2K1) Elisa Kit
  • mitogen-activated protein kinase kinase 1 (Map2k1) Elisa Kit
  • mitogen-activated protein kinase kinase 1 (map2k1) Elisa Kit
  • mitogen-activated protein kinase kinase 1 (MEK1) Elisa Kit
  • ATMEK1 Elisa Kit
  • CFC3 Elisa Kit
  • F20B18.180 Elisa Kit
  • F20B18_180 Elisa Kit
  • MAP kinase/ ERK kinase 1 Elisa Kit
  • MAPKK1 Elisa Kit
  • MEK Elisa Kit
  • mek-2 Elisa Kit
  • MEK1 Elisa Kit
  • MEKK1 Elisa Kit
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE Elisa Kit
  • MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 Elisa Kit
  • MKK1 Elisa Kit
  • NMAPKK Elisa Kit
  • Prkmk1 Elisa Kit
  • si:ch211-242m18.2 Elisa Kit
  • wu:fj56a12 Elisa Kit
  • wu:fj61b01 Elisa Kit
  • zgc:56557 Elisa Kit

Protein level used designations for MAP2K1

ERK activator kinase 1 , MAP kinase kinase 1 , MAP kinase/Erk kinase 1 , MAPK/ERK kinase 1 , MAPKK 1 , dual specificity mitogen-activated protein kinase kinase 1 , mitogen-activated protein kinase kinase 1 , MEK 1 , protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1) , dual specificity mitogen activated protein kinase kinase 1 , mitogen activated protein kinase kinase 1 , protein kinase, mitogen activated, kinase 1, p45 , MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2) , MEK1

GENE ID SPECIES
170851 Rattus norvegicus
5604 Homo sapiens
478347 Canis lupus familiaris
26395 Mus musculus
379991 Xenopus laevis
415549 Gallus gallus
533199 Bos taurus
406728 Danio rerio
100009316 Oryctolagus cuniculus
100233191 Sus scrofa
828713 Arabidopsis thaliana
450188 Pan troglodytes
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