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GCK 抗体

(Glucokinase (Hexokinase 4) (GCK))
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq, Apr 2009].
GCK 抗体  (AA 1-465) GCK 抗体  (AA 1-465) GCK 抗体 (AA 1-465) (ABIN515989)

GCK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

GCK 抗体 GCK 抗体 GCK 抗体 (ABIN969172)

GCK 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4G6 unconjugated

GCK 抗体  (AA 101-200) GCK 抗体  (AA 101-200) GCK 抗体 (AA 101-200) (ABIN734558)

GCK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated

GCK 抗体 by 适用

Find GCK 抗体 for a variety of species such as anti-Human GCK, anti-Mouse GCK, anti-Rat GCK. The species listed below are among those available. Click on a link to go to the corresponding products.

GCK 抗体 by 应用范围

Find GCK 抗体 validated for a specific application such as WB, ELISA, IHC, IF. Some of the available applications are listed below. Click on a link to go to the corresponding products.

GCK 抗体 by 抗体来源

Find GCK 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

GCK 抗体 by 抗原表位

Find GCK 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

GCK 抗体 by 克隆形成能力

Find available monoclonal or polyclonal GCK 抗体. Click on a link to go to the corresponding products.

GCK 抗体 by 克隆

Find GCK 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

GCK 抗体 by 标记

Find GCK 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular GCK 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (6)
Cat. No. ABIN515989
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
  • (3)
Cat. No. ABIN969172
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p), FACS
Validations
  • (1)
  • (2)
Cat. No. ABIN734558
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7429088
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7153890
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7234072
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7237073
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
Cat. No. ABIN515987
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF
Validations
  • (3)
Cat. No. ABIN515988
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
  • (2)
Cat. No. ABIN544490
Quantity 400 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN1078066
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN7188765
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN561021
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN3184762
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN7267396
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our GCK 抗体

Xu, Xiao, Liu, Yang, Zhang, Chen, Chen, Liu, Huang: "Paeonol Ameliorates Glucose and Lipid Metabolism in Experimental Diabetes by Activating Akt." in: Frontiers in pharmacology, Vol. 10, pp. 261, (2019) (PubMed).

Zang, Fan, Chen, Huang, Qin: "Improvement of Lipid and Glucose Metabolism by Capsiate in Palmitic Acid-Treated HepG2 Cells via Activation of the AMPK/SIRT1 Signaling Pathway." in: Journal of agricultural and food chemistry, Vol. 66, Issue 26, pp. 6772-6781, (2018) (PubMed).

Wang, Liu, Chen, Duan, Chen, Xi: "Effects of a Novel Glucokinase Activator, HMS5552, on Glucose Metabolism in a Rat Model of Type 2 Diabetes Mellitus." in: Journal of diabetes research, Vol. 2017, pp. 5812607, (2017) (PubMed).

Tian, Liu, Wang, Dong, Su, Ma, Zhang: "Anti-diabetes effect of chronic intermittent hypobaric hypoxia through improving liver insulin resistance in diabetic rats." in: Life sciences, Vol. 150, pp. 1-7, (2016) (PubMed).

Huang, Chou, Lee, Chen, Chen, Tao, Shih: "MicroRNA-130a can inhibit hepatitis B virus replication via targeting PGC1α and PPARγ." in: RNA (New York, N.Y.), Vol. 21, Issue 3, pp. 385-400, (2015) (PubMed).

Barbetti, Cobo-Vuilleumier, Dionisi-Vici, Toni, Ciampalini, Massa, Rodriguez-Bada, Colombo, Lenzi, Garcia-Gimeno, Bermudez-Silva, Rodriguez de Fonseca, Banin, Aledo, Baixeras, Sanz, Cuesta-Muñoz: "Opposite clinical phenotypes of glucokinase disease: Description of a novel activating mutation and contiguous inactivating mutations in human glucokinase (GCK) gene." in: Molecular endocrinology (Baltimore, Md.), Vol. 23, Issue 12, pp. 1983-9, (2009) (PubMed).

Yoshida, Kato, Yokoi, Oguri, Watanabe, Metoki, Yoshida, Satoh, Aoyagi, Nishigaki, Nozawa, Yamada: "Association of genetic variants with chronic kidney disease in individuals with different lipid profiles." in: International journal of molecular medicine, Vol. 24, Issue 2, pp. 233-46, (2009) (PubMed).

Gloyn, Noordam, Willemsen, Ellard, Lam, Campbell, Midgley, Shiota, Buettger, Magnuson, Matschinsky, Hattersley: "Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations." in: Diabetes, Vol. 52, Issue 9, pp. 2433-40, (2003) (PubMed).

Pruhova, Ek, Lebl, Sumnik, Saudek, Andel, Pedersen, Hansen: "Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha." in: Diabetologia, Vol. 46, Issue 2, pp. 291-5, (2003) (PubMed).

Rizzo, Magnuson, Drain, Piston: "A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin." in: The Journal of biological chemistry, Vol. 277, Issue 37, pp. 34168-75, (2002) (PubMed).

Aliases for GCK 抗体

glucokinase (GCK) 抗体
glucokinase (Gck) 抗体
glucokinase (glcK) 抗体
glucokinase (Bphyt_1025) 抗体
glucokinase (Halhy_6548) 抗体
glucokinase (gk) 抗体
glucokinase (hexokinase 4) L homeolog (gck.L) 抗体
glucokinase (hexokinase 4) (gck) 抗体
BA4487 抗体
FGQTL3 抗体
GCK 抗体
gck-A 抗体
GK 抗体
Gk 抗体
GLK 抗体
glk 抗体
Gls006 抗体
glucokinase 抗体
GLUKA 抗体
HHF3 抗体
hhf3 抗体
HK4 抗体
hk4 抗体
HKIV 抗体
hkiv 抗体
HXKP 抗体
hxkp 抗体
LGLK 抗体
MODY2 抗体
mody2 抗体
RNGK2 抗体
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