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Rat (Rattus) ERK2 ELISA Kit for Sandwich ELISA - ABIN431451
Kiasalari, Baluchnejadmojarad, Roghani: Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson's Disease. in Cellular and molecular neurobiology 2016
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MKP1 (显示 DUSP1 ELISA试剂盒) is a negative regulator of signaling pathways required for some, but not all, early and late pathogen-associated molecular pattern responses.
MKP1 (显示 DUSP1 ELISA试剂盒) and PTP1 act redundantly to suppress salicylic acid and camalexin biosynthesis, and regulate growth homeostasis and PR gene expression in an MPK3 (显示 MAPK3 ELISA试剂盒)- and MPK6 (显示 MAPK6 ELISA试剂盒)-dependent manner.
Regulation of AtMPK1/2 kinase activity in Arabidopsis might be under the control of signals involved in different kinds of stress.
AtMKP2, a novel MKP protein in Arabidopsis, acts upon MPK3 (显示 MAPK3 ELISA试剂盒) and -6, and serves as a positive regulator of the cellular response to oxidant challenge
The present results suggest that demecolcine might contribute to the activation of the Mos (显示 MOCOS ELISA试剂盒)/MAPK pathway and affect spindle structure
MAPK1 upregulated milk protein (显示 CSN2 ELISA试剂盒) synthesis through the Stat5 (显示 STAT5A ELISA试剂盒) and mTOR (显示 FRAP1 ELISA试剂盒) pathways.
Chronic hypoxia induces Egr-1 (显示 EGR1 ELISA试剂盒) via activation of ERK1/2 (显示 MAPK1/3 ELISA试剂盒) and contributes to pulmonary vascular remodeling.
ER Ca(2 (显示 CA2 ELISA试剂盒)+) release enhances eNOS (显示 NOS3 ELISA试剂盒) Ser (显示 SIGLEC1 ELISA试剂盒)-635 phosphorylation and function via ERK1/2 (显示 MAPK1/3 ELISA试剂盒) activation.
Cyclin-dependent kinase (显示 CDK1 ELISA试剂盒) inhibition did not affect the expression (mRNA and protein levels) and localization of maturation promoting factor(MPF (显示 MSLN ELISA试剂盒)) and MAPK, and had nearly no effect on kinase activities during maturation.
Thrombospondin 1 (显示 THBS1 ELISA试剂盒), fibronectin (显示 FN1 ELISA试剂盒), and vitronectin (显示 VTN ELISA试剂盒) are differentially dependent upon RAS, ERK1/2 (显示 MAPK1/3 ELISA试剂盒), and p38 (显示 MAPK14 ELISA试剂盒) for induction of vascular smooth muscle cell chemotaxis.
results suggest that Nav1.7-Ca2+ influx-protein kinase C-alpha pathway activated ERK1/ERK2 and p38, which increased phosphorylation of glycogen synthase kinase-3beta, decreasing tau phosphorylation
These data suggest that Gab1-ERK1/2 (显示 MAPK1/3 ELISA试剂盒) binding and their nuclear translocation play a crucial role in Egr-1 (显示 EGR1 ELISA试剂盒) nuclear accumulation.
Role of CaMKII (显示 CAMK2G ELISA试剂盒) in hydrogen peroxide activation of p38 MAPK (显示 MAPK14 ELISA试剂盒)/heat shock protein 27 (显示 HSP27 ELISA试剂盒) pathway and ERK1/2 (显示 MAPK1/3 ELISA试剂盒)
data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt (显示 AKT1 ELISA试剂盒), mTOR (显示 FRAP1 ELISA试剂盒), p70S6K (显示 RPS6KB1 ELISA试剂盒), and ERK1/2 (显示 MAPK1/3 ELISA试剂盒).
Excess PLAC8 promotes an unconventional ERK2-dependent EMT (显示 ITK ELISA试剂盒) in colon cancer.
ERK1/2 (显示 MAPK1/3 ELISA试剂盒)-Akt1 (显示 AKT1 ELISA试剂盒) crosstalk regulates arteriogenesis in mice and zebrafish.
eena (显示 SH3GL1 ELISA试剂盒) plays an important role in the development of the myeloid cell through activation of the ERK1 (显示 MAPK3 ELISA试剂盒)/ERK2 pathway
ERK1 (显示 MAPK3 ELISA试剂盒) and ERK2 target common and distinct gene sets, confirming diverse roles for these kinases during embryogenesis; for ERK2 genes involved in cell-migration, mesendoderm differentiation and patterning were identified.
These results demonstrate that induction of Hsp70 (显示 HSPA1A ELISA试剂盒) in response to heat stress is dependent on ERK activation in Pac2 (显示 PSMG2 ELISA试剂盒) cells.
Data define distinct roles for ERK1 (显示 MAPK3 ELISA试剂盒) and ERK2 in developmental cell migration processes during zebrafish embryogenesis.
GLUL (显示 GLUL ELISA试剂盒) knockdown markedly inhibited the p38 MAPK (显示 MAPK14 ELISA试剂盒) and ERK1 (显示 MAPK3 ELISA试剂盒)/ERK2 signaling pathways in cultured breast cancer cells and reduces their proliferation.
These results suggested that HOXB7 (显示 HOXB7 ELISA试剂盒) stimulates ERK1/2 (显示 MAPK1/3 ELISA试剂盒) phosphorylation and provided evidence that HOXB7 (显示 HOXB7 ELISA试剂盒), besides its role in transcriptional regulation, also promotes cell motility and invasiveness.
High ERK2 expression is associated with castration-resistant prostate cancer.
combined use of butyrate and highly specific Syk (显示 SYK ELISA试剂盒) inhibitor BAY61-3606 does not enhance differentiation and apoptosis of colonocytes. Instead, BAY completely abolishes butyrate-induced differentiation and apoptosis in a Syk (显示 SYK ELISA试剂盒)- and ERK1/2 (显示 MAPK1/3 ELISA试剂盒)-dependent manner.
new findings indicating that canonical FGFR (显示 FGFR2 ELISA试剂盒)-ERK1/2 (显示 MAPK1/3 ELISA试剂盒) signaling entrapped hBMSCs in a pre-committed state and arrested further maturation of committed precursors.
mutually exclusive transcriptional regulation by AP-1 (cjun (显示 JUN ELISA试剂盒)/cfos) and non-canonical NF-kappaB (显示 NFKB1 ELISA试剂盒) (RelB (显示 RELB ELISA试剂盒)/p52 (显示 FKBP4 ELISA试剂盒)) downstream of MEK (显示 MAP2K1 ELISA试剂盒)-ERK (显示 EPHB2 ELISA试剂盒) and NIK (显示 MAP3K14 ELISA试剂盒)-IKK-alpha (显示 CHUK ELISA试剂盒)-NF-kappaB2 (p100 (显示 CUX1 ELISA试剂盒)) phosphorylation, respectively was responsible for persistent Ccl20 (显示 CCL20 ELISA试剂盒) expression in the colonic cells.
we have demonstrated a pathogenic role for aPL (显示 FASL ELISA试剂盒) containing samples, mediated via aPL (显示 FASL ELISA试剂盒)-b2GPI (显示 APOH ELISA试剂盒) interactions, resulting in activation of the pro-apoptotic p38 MAPK (显示 MAPK14 ELISA试剂盒) pathway.
LPS (显示 IRF6 ELISA试剂盒)-activated ERK1,2 was at least partly involved in the observed effects on periodontal ligament stem cell differentiation capacity, acquisition of myofibroblastic attributes, and changes of their immunomodulatory features.
The findings indicate that ERK (显示 EPHB2 ELISA试剂盒) and JNK (显示 MAPK8 ELISA试剂盒) signaling pathways, as well as NF-kappaB (显示 NFKB1 ELISA试剂盒)-mediated signaling are important contributors to the pathogenesis of Kashin-Beck disease.
observations provide important insights into the regulation of EpCAM (显示 EPCAM ELISA试剂盒) expression during EMT (显示 ITK ELISA试剂盒), demonstrate an unexpected role for EpCAM (显示 EPCAM ELISA试剂盒) in the regulation of ERK (显示 EPHB2 ELISA试剂盒) and define a novel double-negative feedback loop between EpCAM (显示 EPCAM ELISA试剂盒) and ERK (显示 EPHB2 ELISA试剂盒) that contributes to the regulation of EMT (显示 ITK ELISA试剂盒).
Cortical neuron-specific deletion of extracellular signal-regulated kinases Erk1 (显示 MAPK3 ELISA试剂盒) or Erk2 significantly increased the duration of wakefulness.
pERK1/2 is a regulator of CD44 (显示 CD44 ELISA试剂盒) expression, and increased CD44 (显示 CD44 ELISA试剂盒) expression leads to a pro-sclerotic and migratory parietal epithelial cell phenotype in focal segmental glomerulosclerosis.
mmLDL increased the serum concentrations and expression of ICAM-1 (显示 ICAM1 ELISA试剂盒) and VCAM-1 (显示 VCAM1 ELISA试剂盒) by activating the ERK1/2 (显示 MAPK1/3 ELISA试剂盒) pathway, resulting in the expression of ETB (显示 EDNRB ELISA试剂盒) receptors and the enhancement of contractile function in vascular smooth muscle.
These results indicate a crucial role of the Rapgef2 (显示 RAPGEF2 ELISA试剂盒)-Rap1A (显示 RAP1A ELISA试剂盒)-ERK (显示 EPHB2 ELISA试剂盒)-c-jun (显示 JUN ELISA试剂盒) pathway in regulation of the AJ formation in RGCs.
MFA has a protective effect on alcohol-induced liver injury, which may be related to its antioxidant,anti-inflammatory,lipid-eliminating properties and its ability to regulate the NOX4 (显示 NOX4 ELISA试剂盒)/ROS (显示 ROS1 ELISA试剂盒)-MAPK signalling pathway.
MAPK3 (显示 MAPK3 ELISA试剂盒)/1 participates in primordial follicle activation through mTORC1-KITL (显示 KITLG ELISA试剂盒) signaling.
The purpose of this study was to investigate mechanisms that govern the regulation of Npnt (显示 NPNT ELISA试剂盒) gene expression by IL-1beta (显示 IL1B ELISA试剂盒) in osteoblasts.
The results of this study suggested that Erk2 activation in astrocytes plays a crucial role in aggravating demyelinating inflammation by inducing inflammatory mediators and gliosis.
At low oxLDL levels LOX-1 (显示 OLR1 ELISA试剂盒) activates the protective Oct-1 (显示 POU2F1 ELISA试剂盒)/SIRT1 (显示 SIRT1 ELISA试剂盒) pathway, while at higher levels of the lipoprotein switches to the thrombogenic ERK1/2 (显示 MAPK1/3 ELISA试剂盒) pathway.
Studies indicate that progesterone receptor (显示 PGR ELISA试剂盒) transgenic (Pgrcre/+) mitogen inducible gene 6 (Mig (显示 CXCL9 ELISA试剂盒)-6over) phosphatase and tensin homolog protein (Ptenf/f) knockout mice exhibited an increase of phospho-ERK1/2 (显示 MAPK1/3 ELISA试剂盒) and its target genes.
Early activation of MAPK p44/42 is involved in deoxynivalenol -induced disruption of intestinal barrier function and tight junction network signaling.
Agonist stimulation of vascular smooth muscle increases PKC (显示 FYN ELISA试剂盒) activity, which, in turn, increases MKP-1 (显示 DUSP1 ELISA试剂盒) activity and maintains MAPK1 activity at submaximal values.
sub-vasomotor concentration of ET-1 (显示 EDN1 ELISA试剂盒) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (显示 MAPK14 ELISA试剂盒) kinase-mediated production of superoxide from NADPH oxidase (显示 NOX1 ELISA试剂盒) following ETA receptor activation
Treatment with ERK inhibitors or ERK1/2 (显示 MAPK1/3 ELISA试剂盒) knockdown significantly suppressed porcine epidemic diarrhea virus progeny production.
This study reveals a new function of the gE glycoprotein of pseudorabies virus and suggests that pseudorabies virus, through activation of ERK1/2 (显示 MAPK1/3 ELISA试剂盒) signaling, has a substantial impact on T cell behavior.
CSF2 (显示 CSF2 ELISA试剂盒) stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 (显示 MAPK1/3 ELISA试剂盒) MAPK-dependent MTOR (显示 FRAP1 ELISA试剂盒) signal transduction cascades.
PGRN (显示 GRN ELISA试剂盒) inhibits adipogenesis in porcine preadipocytes partially through ERK activation mediated PPARgamma (显示 PPARG ELISA试剂盒) phosphorylation.
Data show that proinflammatory cytokines induction was ERK1/2 (显示 MAPK1/3 ELISA试剂盒) and JNK1 (显示 MAPK8 ELISA试剂盒)/2 dependent.
The authors show that porcine circovirus type 2 (PCV2) activates ERK1/2 (显示 MAPK1/3 ELISA试剂盒) in PCV2-infected PK15 cells dependent on viral replication.
20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.
Here the authors show that CPEB4 activity is regulated by ERK2- and Cdk1-mediated hyperphosphorylation. These phosphorylation events additively activate CPEB4 in M-phase by maintaining it in its monomeric state.
The reciprocal feedback observed between MPF (显示 MSLN ELISA试剂盒) and ERK2 in meiosis is not observed during mitotic M-phase in cell-free Xenopus embryo extracts.
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.
mitogen-activated protein kinase 1
, MAP kinase 1
, MAP kinase 2
, MAPK 1
, MAPK 2
, extracellular signal-regulated kinase 2
, mitogen-activated protein kinase 2
, MAP kinase isoform p42
, protein tyrosine kinase ERK2
, mitogen activated protein kinase 1
, extracellular-signal-regulated kinase 2
, extracellular signal-regulated kinase-2
, MAP kinase
, mitogen-activated protein kinase 1b
, myelin basic protein kinase-like protein
, mitogen-activated protein kinase 1a