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Cortactin 蛋白

(Cortactin (CTTN))
This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene. [provided by RefSeq, May 2010].
Cortactin Protein (CTTN) (AA 341-450) (GST tag) Cortactin Protein (CTTN) (AA 341-450) (GST tag) Cortactin Protein (CTTN) (AA 341-450) (GST tag) (ABIN1350743)

CTTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Cortactin Protein (CTTN) (AA 1-513) (GST tag) Cortactin Protein (CTTN) (AA 1-513) (GST tag) Cortactin Protein (CTTN) (AA 1-513) (GST tag) (ABIN1350741)

CTTN 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

Cortactin Protein (CTTN) (AA 1-546) (His tag) Cortactin Protein (CTTN) (AA 1-546) (His tag) Cortactin Protein (CTTN) (AA 1-546) (His tag) (ABIN3135267)

Crystallography grade CTTN 宿主: 小鼠 宿主: 大肠杆菌(E. Coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

Cortactin 蛋白 by Grade

Find Cortactin 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Cortactin 蛋白 by Origin

Find Cortactin 蛋白 for a variety of species such as anti-Human Cortactin, anti-Mouse Cortactin, anti-Rat Cortactin. The species listed below are among those available. Click on a link to go to the corresponding products.

Cortactin 蛋白 by Source

Here you will find Cortactin 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

Cortactin 蛋白 by 蛋白类型

Here you can find Cortactin 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

Cortactin 蛋白 by 应用范围

Find Cortactin 蛋白 validated for a specific application such as WB, ELISA, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular Cortactin 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350743
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350741
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3135267
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN3095566
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
  • (1)
Cat. No. ABIN2712518
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417507
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417462
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (1)
Cat. No. ABIN2712519
Quantity 20 μg
Datasheet Datasheet

Latest Publications for our Cortactin 蛋白

Cortés-Vicente, Gallardo, Martínez, Díaz-Manera, Querol, Rojas-García, Illa: "Clinical Characteristics of Patients With Double-Seronegative Myasthenia Gravis and Antibodies to Cortactin." in: JAMA neurology, Vol. 73, Issue 9, pp. 1099-104, (2016) (PubMed).

Labrador-Horrillo, Martínez, Selva-OCallaghan, Trallero-Araguás, Grau-Junyent, Vilardell-Tarrés, Juarez: "Identification of a novel myositis-associated antibody directed against cortactin." in: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1008-12, (2014) (PubMed).

Gallardo, Martínez-Hernández, Titulaer, Huijbers, Martínez, Ramos, Querol, Díaz-Manera, Rojas-García, Hayworth, Verschuuren, Balice-Gordon, Dalmau, Illa: "Cortactin autoantibodies in myasthenia gravis." in: Autoimmunity reviews, Vol. 13, Issue 10, pp. 1003-7, (2014) (PubMed).

Wang, Henry, Distefano, Wang, Räikkönen, Mönkkönen, Tanaka, Morita: "Butyrophilin 3A1 plays an essential role in prenyl pyrophosphate stimulation of human V?2V?2 T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 3, pp. 1029-42, (2013) (PubMed).

Llanos, Royer, Lu, Bergamaschi, Lee, Lu: "Inhibitory member of the apoptosis-stimulating proteins of the p53 family (iASPP) interacts with protein phosphatase 1 via a noncanonical binding motif." in: The Journal of biological chemistry, Vol. 286, Issue 50, pp. 43039-44, (2011) (PubMed).

Aliases for Cortactin 蛋白

cortactin (CTTN) 蛋白
cortactin (Cttn) 蛋白
CG3637 gene product from transcript CG3637-RD (Cortactin) 蛋白
cortactin S homeolog (cttn.S) 蛋白
cortactin L homeolog (cttn.L) 蛋白
cortactin (cttn) 蛋白
src substrate cortactin (CpipJ_CPIJ006351) 蛋白
Src substrate cortactin (Bm1_57220) 蛋白
cortactin (LOC100533277) 蛋白
1110020L01Rik 蛋白
CG3637 蛋白
cortactin 蛋白
cttn 蛋白
Cttn 蛋白
CTTN 蛋白
CTTN1 蛋白
Cttnb 蛋白
Dmel\CG3637 蛋白
EMS1 蛋白
Ems1 蛋白
ems1 蛋白
P85.25 蛋白
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