anti-BRAF (BRAF) 抗体产品概述

Full name:
anti-V-Raf Murine Sarcoma Viral Oncogene Homolog B1 抗体 (BRAF)
在www.antibodies-online.cn可供405 V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) 抗体的24不同的供货商。 再加上,我们可以发BRAF 蛋白 (34)BRAF 试剂盒 (7)和数多这个蛋白质的别的产品。 总共468 BRAF产品已列进来了。
别名:
9930012E13Rik, AA120551, AA387315, AA473386, B-raf, B-RAF1, Braf, Braf-2, BRAF1, Braf2, C-RMIL, C87398, C230098H17, D6Ertd631e, HYPT11, NS7, RAFB1, RMIL, sierrabraf, Sm-E, SME

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引用最多的anti-BRAF 抗体

  1. Human Polyclonal BRAF Primary Antibody for EIA - ABIN358444 : Loewe, Kittler, Fischer, Faé, Wolff, Petzelbauer: BRAF kinase gene V599E mutation in growing melanocytic lesions. in The Journal of investigative dermatology 2004 (PubMed)
    Show all 5 references for 358444

  2. Human Polyclonal BRAF Primary Antibody for EIA - ABIN358356 : Yamaguchi, Wallace, Magenheimer, Hempson, Grantham, Calvet: Calcium restriction allows cAMP activation of the B-Raf/ERK pathway, switching cells to a cAMP-dependent growth-stimulated phenotype. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 references for 358356

  3. Human Polyclonal BRAF Primary Antibody for EIA - ABIN358271 : Tsavachidou, Coleman, Athanasiadis, Li, Licht, Olson, Weber: SPRY2 is an inhibitor of the ras/extracellular signal-regulated kinase pathway in melanocytes and melanoma cells with wild-type BRAF but not with the V599E mutant. in Cancer research 2004 (PubMed)
    Show all 5 references for 358271

  4. Human Polyclonal BRAF Primary Antibody for EIA - ABIN358344 : Frattini, Ferrario, Bressan, Balestra, De Cecco, Mondellini, Bongarzone, Collini, Gariboldi, Pilotti, Pierotti, Greco: Alternative mutations of BRAF, RET and NTRK1 are associated with similar but distinct gene expression patterns in papillary thyroid cancer. in Oncogene 2004 (PubMed)
    Show all 5 references for 358344

  5. Human Polyclonal BRAF Primary Antibody for EIA, IHC (p) - ABIN360131 : Hingorani, Jacobetz, Robertson, Herlyn, Tuveson: Suppression of BRAF(V599E) in human melanoma abrogates transformation. in Cancer research 2003 (PubMed)
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  6. Human Polyclonal BRAF Primary Antibody for EIA, IHC (p) - ABIN360136 : Lee, Yoo, Soung, Kim, Park, Kim, Lee, Park, Cho, Kim, Ko, Kim, Nam, Lee, Lee: BRAF mutations in non-Hodgkin's lymphoma. in British journal of cancer 2003 (PubMed)
    Show all 3 references for 360136

  7. Human Polyclonal BRAF Primary Antibody for EIA, IHC (p) - ABIN360132 : Davies, Bignell, Cox, Stephens, Edkins, Clegg, Teague, Woffendin, Garnett, Bottomley, Davis, Dicks, Ewing, Floyd, Gray, Hall, Hawes, Hughes, Kosmidou, Menzies, Mould, Parker, Stevens, Watt, Hooper et al.: Mutations of the BRAF gene in human cancer. ... in Nature 2002 (PubMed)
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  8. Human Polyclonal BRAF Primary Antibody for DB - ABIN389897 : Duan, Cobb: Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 references for 389897

  9. Human Polyclonal BRAF Primary Antibody for IHC (p), WB - ABIN392248 : Naoki, Chen, Richards, Sugarbaker, Meyerson: Missense mutations of the BRAF gene in human lung adenocarcinoma. in Cancer research 2002 (PubMed)
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更多抗BRAF的相互作用对抗体

Xenopus laevis V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. BRAF alternative splicing is differentially regulated in vertebrates. Exon 9b is present in all vertebrates, including Xenopus, but exon 8b is present only in eutherians.

Zebrafish V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. Gene expression studies nominated TWIST2 (显示 TWIST2 抗体) as a key effector downstream of BRAF.

  2. BRAF alternative splicing is differentially regulated in vertebrates. Exon 9b is present in all vertebrates, including Danio rerio, but exon 8b is present only in eutherians.

  3. BRAF activation is sufficient for f-nevus formation, and is among the primary events in melanoma development.

Chimpanzee V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. BRAF alternative splicing is differentially regulated in rodent and primates. Exon 9b is present in vertebrates but exon 8b is present only in eutherians.

Mouse (Murine) V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. This study detected the BrafV637E mutation by whole-exome analysis in 4/4 hepatic tumors induced by neonatal treatment with diethylnitrosamine (DEN) in male B6C3F1 mice.

  2. a critical threshold for inhibition of MAPK (显示 MAPK1 抗体) signaling is required to optimally restore expression of thyroid differentiation genes in thyroid cells and in mice with BrafV600E-induced thyroid cancer.

  3. A- and B-Raf ablation in chondrocytes does not alter skeletal development, whereas ablation of C-Raf decreases hypertrophic chondrocyte apoptosis and impairs vascularization of the growth plate. However, ablation of C-Raf does not impair phosphate-induced ERK1/2 phosphorylation in vitro, but leads to rickets by decreasing VEGF protein stability.

  4. these contrasting signatures precisely match those proposed to confer bias toward Hras (显示 HRAS 抗体)(CAA61CTA) versus Braf(GTG636GAG) mutations in the original tumor sets. Our findings highlight a novel mechanism whereby exposure history acts through strand-biased mutagenesis to specify activation of preferred oncogenes

  5. these results suggest that the activation of 5-HT1D receptors selectively enhanced IA via the Gbetagamma of the Go-protein, PKA, and the sequential B-Raf (显示 SNRPE 抗体)-dependent p38 MAPK (显示 MAPK14 抗体) signaling cascade.

  6. BRAF V600E inhibition stimulates AMP-activated protein kinase (显示 PRKAA2 抗体)-mediated autophagy in colorectal cancer cells.

  7. these data confirm the existence of a negative feedback pathway by which BRAF protein stability is regulated by ERK (显示 EPHB2 抗体).

  8. coexpression of BRAF(V600E) and KRAS(G12D) in early tumorigenesis leads to negative selection due to oncogene (显示 RAB1A 抗体)-induced senescence

  9. findings suggest that targeting ErbB-3 (显示 ERBB3 抗体) receptors could represent an effective therapeutic approach in BRAF-V600E mutant colon cancer

  10. Atg7 (显示 ATG7 抗体) Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma

Human V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. Increased plasma membrane abundance of PMCA4b (显示 ATP2B4 抗体) in vemurafenib-treated BRAF mutant cells is associated with enhanced Ca2 (显示 CA2 抗体)+ clearance.

  2. Data indicate the role of immunohistochemical BRAF V600E expression in patients at the time of progression.

  3. BRAF, FGFR1 (显示 FGFR1 抗体), and MYB (显示 MYB 抗体) mutations occur at high frequency and align with morphology of low-grade neuroepithelial tumors

  4. In this report, we describe a 35-year-old female who presented with multifocal ganglioglioma, involving both the conus medullaris and filum terminale. The dominant lesion in the filum terminale was resected, which revealed World Health Organization I grade, p53 (显示 TP53 抗体) mutant, and BRAF wildtype status

  5. Studies indicate the clinical importance of BRAF-V600 mutations and BRAF inhibition in the progression to melanoma brain metastasis.

  6. IRP2 (显示 IREB2 抗体) expression was associated with mutations in BRAF.

  7. BRAF mutations were present in 44.6% of primary papillary thyroid carcinomas, 41.7% of lymph node metastasis, and 23.8% of distant metastasis.

  8. Mutation in BRAF gene is associated with Pancreatic Ductal Adenocarcinoma.

  9. Patients with BRAF V600E PLGG exhibited poor outcomes after chemotherapy and radiation therapies that resulted in a 10-year progression-free survival of 27% (95% CI, 12.1% to 41.9%) and 60.2% (95% CI, 53.3% to 67.1%) for BRAF V600E and wild-type PLGG, respectively ( P < .001).

  10. RNF43 (显示 RNF43 抗体) germline and somatic mutation in Serrated Neoplasia pathway associated with BRAF mutation.

Horse (Equine) V-Raf Murine Sarcoma Viral Oncogene Homolog B1 (BRAF) interaction partners

  1. BRAF alternative splicing is differentially regulated in rodent and primates. Exon 9b is present in vertebrates but exon 8b is present only in eutherians.

BRAF 抗原简介

Antigen Summary

This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.

Alternative names and synonyms associated with BRAF

  • v-raf murine sarcoma viral oncogene homolog B (braf) 抗体
  • v-raf murine sarcoma viral oncogene homolog B1 (braf) 抗体
  • v-raf murine sarcoma viral oncogene homolog B1 (BRAF) 抗体
  • v-raf murine sarcoma viral oncogene homolog B1 (LOC100219601) 抗体
  • Braf transforming gene (Braf) 抗体
  • Braf transforming gene, related sequence 1 (Braf-rs1) 抗体
  • small nuclear ribonucleoprotein polypeptide E (SNRPE) 抗体
  • v-raf murine sarcoma viral oncogene homolog B (BRAF) 抗体
  • v-raf murine sarcoma viral oncogene homolog B (Braf) 抗体
  • 9930012E13Rik 抗体
  • AA120551 抗体
  • AA387315 抗体
  • AA473386 抗体
  • B-raf 抗体
  • B-RAF1 抗体
  • Braf 抗体
  • Braf-2 抗体
  • BRAF1 抗体
  • Braf2 抗体
  • C-RMIL 抗体
  • C87398 抗体
  • C230098H17 抗体
  • D6Ertd631e 抗体
  • HYPT11 抗体
  • NS7 抗体
  • RAFB1 抗体
  • RMIL 抗体
  • sierrabraf 抗体
  • Sm-E 抗体
  • SME 抗体

Protein level used designations for BRAF

B-Raf , serine/threonine protein kinase BRAF , v-raf murine sarcoma viral oncogene homolog B1 , serine/threonine-protein kinase B-raf , serine/threonine-protein kinase B-raf-like , B-Raf proto-oncogene serine/threonine-protein kinase (p94) , proto-oncogene B-Raf , sm protein E , small nuclear ribonucleoprotein E , snRNP-E , 94 kDa B-raf protein , murine sarcoma viral (v-raf) oncogene homolog B1 , B-raf protein , B-Raf proto-oncogene serine/threonine-protein kinase , proto-oncogene c-Rmil , rmil serine/threonine-protein kinase , serine/threonine kinase , serine/threonine-protein kinase Rmil

GENE ID SPECIES
398973 Xenopus laevis
403065 Danio rerio
463781 Pan troglodytes
100219601 Taeniopygia guttata
100442288 Pongo abelii
109880 Mus musculus
110709 Mus musculus
6635 Homo sapiens
673 Homo sapiens
114486 Rattus norvegicus
536051 Bos taurus
475526 Canis lupus familiaris
396239 Gallus gallus
100065760 Equus caballus
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