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B-Cell Linker 抗体

(B-Cell Linker (BLNK))
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012].
B-Cell Linker 抗体 B-Cell Linker 抗体 B-Cell Linker 抗体 (ABIN968984)

BLNK 适用: 人, 小鼠 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 5G9 unconjugated

B-Cell Linker 抗体  (AA 65-314) B-Cell Linker 抗体  (AA 65-314) B-Cell Linker 抗体 (AA 65-314) (ABIN7441781)

BLNK 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

B-Cell Linker 抗体  (AA 301-400) B-Cell Linker 抗体  (AA 301-400) B-Cell Linker 抗体 (AA 301-400) (ABIN526104)

BLNK 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 1D7 unconjugated

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Find B-Cell Linker 抗体 for a variety of species such as anti-Human B-Cell Linker, anti-Mouse B-Cell Linker, anti-Rat B-Cell Linker. The species listed below are among those available. Click on a link to go to the corresponding products.

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Popular B-Cell Linker 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (2)
  • (6)
Cat. No. ABIN968984
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (6)
Cat. No. ABIN7441781
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, PLA
Validations
  • (4)
Cat. No. ABIN526104
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IF
Validations
  • (4)
Cat. No. ABIN184602
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro)
Validations
  • (1)
  • (2)
Cat. No. ABIN683458
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN7145158
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6260272
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
Cat. No. ABIN6256814
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7246031
Quantity 200 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application IHC, IF
Validations
  • (2)
Cat. No. ABIN7073174
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7139078
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7243052
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (2)
Cat. No. ABIN526103
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IF, ICC
Validations
  • (2)
Cat. No. ABIN2855863
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (3)
  • (1)
Cat. No. ABIN541866
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our B-Cell Linker 抗体

Luger, Yang, Raviv, Weinberg, Banerjee, Lee, Trepel, Yang, Wakefield: "Expression of the B-cell receptor component CD79a on immature myeloid cells contributes to their tumor promoting effects." in: PLoS ONE, Vol. 8, Issue 10, pp. e76115, (2013) (PubMed).

Pighi, Gu, Dalai, Barbi, Parolini, Bertolaso, Pedron, Parisi, Ren, Cecconi, Chilosi, Menestrina, Zamò: "Phospho-proteomic analysis of mantle cell lymphoma cells suggests a pro-survival role of B-cell receptor signaling." in: Cellular oncology (Dordrecht), Vol. 34, Issue 2, pp. 141-53, (2011) (PubMed).

Imamura, Oda, Katahira, Bundo, Pike, Ratcliffe, Kitamura: "BLNK binds active H-Ras to promote B cell receptor-mediated capping and ERK activation." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9804-13, (2009) (PubMed).

Espeli, Mancini, Breton, Poirier, Schiff: "Impaired B-cell development at the pre-BII-cell stage in galectin-1-deficient mice due to inefficient pre-BII/stromal cell interactions." in: Blood, Vol. 113, Issue 23, pp. 5878-86, (2009) (PubMed).

Kamino, Futamura, Nakamura, Kitamura, Kabu, Arakawa: "B-cell linker protein prevents aneuploidy by inhibiting cytokinesis." in: Cancer science, Vol. 99, Issue 12, pp. 2444-54, (2008) (PubMed).

Koretzky, Abtahian, Silverman: "SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond." in: Nature reviews. Immunology, Vol. 6, Issue 1, pp. 67-78, (2006) (PubMed).

Wu, Koretzky: "The SLP-76 family of adapter proteins." in: Seminars in immunology, Vol. 16, Issue 6, pp. 379-93, (2004) (PubMed).

Taguchi, Kiyokawa, Takenouch, Matsui, Tang, Nakajima, Suzuki, Shiozawa, Saito, Katagiri, Takahashi, Karasuyama, Matsuo, Okita, Fujimoto: "Deficiency of BLNK hampers PLC-gamma2 phosphorylation and Ca2+ influx induced by the pre-B-cell receptor in human pre-B cells." in: Immunology, Vol. 112, Issue 4, pp. 575-82, (2004) (PubMed).

Janssen, Zhang: "Adaptor proteins in lymphocyte activation." in: Current opinion in immunology, Vol. 15, Issue 3, pp. 269-76, (2003) (PubMed).

Kersseboom, Middendorp, Dingjan, Dahlenborg, Reth, Jumaa, Hendriks: "Bruton's tyrosine kinase cooperates with the B cell linker protein SLP-65 as a tumor suppressor in Pre-B cells." in: The Journal of experimental medicine, Vol. 198, Issue 1, pp. 91-8, (2003) (PubMed).

Aliases for B-Cell Linker 抗体

B-cell linker (BLNK) 抗体
B-cell linker (blnk) 抗体
B cell linker (Blnk) 抗体
B-cell linker (Blnk) 抗体
AGM4 抗体
BASH 抗体
Bca 抗体
bca 抗体
BLNK 抗体
blnk 抗体
BLNK-S 抗体
Ly-57 抗体
Ly57 抗体
LY57 抗体
Lyw-57 抗体
MGC147045 抗体
SLP-65 抗体
SLP65 抗体
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