anti-Filamin A (FLNA) 抗体产品概述

Full name:
anti-Filamin A, alpha 抗体 (FLNA)
在www.antibodies-online.cn可供151 Filamin A, alpha (FLNA) 抗体的17不同的供货商。 再加上,我们可以发Filamin A 试剂盒 (32)Filamin A 蛋白 (3)和数多这个蛋白质的别的产品。 总共192 Filamin A产品已列进来了。
别名:
ABP-280, ABPX, cb967, CG3937, Cher, CSBS, CVD1, Dilp2, Dmel\\CG3937, F730004A14Rik, fb98b06, Fil, filamin-1, FLN, FLN-A, Fln1, flna, FMD, joy, MGC147094, MNS, NHBP, OPD, OPD1, OPD2, RGD1560614, sko, wu:fb98b06, wu:fd09g03, wu:fd18g06, wu:fd49a06, XLVD, XMVD

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引用最多的anti-Filamin A 抗体

  1. Human Monoclonal Filamin A Primary Antibody for IHC (p), PLA - ABIN560922 : Valente, Logan, Mougou-Zerelli, Lee, Silhavy, Brancati, Iannicelli, Travaglini, Romani, Illi, Adams, Szymanska, Mazzotta, Lee, Tolentino, Swistun, Salpietro, Fede, Gabriel, Russ, Cibulskis, Sougnez et al.: Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes. ... in Nature genetics 2010 (PubMed)
    Show all 7 references for 560922

  2. Human Monoclonal Filamin A Primary Antibody for WB - ABIN1882243 : Gorlin, Yamin, Egan, Stewart, Stossel, Kwiatkowski, Hartwig: Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. in The Journal of cell biology 1990 (PubMed)
    Show all 6 references for 1882243

  3. Human Polyclonal Filamin A Primary Antibody for ICC, IF - ABIN188803 : Thoms, Loveridge, Simpson, Clipson, Reinhardt, Dunlop, Stark: Nucleolar targeting of RelA(p65) is regulated by COMMD1-dependent ubiquitination. in Cancer research 2010 (PubMed)
    Show all 2 references for 188803

  4. Human Polyclonal Filamin A Primary Antibody for FACS, IF - ABIN392193 : Maceyka, Alvarez, Milstien, Spiegel: Filamin A links sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 at lamellipodia to orchestrate cell migration. in Molecular and cellular biology 2008 (PubMed)

更多抗Filamin A的相互作用对抗体

Zebrafish Filamin A, alpha (FLNA) interaction partners

  1. Knockdown of filamin A or vimentin (显示 VIM 抗体) in normal cells profoundly suppresses apical extrusion of the neighbouring transformed cells.

Fruit Fly (Drosophila melanogaster) Filamin A, alpha (FLNA) interaction partners

  1. Here we show using Drosophila indirect flight mus (显示 KPTN 抗体)cle that t (显示 FLNC 抗体)he filamin ortholog Cheerio in conjunction with the giant elastic protein titin plays a crucial role in keeping thin filaments stably anchored at the Z-disc. We identify the filamin domains required for interaction with the (显示 TTN 抗体) titin ortholog Sallimus, and we demonstrate a genetic interaction of filamin with titin and actin.

  2. study identifies Cher as a new target of JNK (显示 MAPK8 抗体) signaling that links cytoskeleton dynamics to tumor progression.

  3. Data indicate that during embryonic development, the expression of Filamin and Ten-m partially overlap in ectodermal cells.

  4. Filamin is required for ovarian follicle cell motility during oogenesis.

Human Filamin A, alpha (FLNA) interaction partners

  1. CCR2B (显示 CCR2 抗体) and beta2AR (显示 ADRB2 抗体) signals to FLNa to stimulate its endocytosis and recycling to the plasma membrane.

  2. In humans, mutations in the actin-binding protein (显示 KPTN 抗体) Filamin-C (显示 FLNC 抗体) result in myopathies, but the underlying molecular function is not well understood. Here we show using Drosophila indirect flight muscle that the filamin ortholog Cheerio in conjunction with the giant elastic protein titin (显示 TTN 抗体) plays a crucial role in keeping thin filaments stably anchored at the Z-disc

  3. Case Report: Reduced binding of mutant FLNa to beta3 and the facilitated recruitment of talin by beta3 on platelet stimulation, explaining the increased alphaIIbbeta3 activation and the ensuing gain-of-platelet functions.

  4. results reveal an unusual structural and thermodynamic basis for the P2204L-induced dysfunction of filamin and frontometaphyseal dysplasia disease.

  5. Mechanistic analysis revealed that FLNA suppresses pol III gene transcription by confining the recruitment of the RNA pol III transcription machinery at the promoters of the genes that are sensitive to the alteration of FLNA expression.

  6. FlnA more strongly binds RhoA (显示 RHOA 抗体), although both filamins overlap with RhoA (显示 RHOA 抗体) expression in the cell cytoplasm. FlnA promotes RhoA (显示 RHOA 抗体) activation whereas FlnB (显示 FLNB 抗体) indirectly inhibits this pathway. Moreover, FlnA loss leads to diminished expression of b1-integrin, whereas FlnB (显示 FLNB 抗体) loss promotes integrin expression

  7. FLNA can function as a modulator of chemosensitivity to docetaxel in triple-negative breast cancer (TNBC) cells through regulation of the MAPK/ERK (显示 MAPK1 抗体) pathway both in vitro and in vivo. FLNA may serve as a novel therapeutic target for improvement of chemotherapy efficacy in TNBC.

  8. Results indicate that mTORC2 (显示 CRTC2 抗体) regulates filamin A-dependent focal adhesions and cell migration.

  9. the actin-binding protein (显示 KPTN 抗体) filamin-A has a critical role in incorporation of Tissue factor (显示 F3 抗体) into extracellular vesicles and secretion of extracellular vesicles from ovarian cancer cells exposed to hypoxia

  10. The syndrome affecting the family shares phenotypic overlap with other syndromes caused by FLNA mutations, but appears to be a distinct phenotype, likely representing a unique genetic syndrome.

Pig (Porcine) Filamin A, alpha (FLNA) interaction partners

  1. filamin reduces ENaC (显示 SCNN1A 抗体) channel function through direct interaction on the cell surface

Mouse (Murine) Filamin A, alpha (FLNA) interaction partners

  1. FlnA binding to PACSIN2 (显示 PACSIN2 抗体) F-BAR domain regulates membrane tubulation in megakaryocytes and platelets.

  2. FlnA is a critical upstream element of the signaling cascade underlying the myogenic tone.

  3. Bones lacking filamin A are protected from estrogen-mediated post-menopausal osteoporosis

  4. findings suggest a model in which filamin A local translation following axon injury controls localized HDAC5 (显示 HDAC5 抗体) activity to promote axon regeneration.

  5. Deletion of filamin A in endothelial cells aggravated myocardial infarction-induced left ventricle dysfunction and cardiac failure as a result of defective endothelial response

  6. A new signaling set, phosphatidic acid-S6K1-FLNA-actin, sheds light into the morphogenic pathway of cytoskeletal structures that are crucial for adhesion and cell locomotion during inflammation and metastasis.

  7. Filamin-A is associated with neutrophil uropod retraction.

  8. Analysis of editing in the filamin A encoding mRNA shows very high editing levels outside the nervous system; further shows FLNA editing is mainly achieved by ADAR2 (显示 ADARB1 抗体) but that in some cases ADAR1 (显示 ADAR 抗体) can efficiently compensate for ADAR2 (显示 ADARB1 抗体).

  9. Filamin a, b-interacting proteins, Cfm1 and Cfm2, are essential for the formation of cartilaginous skeleton.

  10. a major function of FLNa in modulating ion channel abundance and membrane trafficking in neurons, thereby shaping their biophysical properties and function.

Filamin A (FLNA) 抗原简介

Antigen Summary

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Filamin A (FLNA)

  • filamin A, alpha (actin binding protein 280) (flna) 抗体
  • filamin A, alpha (FLNA) 抗体
  • filamin B, like (flnbl) 抗体
  • filamin A, alpha (flna) 抗体
  • cheerio (cher) 抗体
  • filamin A, alpha (Flna) 抗体
  • filamin, alpha (Flna) 抗体
  • ABP-280 抗体
  • ABPX 抗体
  • cb967 抗体
  • CG3937 抗体
  • Cher 抗体
  • CSBS 抗体
  • CVD1 抗体
  • Dilp2 抗体
  • Dmel\\CG3937 抗体
  • F730004A14Rik 抗体
  • fb98b06 抗体
  • Fil 抗体
  • filamin-1 抗体
  • FLN 抗体
  • FLN-A 抗体
  • Fln1 抗体
  • flna 抗体
  • FMD 抗体
  • joy 抗体
  • MGC147094 抗体
  • MNS 抗体
  • NHBP 抗体
  • OPD 抗体
  • OPD1 抗体
  • OPD2 抗体
  • RGD1560614 抗体
  • sko 抗体
  • wu:fb98b06 抗体
  • wu:fd09g03 抗体
  • wu:fd18g06 抗体
  • wu:fd49a06 抗体
  • XLVD 抗体
  • XMVD 抗体

Protein level used designations for anti-Filamin A, alpha (FLNA) 抗体

fd09g03 , filamin A, alpha (actin binding protein 280) , filamin B, like , filamin A, alpha , filamin-A , CG3937-PA , CG3937-PB , CG3937-PF , CG3937-PG , CG3937-PH , CG3937-PI , CG3937-PK , CG3937-PL , CG3937-PM , CG3937-PN , Filamin-1 , Filamin-A , cher-PA , cher-PB , cher-PF , cher-PG , cher-PH , cher-PI , cher-PK , cher-PL , cher-PM , cher-PN , filamin , filamin B , filamin isoform B , filamin-240 , shi kong , actin binding protein 280 , alpha-filamin , endothelial actin-binding protein , filamin-1 , non-muscle filamin , Endothelial actin-binding protein 280) , filamin, alpha , 450 kDa protein , FLN-A , GENA 379 , actin-binding protein 280 , dilated pupils 2 , filamin A

GENE ID SPECIES
562529 Danio rerio
699524 Macaca mulatta
569979 Danio rerio
587317 Strongylocentrotus purpuratus
779840 Xenopus (Silurana) tropicalis
100137263 Papio anubis
42066 Drosophila melanogaster
100380643 Salmo salar
2316 Homo sapiens
293860 Rattus norvegicus
481084 Canis lupus familiaris
733585 Sus scrofa
281165 Bos taurus
100328754 Oryctolagus cuniculus
100725162 Cavia porcellus
395261 Gallus gallus
101120390 Ovis aries
192176 Mus musculus
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