CDK5RAP2 (CDK5RAP2) ELISA试剂盒产品概述

Full name:
CDK5 Regulatory Subunit Associated Protein 2 ELISA试剂盒 (CDK5RAP2)
在www.antibodies-online.cn可供1 CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2) ELISA试剂盒的1不同的供货商。 再加上,我们可以发CDK5RAP2 抗体 (30)和数多这个蛋白质的别的产品。 总共32 CDK5RAP2产品已列进来了。
别名:
2900018K03Rik, an, C48, Cep215, EGFL5, MCPH3, mKIAA1633
list all ELISA KIts 基因 基因ID UniProt
CDK5RAP2 55755 Q96SN8
小鼠 CDK5RAP2 CDK5RAP2 214444 Q8K389
大鼠 CDK5RAP2 CDK5RAP2 286919  

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CDK5RAP2 (CDK5RAP2) ELISA试剂盒 by Reactivity

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适于 CDK5RAP2 相互作用对的更多 ELISA 试剂盒

Human CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2) interaction partners

  1. results suggest that EB1 (显示 MAPRE2 ELISA试剂盒) cooperates with CDK5RAP2 and perhaps other SXIP-containing +TIPs in tracking growing microtubule tips.

  2. CDK5RAP2 may play a role in primary microcephaly and interacts with components of the Hippo signaling pathway

  3. Three siblings with isolated agenesis of corpus callosum carry compound heterozygous variants, p.[Gly94Arg];[Asn1232Ser], in CDK5RAP2 gene.

  4. stabilization of the centrosome-spindle pole interface by the CEP215-HSET (显示 KIFC1 ELISA试剂盒) complex could promote survival of cancer cells containing supernumerary centrosomes.

  5. mouse expresses only one form of CDK5RAP2 that is equivalent to the human and rat alternatively spliced variant forms

  6. These results show that Cep169 targets microtubule tips and regulates stability of microtubules with CDK5RAP2.

  7. Cep68 degradation allows Cep215 removal from peripheral pericentriolar material (PCM (显示 PCMT1 ELISA试剂盒)) preventing centriole separation following disengagement, PCNT (显示 PCNT ELISA试剂盒) cleavage mediates Cep215 removal from core of the PCM (显示 PCMT1 ELISA试剂盒) to inhibit centriole disengagement and duplication

  8. LRRK1 regulates mitotic spindle orientation downstream of PLK1 (显示 PLK1 ELISA试剂盒) through CDK5RAP2-dependent centrosome maturation.

  9. The CEP215-pericentrin (显示 PCNT ELISA试剂盒) interaction is required for centrosome maturation and subsequent bipolar spindle formation during mitosis.

  10. DPP4, CDK5RAP2, and CCR6 are risk loci for rheumatoid arthritis in Han Chinese and congruence with risk variants in Europeans.

Mouse (Murine) CDK5 Regulatory Subunit Associated Protein 2 (CDK5RAP2) interaction partners

  1. mouse expresses only one form of CDK5RAP2 that is equivalent to the human and rat alternatively spliced variant forms

  2. this study revealed the presence of previously unknown splice variants of the Cdk5rap2 gene that are at least in part accountable for the lack of microcephaly in the mice.

  3. In Cdk5rap2-depleted neural embryonic stem cells there is an increase in cell death in differentiating cells.

  4. Mouse expression pattern of CDK5RAP2 is similar to that seen in humans and is in concordance with pathology suggested by neuroimaging studies in humans and mouse

  5. This study demonistrated that CDK5RAP2 is a key molecule that mediates functional interaction and is essential for centrosomal targeting of Aurora-A (显示 AURKA ELISA试剂盒).

  6. These results indicate that CDK5RAP2 is required to maintain centriole engagement and cohesion, thereby restricting centriole replication.

  7. Cdk5rap2 is highly expressed in the neural progenitor pool and its loss results in a depletion of apical progenitors and increased cell-cycle exit leading to premature neuronal differentiation

  8. The an mutation is a genomic inversion of exon 4 of Cdk5rap2, resulting in an in-frame deletion of exon 4 from the mRNA. Cdk5rap2(an/an) neuronal precursors exit the cell cycle prematurely and many undergo apoptosis.

CDK5RAP2 抗原简介

Antigen Summary

This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with CDK5RAP2

  • CDK5 regulatory subunit associated protein 2 (CDK5RAP2) Elisa Kit
  • CDK5 regulatory subunit associated protein 2 (cdk5rap2) Elisa Kit
  • CDK5 regulatory subunit associated protein 2 (Cdk5rap2) Elisa Kit
  • 2900018K03Rik Elisa Kit
  • an Elisa Kit
  • C48 Elisa Kit
  • Cep215 Elisa Kit
  • EGFL5 Elisa Kit
  • MCPH3 Elisa Kit
  • mKIAA1633 Elisa Kit

Protein level used designations for CDK5RAP2

CDK5 regulatory subunit-associated protein 2 , EGF-like-domain, multiple 5 , CDK5 regulatory subunit associated protein 2 , CDK5 regulatory subunit-associated protein 2-like , CDK5 activator-binding protein C48 , centrosomal protein 215 kDa

GENE ID SPECIES
508100 Bos taurus
612705 Canis lupus familiaris
771445 Gallus gallus
100156240 Sus scrofa
733952 Xenopus (Silurana) tropicalis
100071839 Equus caballus
100459050 Pongo abelii
55755 Homo sapiens
214444 Mus musculus
286919 Rattus norvegicus
464695 Pan troglodytes
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