SMAD1 Protein Lysate (GST tagged) (Expressed in bacteria)

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蛋白
  • MLP
  • Xmad1
  • Xsmad1
  • bsp1
  • jv4-1
  • jv41
  • madh1
  • madr1
  • smad-1
  • MADH1
  • fb39h09
  • wu:fb39h09
  • wu:fb97e04
  • 2/23
  • CG12399
  • Dmel\\CG12399
  • E(zen)2
  • En(vvl)
  • MAD
  • Mat
  • P-Mad
  • P-mad
  • PMad
  • Smad
  • Smad1
  • apg
  • c28
  • dMAD
  • dMad
  • l(2)K00237
  • l(2)k00237
  • mad
  • p-Mad
  • pMAD
  • pMad
  • pSmad
  • BSP-1
  • BSP1
  • JV4-1
  • JV41
  • MADR1
  • AI528653
  • Madh1
  • Madr1
  • Mlp1
  • MusMLP
  • smad1
  • xmad
  • SMAD family member 1
  • MAD homolog 1 (Drosophila)
  • Mothers against dpp
  • smad1
  • SMAD1
  • Mad
  • Smad1
  • smad1-a
宿主

资源
大肠杆菌(E. Coli)
标记
GST tag
应用范围
Western Blotting (WB), Control (Ct)
选项
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Supplier Product No.
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产品特性 Partial length SMAD1 is expressed in E. coli.
ProductDetails: Lysate Fraction Whole Cell Lysate
Lysate Type Protein Lysate
别名 SMAD1
背景 The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Alias Symbols: BSP1, JV41, JV4-1, MADH1, MADR1, BSP-1

Protein Interaction Partner: HDAC1, SMURF1, WDR77, AR, UBC, ACVRL1, SMAD4, LEMD3, MAPK1, GSK3B, ZNF521, ZNF423, AKR1B1, AP2A2, PIAS4, ZDHHC3, HBP1, IRF2BP1, SF3B1, MGA, ZNF510, ICK, GMEB1, ZEB2, PUM1, PIGQ, PIAS1, TTF2, KMT2D, ZNF76, XPC, TTF1, SOX5, SNRNP70, SMAD3, SMAD2, SMAD1, INP
分子量 44 kDa
基因ID 4086
NCBI登录号 NM_005900, NP_005891
UniProt Q15797
研究领域 Signaling, Transcription Factors
限制 仅限研究用
状态 Lyophilized
溶解方式 Add 200 μL of distilled water. Final concentration is 1 mg/mL.
浓度 1mg/mL
注意事项 Avoid repeated freeze-thaw cycles.
储存条件 -20 °C
储存方法 For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.