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SensoLyte® AFC Plasmin Activity Assay Kit

Act, FRET Fluorometric
产品编号 ABIN1882541
发货至: 中国
  • 抗原 See all Plasmin 试剂盒
    Plasmin (Plasmin/fibrinolysin (PL/Fbn))
    检测方法
    Fluorometric
    应用范围
    Activation (Act), Fluorescence Resonance Energy Transfer Microscopy (FRET)
    品牌
    SensoLyte®
    产品特性
    The SensoLyte® AFC Plasmin Activity Assay Kit provides a convenient assay for high throughput screening of plasmin inhibitors and inducers or for continuous assay of plasmin activity. The assay utilizes a fluorogenic peptide, which upon enzyme cleavage releases the AFC (7-amido-4-trifluoromethylcoumarin) fluorophore. The fluorescent signal can be measured at Ex/ Em =380 nm/500 nm. This assay can detect picogram level of plasmin activity.
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    Discover our top product Plasmin ELISA Kit
  • 说明

    FRET-based Assay Kit

    限制
    仅限研究用
  • 储存条件
    -80 °C
    储存方法
    Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Protect Components A and B from light and moisture. Components D and F can be stored at room temperature for convenience.
  • Portelli, Siedlinski, Stewart, Postma, Nieuwenhuis, Vonk, Nurnberg, Altmuller, Moffatt, Wardlaw, Parker, Connolly, Koppelman, Sayers: "Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 28, Issue 2, pp. 923-34, (2014) (PubMed).

    Park, Oh, Kim, Cho, Kim: "Identification of a specific haptoglobin C-terminal fragment in arthritic synovial fluid and its effect on interleukin-6 expression." in: Immunology, Vol. 140, Issue 1, pp. 133-41, (2013) (PubMed).

    Stewart, Nijmeh, Brightling, Sayers: "uPAR regulates bronchial epithelial repair in vitro and is elevated in asthmatic epithelium." in: Thorax, Vol. 67, Issue 6, pp. 477-87, (2012) (PubMed).

    Tudpor, Laínez, Kwakernaak, Kovalevskaya, Verkaart, van Genesen, van der Kemp, Navis, Bindels, Hoenderop: "Urinary plasmin inhibits TRPV5 in nephrotic-range proteinuria." in: Journal of the American Society of Nephrology : JASN, Vol. 23, Issue 11, pp. 1824-34, (2012) (PubMed).

  • 抗原
    Plasmin (Plasmin/fibrinolysin (PL/Fbn))
    别名
    Plasmin (Plasmin 产品)
    别名
    plasminogen Kit, PLG Kit
    背景
    Plasmin belongs to the family of serine proteases. It plays a key role in fibrinolysis by dissolving fibrin in blood clots. Besides fibrinolysis, plasmin is also involved in such physiological and pathological processes as wound healing, liver repair, and the maintenance of liver homeostasis.
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