anti-Thrombopoietin (THPO) 抗体产品概述

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anti-Thrombopoietin 抗体 (THPO)
在www.antibodies-online.cn可供175 Thrombopoietin (THPO) 抗体的25不同的供货商。 再加上,我们可以发Thrombopoietin 蛋白 (73)Thrombopoietin 试剂盒 (72)和数多这个蛋白质的别的产品。 总共335 Thrombopoietin产品已列进来了。
别名:
LOC100231762, Mgdf, MKCSF, Ml, Mpllg, THCYT1, Tpo, Tpo1, Tpo2, Tpo3, Tpo4

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引用最多的anti-Thrombopoietin 抗体

  1. Human Polyclonal Thrombopoietin Primary Antibody for EIA, WB - ABIN359714 : Baker, Su, Hsu, Shi, Zhao, Strande, Fu, Xu, Eis, Komorowski, Jensen, Tweddell, Rafiee, Gross: Human thrombopoietin reduces myocardial infarct size, apoptosis, and stunning following ischaemia/reperfusion in rats. in Cardiovascular research 2008 (PubMed)
    Show all 3 references for 359714

  2. Human Monoclonal Thrombopoietin Primary Antibody for FACS, ELISA - ABIN969571 : Graziano, Carone, Panza, Marino, Magini, Romeo, Pession, Seri: Association of hereditary thrombocythemia and distal limb defects with a thrombopoietin gene mutation. in Blood 2009 (PubMed)
    Show all 2 references for 969571

  3. Human Monoclonal Thrombopoietin Primary Antibody for EIA, WB - ABIN1109245 : Eissa, Gad, Rabie, El-Gayar: Thrombopoietin level in patients with chronic liver diseases. in Annals of hepatology 2008 (PubMed)
    Show all 2 references for 1109245

  4. Dog (Canine) Polyclonal Thrombopoietin Primary Antibody for WB - ABIN2787808 : Baker, Gray, Wright, Fitzsimons, Nimmo, Lowry, Mutrie,: The effect of a pedometer-based community walking intervention "Walking for Wellbeing in the West" on physical activity levels and health outcomes: a 12-week randomized controlled trial. in The international journal of behavioral nutrition and physical activity 2008 (PubMed)
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  5. Human Polyclonal Thrombopoietin Primary Antibody for EIA, Func - ABIN116255 : Xie, Chan, Johnson, Starr, McCarthy, Kapur, Yoder: Thrombopoietin promotes mixed lineage and megakaryocytic colony-forming cell growth but inhibits primitive and definitive erythropoiesis in cells isolated from early murine yolk sacs. in Blood 2003 (PubMed)

  6. Human Polyclonal Thrombopoietin Primary Antibody for WB - ABIN391802 : Kanayasu-Toyoda, Ishii-Watabe, Suzuki, Oshizawa, Yamaguchi: A new role of thrombopoietin enhancing ex vivo expansion of endothelial precursor cells derived from AC133-positive cells. in The Journal of biological chemistry 2007 (PubMed)

  7. Human Polyclonal Thrombopoietin Primary Antibody for IF (p), IHC (p) - ABIN1714401 : Nakamura-Ishizu, Takubo, Kobayashi, Suzuki-Inoue, Suda: CLEC-2 in megakaryocytes is critical for maintenance of hematopoietic stem cells in the bone marrow. in The Journal of experimental medicine 2015 (PubMed)

更多抗Thrombopoietin的相互作用对抗体

Zebrafish Thrombopoietin (THPO) interaction partners

  1. These studies indicate that the functional role of Tpo in the differentiation of thrombocytes from hematopoietic stem and progenitor cells is well conserved among vertebrate organisms, positing the zebrafish as an excellent model to investigate diseases caused by dysregulated erythro- and thrombo-poietic differentiation.

Human Thrombopoietin (THPO) interaction partners

  1. Genetically engineered mesenchymal stromal cells produce IL-3 (显示 IL-3 抗体) and TPO to further improve human scaffold-based xenograft models

  2. bone marrow megakaryocytes possess a complete mechanism to synthesize the ECM (显示 MMRN1 抗体) components, and that thrombopoietin is a pivotal regulator of this new function inducing transforming growth factor-b1 (TGF-beta1 (显示 TGFB1 抗体)) release and consequent activation of the downstream pathways, both in vitro and in vivo

  3. High Thrombopoietin expression is associated with immune thrombocytopenia in pregnancy.

  4. Colorectal cancer tumor-initiating cells (TICs) expressing CD110 (显示 MPL 抗体), the thrombopoietin (TPO)-binding receptor, mediate liver metastasis. We show that TPO promotes metastasis of CD110 (显示 MPL 抗体)+ TICs to the liver by activating lysine degradation.

  5. decreased TPO levels or decreased bone marrow production of platelets may not be a cause of thrombocytopenia in chronic hepatitis C

  6. WASP (显示 WASL 抗体), RUNX1 (显示 RUNX1 抗体), and ANKRD26 (显示 ANKRD26 抗体) genes are important for normal TPO signaling and the network underlying thrombopoiesis.

  7. Data suggest that elevated serum level of thrombopoietin may serve as unfavorable marker of stage of multiple myeloma.

  8. The regulation of OCs by TPO highlights a novel therapeutic target for bone loss diseases and may be important to consider in the numerous hematologic disorders associated with alterations in TPO/c-mpl (显示 MPL 抗体) signaling

  9. TPO was greatly enhanced in HPT in comparison with ITP (显示 ITPA 抗体) patients (958 +/- 659 and 11 +/- 27 pg/ml, p < 0.001). In the ITP (显示 ITPA 抗体) group a reverse correlation was detected between TPO and glycocalicin (r = -0.373, p = 0.006).

  10. observations suggest that NRP-1 (显示 NELL1 抗体) is involved in megakaryocytopoiesis through complex formation with PDGFRs, and that NRP-1 (显示 NELL1 抗体)-PDGFR (显示 PDGFRB 抗体)-complexes may contribute to effective cellular functions mediated by TPO and PDGF (显示 PDGFA 抗体) in megakaryocytic cells

Cow (Bovine) Thrombopoietin (THPO) interaction partners

  1. The results demonstrate the possible involvement of locally produced TPO (显示 TPO 抗体)/c-MPL (显示 MPL 抗体) system as a 'physiological filter' in bovine ovary where they may promote cell selection by inducing proliferation of viable cells and scavenging non-viable cells.

Mouse (Murine) Thrombopoietin (THPO) interaction partners

  1. Thrombopoietin-mediated phosphorylation of STAT5 (显示 STAT5A 抗体) triggers its genome-wide relocation to STAT (显示 STAT1 抗体) consensus sites, resulting in loss of a uSTAT5 program that restrains megakaryocytic differentiation and activation of STAT5 (显示 STAT5A 抗体)-driven gene expression.

  2. Furthermore, although the contribution of the TPO treated graft to long-term hematological engraftment was reduced, the TPO treated and untreated grafts both contributed significantly to long-term chimerism in vivo.

  3. TPO treatment also promoted the peripheral induction of Foxp3 (显示 FOXP3 抗体)(+) Tregs in conjunction with elevated circulating TGF-beta (显示 TGFB1 抗体) levels.

  4. novel findings about aspects of TPO action on stem cells

  5. Mpl (显示 MPL 抗体) expression, but not Tpo, is fundamental in the development of JAK2V617F(+) myeloproliferative neoplasms

  6. Thrombopoietin/MPL (显示 MPL 抗体) signaling confers growth and survival capacity to CD41-positive cells in a mouse model of Evi1 (显示 MECOM 抗体) leukemia.

  7. Megakaryocytes regulate cell cycle quiescence of hematopoietic stem cell through the production of thrombopoietin.

  8. IEX-1 (显示 IER3 抗体) has a role in activation of Erk (显示 EPHB2 抗体) and NF-kB pathways, which affects thrombopoietin-promoted NHEJ DNA repair in hematopoietic stem cells

  9. Findings establish that Clock regulates Thpo and Mpl (显示 MPL 抗体) expression in vivo, and demonstrate an important link between the body's circadian timing mechanisms and megakaryopoiesis.

  10. Signal transduction pathway of ERK1/2 (显示 MAPK1/3 抗体) participates in the activation of thrombopoietin in inflammatory injury of BV2 (显示 DNAH9 抗体) cells.

Thrombopoietin (THPO) 抗原简介

Antigen Summary

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternate splicing results in multiple transcript variants of this gene.

Alternative names and synonyms associated with Thrombopoietin (THPO)

  • thrombopoietin (THPO) 抗体
  • thrombopoietin (thpo) 抗体
  • thrombopoietin (LOC100231762) 抗体
  • thrombopoietin (Thpo) 抗体
  • thrombopoietin-like (LOC100620258) 抗体
  • thrombopoietin-like (LOC100357079) 抗体
  • thrombopoietin-like (LOC100855822) 抗体
  • LOC100231762 抗体
  • Mgdf 抗体
  • MKCSF 抗体
  • Ml 抗体
  • Mpllg 抗体
  • THCYT1 抗体
  • Tpo 抗体
  • Tpo1 抗体
  • Tpo2 抗体
  • Tpo3 抗体
  • Tpo4 抗体

Protein level used designations for anti-Thrombopoietin (THPO) 抗体

thrombopoietin (myeloproliferative leukemia virus oncogene ligand, megakaryocyte growth and development factor) , thrombopoietin , MPL ligand , c-mpl ligand , megakaryocyte colony-stimulating factor , megakaryocyte growth and development factor , megakaryocyte stimulating factor , myeloproliferative leukemia virus oncogene ligand , thrombopoietin nirs variant 1 , C-mpl ligand

GENE ID SPECIES
736549 Pan troglodytes
100189608 Danio rerio
100231762 Taeniopygia guttata
100302539 Felis catus
100582097 Nomascus leucogenys
7066 Homo sapiens
538672 Bos taurus
21832 Mus musculus
81811 Rattus norvegicus
414803 Gallus gallus
607489 Canis lupus familiaris
100726592 Cavia porcellus
101119601 Ovis aries
100620258 Sus scrofa
100357079 Oryctolagus cuniculus
100855822 Canis lupus familiaris
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