STAT5A (STAT5A) ELISA试剂盒产品概述

Full name:
Signal Transducer and Activator of Transcription 5A ELISA试剂盒 (STAT5A)
在www.antibodies-online.cn可供43 Signal Transducer and Activator of Transcription 5A (STAT5A) ELISA试剂盒的13不同的供货商。 再加上,我们可以发STAT5A 抗体 (497)STAT5A 蛋白 (11)和数多这个蛋白质的别的产品。 总共594 STAT5A产品已列进来了。
别名:
AA959963, MGF, Stat5, STAT5A, STAT5A/MGF, STATA5

引用最多的STAT5A ELISA试剂盒

  1. Human STAT5A ELISA Kit for Cell ELISA - ABIN1981843 : Park, Lee, Frank, Razani, Nguyen, Parlow, Russell, Hulit, Pestell, Lisanti: Caveolin-1-deficient mice show accelerated mammary gland development during pregnancy, premature lactation, and hyperactivation of the Jak-2/STAT5a signaling cascade. in Molecular biology of the cell 2002 (PubMed)
    Show all 3 references for 1981843

适于 STAT5A 相互作用对的更多 ELISA 试剂盒

Human Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

  1. Molecular interactions of EphA4 (显示 EPHA4 ELISA试剂盒), growth hormone receptor (显示 GHR ELISA试剂盒), Jak2 (显示 JAK2 ELISA试剂盒), and STAT5B (显示 STAT5B ELISA试剂盒) have been described.

  2. High STAT5 phosphorylation is associated with systemic lupus erythematosus.

  3. NPM1 (显示 NPM1 ELISA试剂盒) downregulation by P-STAT5 is mediated by impairing the BRCA1-BARD1 (显示 BARD1 ELISA试剂盒) ubiquitin ligase, which controls the stability of NPM1 (显示 NPM1 ELISA试剂盒). In turn, decreased NPM1 (显示 NPM1 ELISA试剂盒) levels led to suppression of p53 (显示 TP53 ELISA试剂盒) expression, resulting in enhanced cell survival.

  4. All merkel cell carcinoma (MCC) cases with a good outcome expressed pSTAT5B, whereas all MCC cases with a poor outcome did not express pSTAT5B; hence, pSTAT5B expression may be an indicator of positive prognosis in patients with MCC.

  5. High STAT5A expression is associated with B-lymphoblastic lymphoma with inflammation.

  6. Results provide evidence that HDAC6 (显示 HDAC6 ELISA试剂盒) could regulate HMGN2 (显示 HMGN2 ELISA试剂盒) acetylation levels and binding to Stat5a-responsive promoters, and therefore, Stat5a transcriptional activity in breast cancer cells.

  7. Sustained STAT5 transcription factor (STAT5) phosphorylation is necessary to induce long-term interleukin 2 receptor subunit alpha (CD25 (显示 IL2RA ELISA试剂盒)) expression in T lymphocytes.

  8. BCR/ABL (显示 ABL1 ELISA试剂盒) positively regulates the expression of EZH2 (显示 EZH2 ELISA试剂盒) via STAT5 signaling.

  9. these results demonstrate that the oncogenic signal transducer and activator of transcription 5/Akt (显示 AKT1 ELISA试剂盒) pathway is a cellular target for indole-3-carbinol in chronic myeloid leukemia (显示 BCL11A ELISA试剂盒) cells. Thus, this clinically tested natural compound can be a potential candidate in the treatment of chronic myeloid leukemia (显示 BCL11A ELISA试剂盒) following confirmation with clinical studies

  10. elucidate a novel mechanism whereby the linker histone H1 (显示 H1F0 ELISA试剂盒) prevents STAT5 binding at promoter DNA, and the PRL (显示 PRL ELISA试剂盒)-induced dissociation of H1 mediated by HMGN2 (显示 HMGN2 ELISA试剂盒) is necessary to allow full STAT5 recruitment and promote the biological effects of PRL (显示 PRL ELISA试剂盒) signaling

Mouse (Murine) Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

  1. STAT5 target genes such as Oncostatin M (显示 OSM ELISA试剂盒) were highly expressed in FLT3 (显示 FLT3 ELISA试剂盒)-ITD(+) myeloid but not in FLT3 (显示 FLT3 ELISA试剂盒)-ITD(+) lymphoid progenitor cells; lineage-specific STAT5 activation in hematopoietic progenitor cells predicts the FLT3 (显示 FLT3 ELISA试剂盒)(+)-mediated leukemic phenotype in mice.

  2. findings reveal an essential role for STAT5 in maintaining lipid homeostasis in white adipose tissue and provide a rationale for future studies into the potential of STAT5 manipulation to improve outcomes in metabolic diseases.

  3. deregulation of local signal transducer and activator of transcription 5 signaling augments high fat diet-induced lipid accumulation in both muscle and liver.

  4. Data show that CUZD1 (显示 CUZD1 ELISA试剂盒) interacts with a complex containing JAK1 (显示 JAK1 ELISA试剂盒)/JAK2 (显示 JAK2 ELISA试剂盒) and STAT5, downstream transducers of prolactin (显示 PRL ELISA试剂盒) signaling in the mammary gland.

  5. The study describes an interaction network of STAT5a/LSD1 (显示 KDM1A ELISA试剂盒)/HDAC3 (显示 HDAC3 ELISA试剂盒) and a dual function of LSD1 (显示 KDM1A ELISA试剂盒)/HDAC3 (显示 HDAC3 ELISA试剂盒) on STAT5a-dependent transcription, defined by protein-protein interactions, genomic binding localization/affinity and motifs.

  6. this study shows that lipoxin A4 protects against LPS (显示 TLR4 ELISA试剂盒)-induced sepsis by promoting the generation and migration of splenic innate response activator B cells, and the underlying molecular mechanism may be related to STAT5 activation

  7. Study showed that suppression of STAT3 (显示 STAT3 ELISA试剂盒), STAT5, and STAT6 (显示 STAT6 ELISA试剂盒) and overexpression of the proapoptotic factor STAT1 (显示 STAT1 ELISA试剂盒), which provides p53 (显示 TP53 ELISA试剂盒)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (显示 ERBB2 ELISA试剂盒) tyrosine kinase receptor (显示 KDR ELISA试剂盒) overexpression promotes neuronal survival through activation of STAT (显示 STAT1 ELISA试剂盒)-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1 (显示 STAT1 ELISA试剂盒)

  8. Mechanistically, RL negatively regulates Stat5 phosphorylation and Elf5 (显示 ELF5 ELISA试剂盒) expression at the onset of lactogenesis. Continuous RL exposure leads to the expansion of basal and bipotent cells in WT and MMTV-RANK acini. Overall, we demonstrate that enhanced Rank signaling impairs secretory differentiation during pregnancy by inhibition of the prolactin (显示 PRL ELISA试剂盒)/p-Stat5 pathway.

  9. Bcl6 (显示 BCL6 ELISA试剂盒) promoted T follicular helper cell differentiation through antagonizing IL-7R / STAT5a axis.

  10. constitutive STAT5 binding to c-Myc (显示 MYC ELISA试剂盒) super-enhancer might contribute to BRD2 (显示 BRD2 ELISA试剂盒) maintenance and thus allow sustained expression of c-Myc (显示 MYC ELISA试剂盒) in Ba/F3 cells transformed by STAT5-1*6.

Pig (Porcine) Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

Cow (Bovine) Signal Transducer and Activator of Transcription 5A (STAT5A) interaction partners

  1. There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system.

  2. Milk production traits were analyzed for each animal in the first, second, third, and fourth lactation. No genetic variability was found at STAT5A/AvaI locus. At STAT5A/MslI locus, the frequencies of T and C alleles were 0.875 and 0.125, respectively. Significant differences between genotypes were found

  3. Results indicate that SNPs in STAT5A and JAK2 (显示 JAK2 ELISA试剂盒) genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  4. The embryonic STAT5A gene is primarily activated by maternal gene products and the most abundant STAT5A expression occurred at the 2-cell stage blastocysts.

  5. INVESTIGATION OF STAT5A, FSHR (显示 FSHR ELISA试剂盒) AND LHR (显示 LHCGR ELISA试剂盒) GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS

  6. The Stat5a gene is associated with an increase in lactation of mammary gland epithelial cells.

  7. STAT5A/AvaI polymorphism seems to be a promising indirect marker to improve milk production traits in cattle.

  8. Associations between reproduction and milk traits, and polymorphisms at the STAT5A and FGF2 (显示 FGF2 ELISA试剂盒) gene loci, were found with STAT5A polymorphism for age at first calving (suggestive effect; P =0.077) and lactation milk yield (significant effect; P<0.05).

  9. Base sequence variation in STAT5A-noncoding region was studied.

  10. The association of fertilization rate with STAT5A polymorphisms was evaluated in ocytes. Associations were found for 6 and 2 SNP. 5 SNP showed associations with both embryonic survival and fertilization rate compared with 1 SNP.

STAT5A 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL.

Alternative names and synonyms associated with STAT5A

  • signal transducer and activator of transcription 5A (STAT5A) Elisa Kit
  • signal transducer and activator of transcription 5A (Stat5a) Elisa Kit
  • signal transducer and activator of transcription 5A-like (LOC100348518) Elisa Kit
  • signal transducer and activator of transcription 5B (STAT5B) Elisa Kit
  • AA959963 Elisa Kit
  • MGF Elisa Kit
  • Stat5 Elisa Kit
  • STAT5A Elisa Kit
  • STAT5A/MGF Elisa Kit
  • STATA5 Elisa Kit

Protein level used designations for STAT5A

signal transducer and activator of transcription 5A , signal transducer and activator of transcription 5A-like , mammary gland factor STAT5A , mammary gland factor , signal transducer and activator of transcription 5 , STAT5A, Mammary Gland Factor , transcription factor STAT5B

GENE ID SPECIES
100052904 Equus caballus
454681 Pan troglodytes
574129 Macaca mulatta
100461695 Pongo abelii
6776 Homo sapiens
20850 Mus musculus
24918 Rattus norvegicus
490968 Canis lupus familiaris
397550 Sus scrofa
282375 Bos taurus
100716811 Cavia porcellus
443419 Ovis aries
100348518 Oryctolagus cuniculus
6777 Homo sapiens
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