STAT4 (STAT4) ELISA试剂盒产品概述

Full name:
Signal Transducer and Activator of Transcription 4 ELISA试剂盒 (STAT4)
在www.antibodies-online.cn可供39 Signal Transducer and Activator of Transcription 4 (STAT4) ELISA试剂盒的13不同的供货商。 再加上,我们可以发STAT4 抗体 (290)STAT4 蛋白 (8)和数多这个蛋白质的别的产品。 总共357 STAT4产品已列进来了。
别名:
SLEB11
list all ELISA KIts 基因 基因ID UniProt
STAT4 6775 Q14765
STAT4 20849 P42228
STAT4 367264  

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引用最多的STAT4 ELISA试剂盒

  1. Human STAT4 ELISA Kit for Cell ELISA - ABIN1981841 : Kaplan, Sun, Hoey, Grusby: Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice. in Nature 1996 (PubMed)
    Show all 11 references for 1981841

适于 STAT4 相互作用对的更多 ELISA 试剂盒

Human Signal Transducer and Activator of Transcription 4 (STAT4) interaction partners

  1. Results found that activated STAT4 was overexpressed in epithelial cells of ovarian cancer and provide evidence that it promotes ovarian cancer metastasis via tumor-derived Wnt7a (显示 WNT7A ELISA试剂盒)-induced activation of cancer-associated fibroblasts.

  2. STAT4 rs7574865 gene polymorphism is associated with the susceptibility of primary biliary cirrhosis in the Han population of Jiangsu province.

  3. The findings results confirm the important role of STAT4 gene in the predisposition to Systemic sclerosis and its phenotypes, such as the presence of Interstitial Lung disease , cardiac injury , and seropositivity for anti-topoisomerase I (显示 TOP1 ELISA试剂盒) antibodies in the Russian population.

  4. results show specific and dominant contribution of STAT4 in the hematopoietic compartment to metabolic health and inflammation in diet-induced obesity.

  5. reported that SNPs in STAT4, PTPN2 (显示 PTPN2 ELISA试剂盒), PSORS1C1, and TRAF3IP2 (显示 TRAF3IP2 ELISA试剂盒) are associated with response to TNF (显示 TNF ELISA试剂盒)-i treatment in RA patients; however, these findings should be validated in a larger population

  6. This is the first demonstration of STAT4 acting as a transcriptional repressor in response to IFN-alpha (显示 IFNA ELISA试剂盒)/beta signaling and highlights the unique activity of this cytokine to acutely block the expression of an inflammatory cytokine in human T cells.

  7. A higher risk to develop RA was observed for rs7574865 in the STAT-4 gene, while the rs1800872 in the IL-10 (显示 IL10 ELISA试剂盒) gene showed a protective effect.

  8. STAT4 rs7574865 polymorphism has a role in rheumatoid arthritis and disease activity, but not in anti-CCP (显示 CRYGD ELISA试剂盒) antibody levels in a Mexican population

  9. this study shows that STAT4 single nucleotide polymorphism affects clinical outcomes of pediatric acute leukemia patients after hematopoietic stem cell transplant

  10. this study shows that STAT4 gene polymorphisms are associated with ankylosing spondylitis in Southwest China

Mouse (Murine) Signal Transducer and Activator of Transcription 4 (STAT4) interaction partners

  1. STAT4 has a pro-atherogenic role that is at least partially independent of Th1 (显示 HAND1 ELISA试剂盒) cell-derived interferon-gamma (显示 IFNG ELISA试剂盒)

  2. Modulation of IL-12 (显示 IL12A ELISA试剂盒)/STAT4 signaling may be a valuable therapeutic strategy to preserve islet/beta-cell viability in established diabetes

  3. This study found that stathmin (显示 STMN1 ELISA试剂盒) plays an important role in adult hippocampal neurogenesis and spinogenesis. In addition, stathmin (显示 STMN1 ELISA试剂盒) mutation led to impaired NMDA receptor-dependent and neurogenesis-associated memory

  4. STAT4 controls GM-CSF (显示 CSF2 ELISA试剂盒) production by both Th1 (显示 HAND1 ELISA试剂盒) and Th17 cells during experimental autoimmune encephalomyelitis.

  5. Data (including data from studies in knockout mice) suggest Stat4 deletion reduces inflammation in peri (显示 POSTN ELISA试剂盒)-vascular and visceral adipose tissue and this appears to contribute via direct or indirect effects to reduced atheroma formation.

  6. T-bet- and STAT4-dependent IL-33 (显示 IL33 ELISA试剂盒) receptor expression have roles in directly promoting antiviral Th1 (显示 HAND1 ELISA试剂盒) cell responses

  7. Primary infections of mice with lymphocytic choriomeningitis virus (LCMV) demonstrated that T cell receptor stimulation induced responsiveness for IFN-gamma (显示 IFNG ELISA试剂盒) and CD25 (显示 IL2RA ELISA试剂盒) induction through STAT4-independent pathways.

  8. STAT4 appears to be a critical transcription factor in defense against mycobacterial infection

  9. STAT4 deficiency protects against neointima formation following arterial injury in mice.

  10. IL-12 (显示 IL12A ELISA试剂盒) drives small airway remodeling via STAT4 signaling.

Cow (Bovine) Signal Transducer and Activator of Transcription 4 (STAT4) interaction partners

  1. These results suggest that the 2 single nucleotide polymorphisms of STAT4 could be used as genetic markers for milk performance traits in Chinese Holstein cows.

STAT4 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.

Alternative names and synonyms associated with STAT4

  • signal transducer and activator of transcription 4 (STAT4) Elisa Kit
  • signal transducer and activator of transcription 4 (stat4) Elisa Kit
  • signal transducer and activator of transcription 4 (Stat4) Elisa Kit
  • SLEB11 Elisa Kit

Protein level used designations for STAT4

signal transducer and activator of transcription 4

GENE ID SPECIES
100054693 Equus caballus
100380385 Salmo salar
100617910 Monodelphis domestica
6775 Homo sapiens
20849 Mus musculus
367264 Rattus norvegicus
768406 Gallus gallus
478845 Canis lupus familiaris
397261 Sus scrofa
515988 Bos taurus
100344146 Oryctolagus cuniculus
100726892 Cavia porcellus
101117562 Ovis aries
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