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Human STAT3 ELISA Kit for Cell ELISA - ABIN1981839
Kanai, Konda, Nakajima, Izumi, Kanda, Nanakin, Kubohara, Chiba: Differentiation-inducing factor-1 (DIF-1) inhibits STAT3 activity involved in gastric cancer cell proliferation via MEK-ERK-dependent pathway. in Oncogene 2003
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Human STAT3 ELISA Kit for Sandwich ELISA - ABIN625232
Sharma, Yang, Xi, Grotta, Aronowski, Savitz: IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways. in Brain research 2011
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Human STAT3 ELISA Kit for Sandwich ELISA - ABIN625245
Tukaj, Grüner, Tukaj, Zillikens, Kasperkiewicz: Calcitriol exerts anti-inflammatory effects in keratinocytes treated with autoantibodies from a patient with bullous pemphigoid. in Journal of the European Academy of Dermatology and Venereology : JEADV 2015
Stat3 regulates self-renewal of adult muscle satellite cells during injury-induced muscle regeneration through various partners, such as Pax7 (显示 PAX7 ELISA试剂盒).
cytokine-activated STAT3 and STAT6 cooperate in macrophages to promote a secretory phenotype that enhances tumor progression in a cathepsin-dependent manner.
this study shows that the upregulation of IL-10Ra (显示 IL10RA ELISA试剂盒) by STAT3 contributed to the suppressive function of dendritic cellss following histone deacetylase (显示 HDAC1 ELISA试剂盒) inhibition
APPL1 (显示 APPL1 PLURAL_@2013@)-SirT1 (显示 SIRT1 PLURAL_@2013@)-STAT3 pathway mediated adiponectin (显示 ADIPOQ PLURAL_@2013@) signaling in primary hepatocytes.
HDL (显示 HSD11B1 ELISA试剂盒)-associated sphingosine 1-phosphate inhibits macrophage apoptosis by stimulating STAT3 activity and survivin (显示 BIRC5 ELISA试剂盒) expression.
loss of Fyn (显示 FYN ELISA试剂盒) in the kidney prevents unilateral ureteral obstruction-induced tubulointerstitial fibrosis, mediated by a reduction in STAT3 phosphorylation
Results provide genetic evidence indicating that mTOR (显示 FRAP1 ELISA试剂盒) and Raptor (显示 RPTOR ELISA试剂盒) are required for sensory axon regeneration enhanced by peripheral lesions in mice, whereas Rictor (显示 RICTOR ELISA试剂盒) plays a minor role. The peripheral lesion activates rapamycin-resistant mTOR (显示 FRAP1 ELISA试剂盒) signaling to modulate Stat3 activity and further promotes axon regeneration.
These data describe a novel regulatory mechanism through which STAT3 and the Ikaros (显示 IKZF1 ELISA试剂盒) zinc finger transcription factors Aiolos (显示 IKZF3 ELISA试剂盒) and Ikaros (显示 IKZF1 ELISA试剂盒) cooperate to regulate Bcl-6 (显示 BCL6 ELISA试剂盒) expression.
Transplantation from GRIM19 (显示 NDUFA13 ELISA试剂盒)-overexpressing cells downregulated the expression of nuclear factor of activated T cells (NFATc1 (显示 NFATC1 ELISA试剂盒)) but promoted the expression of regulator of calcineurin (RCAN)3 (显示 RCAN3 ELISA试剂盒) while downregulating NFAT (显示 NFATC1 ELISA试剂盒)-dependent cytokine gene expression.
Data suggest MHV68 RTA (显示 RBM9 ELISA试剂盒) specifically recognizes and recruits activated (phosphorylated at Tyr705) host Stat3 during lytic phase of infection; Stat3, once phosphorylated at Tyr705, avidly binds consensus target site in promoters of regulated genes. (MHV68 = murine gammaherpesvirus 68; RTA (显示 RBM9 ELISA试剂盒) = replication and transcription activator coded for by ORF50; Stat3 = signal transducer and activator of transcription 3 protein)
High STAT3 expression is associated with recurrence in Glioma.
IL-27 (显示 IL27 ELISA试剂盒) stimulation activated STAT1 (显示 STAT1 ELISA试剂盒) and STAT3 in HeLa and T98G cells, suggesting that IL-27 (显示 IL27 ELISA试剂盒) engages the STAT1 (显示 STAT1 ELISA试剂盒)/3 pathway, which then leads to the upregulation of IL-6 (显示 IL6 ELISA试剂盒), IP-10 (显示 CXCL10 ELISA试剂盒), and MIG (显示 CXCL9 ELISA试剂盒)
STAT3 and ATG12 (显示 ATG12 ELISA试剂盒) are targets of miR (显示 MLXIP ELISA试剂盒)-454-3p.
luteolin inhibited STAT3 activation through disrupting the binding of HSP-90 to STAT3, which promoted its interaction to SHP-1.
High STAT3 expression is associated with B-cell lymphoma.
PAI-1 (显示 SERPINE1 ELISA试剂盒) was identified as the target gene of miR (显示 MLXIP ELISA试剂盒)-34a and activated the Stat3 signaling pathway to promote epithelial-mesenchymal transition in non-small cell lung cancer cells.
These results suggest that miR146a may regulate SOCS1 (显示 SOCS1 ELISA试剂盒)/STAT3 and cytokine signalling in monocytes, directing T-cell differentiation and balancing immune clearance and immune injury during chronic viral infection.
High STAT3 expression is associated with neuroblastoma (显示 ARHGEF16 ELISA试剂盒).
simvastatin also increased p21 (显示 CDKN1A ELISA试剂盒) and p27 (显示 PAK2 ELISA试剂盒) expression in tumor sections by reducing Skp2 expression and inducing AMPK (显示 PRKAA1 ELISA试剂盒) activation and STAT3 suppression in the same tumor tissues.
Overexpression of REP1 (显示 CHM ELISA试剂盒) in BEAS-2B cells enhanced cell growth and anchorage-independent colony formation with little increase in EGFR (显示 EGFR ELISA试剂盒) level and STAT3 activation.
STA3 (显示 ARHGEF3 ELISA试剂盒) facilitates TLR4 (显示 TLR4 ELISA试剂盒)-dependent IL-6 (显示 IL6 ELISA试剂盒) and IL-8 (显示 IL8 ELISA试剂盒) production via IL-6 (显示 IL6 ELISA试剂盒) receptor-positive feedback in endometrial cells.
STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.
Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate
results show for the first time that interleukin-6 (显示 IL6 ELISA试剂盒) (IL), in the presence of its soluble receptor (显示 IFNAR1 ELISA试剂盒) (sIL (显示 STIL ELISA试剂盒)-6R), induces activation of JAK1 (显示 JAK1 ELISA试剂盒), JAK2 (显示 JAK2 ELISA试剂盒), and STAT1 (显示 STAT1 ELISA试剂盒)/STAT3 proteins in bovine articular chondrocytes
peroxynitrite causes increased expression of VEGF (显示 VEGFA ELISA试剂盒) in vascular endothelial cells by a process that requires the activation of STAT3
Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (显示 NOX1 ELISA试剂盒)-mediated activation of STAT3.
this study shows that weaning caused severe inflammation associated with activation of the STAT3 pathway in the jejunum of piglets
maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 (显示 CCND2 ELISA试剂盒) and PSEN1 (显示 PSEN1 ELISA试剂盒) genes via a STAT3-dependent pathway
Studied effect of recombinant porcine leukemia inhibitory factor (显示 LIF ELISA试剂盒) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (显示 FTH1 ELISA试剂盒)-supplemented media.
Data suggest that IL-6 (interleukin 6 (显示 IL6 ELISA试剂盒)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (显示 IL6 ELISA试剂盒)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).
the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.
Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.
STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways
Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.
This is the first report of the genetic polymorphisms of the JAK1 (显示 JAK1 ELISA试剂盒) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.
Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.
Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (显示 MMP2 ELISA试剂盒) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.
Stat3 regulates cell proliferation and axis extension in part via upregulation of Cdc25a (显示 CDC25A ELISA试剂盒) expression during oogenesis. Accordingly, restoring Cdc25a (显示 CDC25A ELISA试剂盒) expression in stat3 mutants partially suppressed cell proliferation and gastrulation defects.
PTPN9 (显示 PTPN9 ELISA试剂盒) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (显示 GATA1 ELISA试剂盒) and ZBP-89 (显示 ZNF148 ELISA试剂盒).
Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.
Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.
This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.
The results of this study suggested that the stat3/socs3 (显示 SOCS3 ELISA试剂盒) pathway is a key response in all tissue regeneration in zebrafish.
stat3, a known oncogene (显示 RAB1A ELISA试剂盒) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.
Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (显示 PRCP ELISA试剂盒) in neighboring cells during zebrafish gastrulation.
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.
signal transducer and activator of transcription 3 (acute-phase response factor)
, signal transducer and activator of transcription 3
, signal transduction and activation of transcription 3
, Signal transducer and activator of transcription 3
, signal transducer and activator of transcription 3-like
, acute phase response factor
, acute-phase response factor
, DNA-binding protein APRF
, Protein Stat3
, signal transducer and activator of transcription 3.1
, stat 3