anti-STAT3 (STAT3) 抗体产品概述

Full name:
anti-Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) 抗体 (STAT3)
在www.antibodies-online.cn可供637 Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) 抗体的40不同的供货商。 再加上,我们可以发STAT3 试剂盒 (62)STAT3 蛋白 (34)和数多这个蛋白质的别的产品。 总共761 STAT3产品已列进来了。
别名:
1110034C02Rik, aprf, AW109958, hies, stat3, wu:fc15d02, wu:fl59g06, Xstat3, z-Stat3

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引用最多的anti-STAT3 抗体

  1. Human Polyclonal STAT3 Primary Antibody for IHC (p), WB - ABIN389665 : Schick, Oakeley, Hynes, Badache: TEL/ETV6 is a signal transducer and activator of transcription 3 (Stat3)-induced repressor of Stat3 activity. in The Journal of biological chemistry 2004 (PubMed)
    Show all 8 references for 389665

  2. Human Polyclonal STAT3 Primary Antibody for EIA, IHC (p) - ABIN358234 : Wang, Wang, Zhang, Huang, Liao, Fuller: Analysis of the activation status of Akt, NFkappaB, and Stat3 in human diffuse gliomas. in Laboratory investigation; a journal of technical methods and pathology 2004 (PubMed)
    Show all 5 references for 358234

  3. Cow (Bovine) Polyclonal STAT3 Primary Antibody for IF, IHC - ABIN2780479 : Ohbayashi, Kawakami, Muromoto, Togi, Ikeda, Kamitani, Sekine, Honjoh, Matsuda: The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 4 references for 2780479

  4. Human Polyclonal STAT3 Primary Antibody for FACS, IF (p) - ABIN738261 : Yang, Sun, Sun, Qi: Effect of suppressor of cytokine signaling 2 (SOCS2) on fat metabolism induced by growth hormone (GH) in porcine primary adipocyte. in Molecular biology reports 2012 (PubMed)
    Show all 3 references for 738261

  5. Cow (Bovine) Polyclonal STAT3 Primary Antibody for IHC, WB - ABIN2792239 : Suen, Uddin, Prow, Bowen, Hall, Bielefeldt-Ohmann: Tissue-specific transcription profile of cytokine and chemokine genes associated with flavivirus control and non-lethal neuropathogenesis in rabbits. in Virology 2016 (PubMed)
    Show all 2 references for 2792239

  6. Human Polyclonal STAT3 Primary Antibody for ELISA, WB - ABIN185692 : Palmqvist, Glover, Hsu, Lu, Bossen, Piret, Humphries, Helgason: Correlation of murine embryonic stem cell gene expression profiles with functional measures of pluripotency. in Stem cells (Dayton, Ohio) 2005 (PubMed)

  7. Human Polyclonal STAT3 Primary Antibody for IF (p), IHC (p) - ABIN746198 : Song, Sun, Liu, Liu, Chen, Zhang, Zheng, Zhang: STAT3, p-STAT3 and HIF-1α are associated with vasculogenic mimicry and impact on survival in gastric adenocarcinoma. in Oncology letters 2014 (PubMed)

  8. Human Polyclonal STAT3 Primary Antibody for IHC, ELISA - ABIN1531975 : Catlett-Falcone, Landowski, Oshiro, Turkson, Levitzki, Savino, Ciliberto, Moscinski, Fernández-Luna, Nuñez, Dalton, Jove: Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells. in Immunity 1999 (PubMed)

  9. Human Monoclonal STAT3 Primary Antibody for WB - ABIN1449165 : Yamashita, Miyagi, Carmany-Rampey, Shimizu, Fujii, Schier, Hirano: Stat3 Controls Cell Movements during Zebrafish Gastrulation. in Developmental cell 2002 (PubMed)

更多抗STAT3的相互作用对抗体

Mouse (Murine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. The results suggest that biochanin A activates RORgamma-dependent IL-17 (显示 IL17A 抗体) transcription through the enhancement of STAT3 phosphorylation and STAT3-mediated recruitment of NCOA1 (显示 NCOA1 抗体) to RORgamma.

  2. Loss of Sav1 (显示 SAV1 抗体) induced Stat3 activation and a senescence-associated secretory phenotype (SASP (显示 ASPRV1 抗体)) that coincided with the development of tubulointerstitial fibrosis.

  3. this study shows that STAT3-deficient Th9 cells have increased IL-9 (显示 IL9 抗体) production that is maintained for longer in culture than IL-9 (显示 IL9 抗体) in control cultures

  4. myeloid-specific Stat3 deletion causes defects in multiple aspects of the immune system

  5. LIF (显示 LIF 抗体)/STAT3 and MEK (显示 MDK 抗体)/ERK (显示 EPHB2 抗体) signaling in naive embryonic stem cell pluripotency, is reported.

  6. apoA-I (显示 APOA1 抗体)/ABCA1 (显示 ABCA1 抗体)-mediated cholesterol efflux without STAT3 activation can reduce proinflammatory cytokine expression in macrophages.

  7. IL-6 (显示 IL6 抗体) can directly induce the transition of HSCs toward myofibroblast-like cells. The effect is mediated by the activation of both MAPK (显示 MAPK1 抗体) and JAK (显示 JAK3 抗体)/STAT (显示 STAT1 抗体) signaling pathways. Elimination of either MAPK (显示 MAPK1 抗体) or JAK (显示 JAK3 抗体)/STAT (显示 STAT1 抗体) signaling pathways inhibits HSC (显示 FUT1 抗体) stimulation

  8. These findings also identify STAT3 as a therapeutic target against viral infection and highlight it as an essential pathway component for endogenous and therapeutic IFN-alpha (显示 IFNA 抗体) responsiveness.

  9. As a result of Tumour-associated macrophages (TAMs)-induced activation of the STAT3 pathway, murine 5T33MM cells are sensitized to AZD1480 treatment.

  10. Stat3-mediated regulation of expression of members of the calcium-activated chloride channel (显示 CLCA4 抗体) regulator (显示 CLNS1A 抗体) (CLCA) family of proteins during involution and mammary carcinogenesis.

Human Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Activated STAT3 upregulates the expression of GPx1 (显示 GPX1 抗体) and SOD2 (显示 SOD2 抗体), which reduce the intracellular ROS (显示 ROS1 抗体) levels in Burkitt lymphoma.

  2. Peritoneal membrane dysfunction in long-term peritoneal dialysis patients may result from IL-6 (显示 IL6 抗体) promotion of epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2 (显示 JAK2 抗体)/STAT3 signaling pathway.

  3. Data suggest that C-terminal truncated hepatitis B virus X protein (HBx-DeltaC1) enhances liver cancer stem cell (CSC) properties through Stat3/Nanog (显示 NANOG 抗体) cascade, and insight for the therapeutic intervention for hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC (显示 FAM126A 抗体)).

  4. High STAT3 expression is associated with Hepatocellular Carcinoma.

  5. Phosphorylation of STAT3 was decreased in NRDC (显示 NRD1 抗体)-depleted Huh-7 spheroids.

  6. Mutation inactivating STAT3 gene is associated with Breast Cancer Metastasis.

  7. The activation of NF-kappaB (显示 NFKB1 抗体) and STAT3 signalling-dependent pro-inflammatory cytokine expression.

  8. High STAT3 expression is associated with glioblastomas.

  9. High STAT3 expression is associated with nasopharyngeal cancer.

  10. In this review, we focus on the reciprocal regulation and roles of microRNAs and signal transducer and activator of transcription 3 in cancer, as well as describe current research progress on this relationship. A better understanding of this relationship may facilitate in the identification of targets for clinical therapeutics.

Cow (Bovine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. STAT3 might have potential effects on production traits in beef cattle populations and could be used for marker-assisted selection.

  2. Single-SNP analysis revealed a statistically significant association between SNP25402 in STAT3 and fertilization rate

  3. results show for the first time that interleukin-6 (显示 IL6 抗体) (IL), in the presence of its soluble receptor (显示 IFNAR1 抗体) (sIL (显示 STIL 抗体)-6R), induces activation of JAK1 (显示 JAK1 抗体), JAK2 (显示 JAK2 抗体), and STAT1 (显示 STAT1 抗体)/STAT3 proteins in bovine articular chondrocytes

  4. peroxynitrite causes increased expression of VEGF (显示 VEGFA 抗体) in vascular endothelial cells by a process that requires the activation of STAT3

  5. Simvastatin protects against the early signs of diabetic retinopathy by preventing NADPH oxidase (显示 NOX1 抗体)-mediated activation of STAT3.

Pig (Porcine) Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. this study shows that weaning caused severe inflammation associated with activation of the STAT3 pathway in the jejunum of piglets

  2. maternal dietary betaine supplementation during gestation inhibits hepatic cell proliferation in neonatal piglets, at least partly, through epigenetic regulation of hepatic CCND2 (显示 CCND2 抗体) and PSEN1 (显示 PSEN1 抗体) genes via a STAT3-dependent pathway

  3. Studied effect of recombinant porcine leukemia inhibitory factor (显示 LIF 抗体) on in vitro maturation of porcine oocytes; p-STAT3 markedly increased in both cumulus cells and oocytes cultured in pLIF (显示 FTH1 抗体)-supplemented media.

  4. Data suggest that IL-6 (interleukin 6 (显示 IL6 抗体)) prevents apoptosis in blastocysts (here, parthenotes) and enhances blastocyst/embryo viability through IL-6 (显示 IL6 抗体)/STAT3 signaling pathway (including up-regulation of STAT3 expression and phosphorylation).

  5. the distribution of tyrosine phosphorylated signal transducer and activator of transcription 3.

  6. Mitochondrial STAT3 activation has a causal role in mediating ischemic postconditioning cardioprotection through better mitochondrial function.

  7. STAT3 is likely altering mitochondrial function via transcriptional regulation or indirect signaling pathways

  8. Nuclear translocation of activated STAT3 and binding to STAT3 consensus DNA sequence were increased in the atrial fibrillation (AF) group.

Rabbit Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. This is the first report of the genetic polymorphisms of the JAK1 (显示 JAK1 抗体) and STAT3 genes and their associations with the incidence of non-specific digestive disorder in rabbits.

Guinea Pig Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Studied the role of T help 17 cells (Th17) and STAT3-VEGF pathway in pathogenesis of psoriasis.

  2. Activation of Stat3 signaling pathway may be involved in up-modulating the expression of MMP-2 (显示 MMP2 抗体) in guinea pig sclera fibroblasts, and not affect integrinbeta(1) expression.

Zebrafish Signal Transducer and Activator of Transcription 3 (Acute-Phase Response Factor) (STAT3) interaction partners

  1. Stat3 regulates cell proliferation and axis extension in part via upregulation of Cdc25a (显示 CDC25A 抗体) expression during oogenesis. Accordingly, restoring Cdc25a (显示 CDC25A 抗体) expression in stat3 mutants partially suppressed cell proliferation and gastrulation defects.

  2. PTPN9 (显示 PTPN9 抗体) plays an important role in erythropoiesis by disrupting an inhibitory complex of phosphorylated STAT3, GATA1 (显示 GATA1 抗体) and ZBP-89 (显示 ZNF148 抗体).

  3. Stat3-Efemp2a modulates the fibrillar matrix for cohesive movement of prechordal plate progenitors.

  4. Transgenic Stat3 inhibition in cardiomyocytes restricted injury-induced proliferation and regeneration, but did not reduce cardiogenesis during animal growth.

  5. This study demonistrated that Stat3 is necessary for the maximal number of Muller glia to proliferate during regeneration of the damaged zebrafish retina.

  6. The results of this study suggested that the stat3/socs3 (显示 SOCS3 抗体) pathway is a key response in all tissue regeneration in zebrafish.

  7. stat3, a known oncogene (显示 RAB1A 抗体) and a target of ss-catenin in multiple tissues, is upregulated in apc mutant zebrafish embryos.

  8. Cells undergoing convergence and extension movement may sense the gradient of signaling molecules, which are expressed in gastrula organizer by STAT3 and activate PCP (显示 PRCP 抗体) in neighboring cells during zebrafish gastrulation.

STAT3 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Three alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT3

  • signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3) 抗体
  • signal transduction and activation of transcription 3 (stat3) 抗体
  • signal transducer and activator of transcription 3 (acute-phase response factor) (stat3) 抗体
  • signal transducer and activator of transcription 3 (Stat3) 抗体
  • signal transducer and activator of transcription 3 (acute-phase response factor) (Stat3) 抗体
  • signal transducer and activator of transcription 3 (acute-phase response factor), gene 1 (stat3.1) 抗体
  • 1110034C02Rik 抗体
  • aprf 抗体
  • AW109958 抗体
  • hies 抗体
  • stat3 抗体
  • wu:fc15d02 抗体
  • wu:fl59g06 抗体
  • Xstat3 抗体
  • z-Stat3 抗体

Protein level used designations for STAT3

signal transducer and activator of transcription 3 (acute-phase response factor) , signal transducer and activator of transcription 3 , signal transduction and activation of transcription 3 , Signal transducer and activator of transcription 3 , signal transducer and activator of transcription 3-like , acute phase response factor , acute-phase response factor , DNA-binding protein APRF , Protein Stat3 , signal transducer and activator of transcription 3.1 , stat 3

GENE ID SPECIES
100011382 Monodelphis domestica
100171541 Pongo abelii
100380714 Salmo salar
100469938 Ailuropoda melanoleuca
100566559 Anolis carolinensis
100598877 Nomascus leucogenys
20848 Mus musculus
6774 Homo sapiens
25125 Rattus norvegicus
490967 Canis lupus familiaris
508541 Bos taurus
733648 Sus scrofa
420027 Gallus gallus
574128 Macaca mulatta
454682 Pan troglodytes
100348778 Oryctolagus cuniculus
100717084 Cavia porcellus
100294659 Ovis aries
779100 Xenopus laevis
30767 Danio rerio
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