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anti-STAT1 (STAT1) 抗体产品概述

Full name:
anti-Signal Transducer and Activator of Transcription 1, 91kDa 抗体 (STAT1)
在www.antibodies-online.cn可供604 Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) 抗体的36不同的供货商。 再加上,我们可以发STAT1 试剂盒 (46)STAT1 蛋白 (21)和数多这个蛋白质的别的产品。 总共715 STAT1产品已列进来了。
别名:
2010005J02Rik, AA408197, CANDF7, DD6G4-4, dZ182H3.3, H2RSP, IMUP, IMUP-1, IMUP-2, ISGF-3, si:by51f19.1, si:by134g18.2, si:dz73o4.2, si:dz182h3.3, si:dz199m19.1, STAT, STAT1, STAT4, STAT91, XStat1
列出全部抗体 基因 基因ID UniProt
STAT1 72275  
STAT1 25124  
STAT1 6772 P42224

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引用最多的anti-STAT1 抗体

  1. Human Polyclonal STAT1 Primary Antibody for EIA, IHC (p) - ABIN358231 : Garcin, Marq, Iseni, Martin, Kolakofsky: A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instability. in Journal of virology 2004 (PubMed)
    Show all 5 references for ABIN358231

  2. Human Polyclonal STAT1 Primary Antibody for EIA, IF - ABIN500815 : Leonard, OShea: Jaks and STATs: biological implications. in Annual review of immunology 1998 (PubMed)
    Show all 4 references for ABIN500815

  3. Cow (Bovine) Polyclonal STAT1 Primary Antibody for WB - ABIN2777895 : Battle, Lynch, Frank: Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis. in Cancer research 2006 (PubMed)
    Show all 2 references for ABIN2777895

  4. Human Monoclonal STAT1 Primary Antibody for IHC (p), IP - ABIN269146 : Kovarik, Boudny, Kocak, Lauerova, Fait, Vagundova: Malignant melanoma associates with deficient IFN-induced STAT 1 phosphorylation. in International journal of molecular medicine 2003 (PubMed)
    Show all 2 references for ABIN269146

  5. Human Polyclonal STAT1 Primary Antibody for IF, IHC - ABIN1533008 : Durbin, Hackenmiller, Simon, Levy: Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease. in Cell 1996 (PubMed)
    Show all 2 references for ABIN1533008

  6. Human Polyclonal STAT1 Primary Antibody for ELISA, WB - ABIN1533729 : Hillier, Graves, Fulton, Fulton, Pepin, Minx, Wagner-McPherson, Layman, Wylie, Sekhon, Becker, Fewell, Delehaunty, Miner, Nash, Kremitzki, Oddy, Du, Sun, Bradshaw-Cordum, Ali, Carter, Cordes, Harris et al.: Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ... in Nature 2005 (PubMed)

更多抗STAT1的相互作用对抗体

Mouse (Murine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. IFN-I can mediate ISG expression inmixed glial cell cultures (MGCs) via ISGF3 (显示 IRF9 抗体)-independent signaling pathways but with reduced efficiency, with delayed and prolonged kinetics, and is more dependent on STAT1 and STAT2 (显示 STAT2 抗体) than IRF9 (显示 IRF9 抗体); and 2) signaling pathways not involving STAT1, STAT2 (显示 STAT2 抗体), or IRF9 (显示 IRF9 抗体) play a minor role only in mediating IFN-alpha (显示 IFNA 抗体)-stimulated genes expression in MGCs.

  2. These results demonstrate a novel mechanism by which STAT1 negatively regulates ULK1 (显示 ULK1 抗体) expression and autophagy.

  3. a novel negative feedback loop mediated by STAT3 (显示 STAT3 抗体)-SOCS3 (显示 SOCS3 抗体), which is tightly controlled by SENP1 (显示 SENP1 抗体) via de-SUMOylation of protein tyrosine phosphatase 1B (PTP1B (显示 PTPN1 抗体)), in IFN-gamma (显示 IFNG 抗体) signaling, is reported.

  4. In a mouse model of spontaneous osteopenia caused by hyperactivation of STAT1/3 signaling downstream of gp130 (gp130 (显示 LRPPRC 抗体)(Y757F/Y757F)), STAT1 deletion rescued the osteopenic phenotype, indicating a beneficial effect of promoting STAT3 (显示 STAT3 抗体) signaling over STAT1 downstream of gp130 (显示 LRPPRC 抗体) in this low bone mass condition, and this may have therapeutic value.

  5. this study shows that STAT-1 and STAT-3 (显示 STAT3 抗体) interplay to regulate indoleamine 2,3-dioxygenase activity and immunosuppression in response to of IL-27 (显示 IL27 抗体) in neonatal macrophages

  6. this study shows that binding motifs for the transcription factors STAT1 and IRF1 (显示 IRF1 抗体) are associated with robust and IL-4 (显示 IL4 抗体)-resistant responses to IFN-gamma (显示 IFNG 抗体) in macrophages

  7. Study showed that suppression of STAT3 (显示 STAT3 抗体), STAT5 (显示 STAT5A 抗体), and STAT6 (显示 STAT6 抗体) and overexpression of the proapoptotic factor STAT1, which provides p53 (显示 TP53 抗体)-mediated apoptosis, are the causes for increasing the number of apoptotic neurons in physiological aging. HER-2 (显示 ERBB2 抗体) tyrosine kinase receptor (显示 KDR 抗体) overexpression promotes neuronal survival through activation of STAT-signaling pathway with simultaneous suppression of the proapoptotic factor STAT1

  8. STAT signaling plays a central role during retinal degeneration in the rd10 (显示 PDE6B 抗体) mouse model.

  9. Donor interleukin-22 (显示 IL22 抗体) and host type I interferon (显示 IFNA 抗体) signaling pathway participate in intestinal graft-versus-host disease via STAT1 activation and CXCL10 (显示 CXCL10 抗体).

  10. OGG1 (显示 OGG1 抗体) acts as a STAT1 coactivator and has transcriptional activity in the presence of endotoxin

Human Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. the dual regulation of STAT1 by IKKalpha (显示 CHUK 抗体) in antiviral signaling suggests a role for IKKalpha (显示 CHUK 抗体) in the fine-tuning of antiviral signaling in response to non-self RNA.

  2. This study demonstrated the first coiled-coil domain mutation of STAT1 as a genetic cause of autosomal-dominant Mendelian susceptibility to mycobacterial diseases

  3. STAT1 suppression by S100A6 (显示 S100A6 抗体) may represent a promising therapeutic target to facilitate reendothelialization in damaged vessels.

  4. Our data demonstrate an important connection between mRNA translation and KRAS tumorigenesis under the control of STAT1, which can determine the susceptibility of KRAS tumors to pharmacologic inhibition of mRNA translation initiation.

  5. study demonstrated that miR (显示 MLXIP 抗体)-9 could inhibit activation of the NLRP3 (显示 NLRP3 抗体) inflammasome and attenuate atherosclerosis-related inflammation, likely through the JAK1 (显示 JAK1 抗体)/STAT1 signaling pathway. Therefore, miR (显示 MLXIP 抗体)-9 may serve as a potential therapeutic target for atherosclerosis.

  6. the deubiquitinase USP2a translocates into the nucleus and binds to pY701-STAT1, and inhibits K48-linked ubiquitination and degradation of pY701-STAT1

  7. Demonstrate STAT1-dependent transcriptional activation of TLR8 (显示 TLR8 抗体) with estrogen stimulation.

  8. STAT1 binding sites were identified on the putative miR-7 (显示 LILRB1 抗体) promoter and stimulation of fibroblasts with the inflammatory cytokine, interferon-gamma (IFN-gamma (显示 IFNG 抗体)), significantly increased miR-7 (显示 LILRB1 抗体) transcriptional activity and resulted in upregulated miR-7 (显示 LILRB1 抗体) and loss of EGFR (显示 EGFR 抗体).

  9. These results demonstrate a novel mechanism by which STAT1 negatively regulates ULK1 (显示 ULK1 抗体) expression and autophagy.

  10. In insulitic islets from living patients with recent-onset T1D, most of the overexpressed ISGs, including GBP1 (显示 GBP1 抗体), TLR3 (显示 TLR3 抗体), OAS1 (显示 OAS1 抗体), EIF2AK2 (显示 EIF2AK2 抗体), HLA-E (显示 HLAE 抗体), IFI6 (显示 IFI6 抗体), and STAT1, showed higher expression in the islet core compared with the peri (显示 PLIN1 抗体)-islet area containing the surrounding immune cells.

Pig (Porcine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. Collectively, these data show that porcine epidemic diarrhea virus is capable of subverting the type I interferon (显示 IFNA 抗体) response by inducing STAT1 degradation.

  2. this study shows that weaning caused severe inflammation associated with the suppression of STAT1 in the jejunum of piglets

  3. Data indicate that transmissible gastroenteritis virus (TGEV) infection activates the janus kinase signal transducer and activator of the transcription 1 (JAK (显示 JAK3 抗体)-STAT1) signaling pathway.

  4. Taken together, results of these experiments describe for the first time a novel mechanism by which foot-and-mouth disease virus evolves to inhibit IFN signaling via blocking STAT1/STAT2 (显示 STAT2 抗体) nuclear translocation.

  5. Nsp1beta inhibits interferon-activated (显示 MNDA 抗体) STAT1/STAT2 (显示 STAT2 抗体) signal transduction by inducing karyopherin-alpha1 degradation.

  6. STAT1 is involved in mediating the action of ghrelin (显示 GHRL 抗体) on ovarian cell functions.

  7. the majority of the STAT1/STAT2 (显示 STAT2 抗体)/IRF9 (显示 IRF9 抗体) (IFN regulatory factor 9) heterotrimers remained in the cytoplasm of PRRSV-infected cells, which indicates that the nuclear translocation of the heterotrimers was blocked

  8. Cell-type-specific expression of STAT1 highlight the complex interplay between endometrium and conceptus for pregnancy recognition and implantation.

  9. Nitric oxide-dependent increase in caspase-8 (显示 CASP8 抗体) mRNA levels is associated with phosphorylation of STAT-1 at Ser (显示 SIGLEC1 抗体)-727 and STAT1 binding to the caspase-8 (显示 CASP8 抗体) promoter in cultured lung endothelial cells.

  10. Activated STAT1 may be associated with or perhaps contribute to the structural and inflammatory changes in pacing-induced sustained atrial fibrillation.

Cow (Bovine) Signal Transducer and Activator of Transcription 1, 91kDa (STAT1) interaction partners

  1. Report interferon-tau dependent STAT1 regulation of SOCS (显示 CISH 抗体) genes in bovine endometrium during estrus cycle and embryo implantation.

  2. the interaction between STAT1 SNP and SNP19069 was highly significant for survival rate

  3. results show for the first time that interleukin-6 (显示 IL6 抗体) (IL), in the presence of its soluble receptor (显示 IFNAR1 抗体) (sIL (显示 STIL 抗体)-6R), induces activation of JAK1 (显示 JAK1 抗体), JAK2 (显示 JAK2 抗体), and STAT1/STAT3 (显示 STAT3 抗体) proteins in bovine articular chondrocytes

  4. Results from this study are consistent with previous studies on the role of STAT1 in regulating the transcription of genes involved in milk protein (显示 CSN2 抗体) synthesis and fat metabolism.

  5. Prolonged treatment with IFN-alpha (12-48 h) resulted in increased expression of STAT1 and, to a lesser extent, STAT2 (显示 STAT2 抗体).

STAT1 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described.

Alternative names and synonyms associated with STAT1

  • signal transducer and activator of transcription 1, 91kDa (STAT1) 抗体
  • RIKEN cDNA 2200002D01 gene (2200002D01Rik) 抗体
  • signal transducer and activator of transcription 1 (Stat1) 抗体
  • signal transducer and activator of transcription 1, 91kDa (stat1) 抗体
  • signal transducer and activator of transcription 4 (stat4) 抗体
  • 2010005J02Rik 抗体
  • AA408197 抗体
  • CANDF7 抗体
  • DD6G4-4 抗体
  • dZ182H3.3 抗体
  • H2RSP 抗体
  • IMUP 抗体
  • IMUP-1 抗体
  • IMUP-2 抗体
  • ISGF-3 抗体
  • si:by51f19.1 抗体
  • si:by134g18.2 抗体
  • si:dz73o4.2 抗体
  • si:dz182h3.3 抗体
  • si:dz199m19.1 抗体
  • STAT 抗体
  • STAT1 抗体
  • STAT4 抗体
  • STAT91 抗体
  • XStat1 抗体

Protein level used designations for STAT1

signal transducer and activator of transcription 1-alpha/beta , HAI-2 related small protein , signal transducer and activator of transcription-1 , transcription factor ISGF-3 components p91/p84 , signal transducer and activator of transcription 4 , signal transducer and activator of transcription 1 , transcription factor ISGF-3 , activator of transcription , signal transduction

GENE ID SPECIES
100307049 Ovis aries
72275 Mus musculus
20846 Mus musculus
25124 Rattus norvegicus
6772 Homo sapiens
424044 Gallus gallus
488449 Canis lupus familiaris
396655 Sus scrofa
510814 Bos taurus
398324 Xenopus laevis
100343893 Oryctolagus cuniculus
368519 Danio rerio
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