anti-SRC (SRC) 抗体产品概述

Full name:
anti-V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) 抗体 (SRC)
在www.antibodies-online.cn可供450 V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) 抗体的30不同的供货商。 再加上,我们可以发SRC 蛋白 (22)SRC 试剂盒 (20)和数多这个蛋白质的别的产品。 总共518 SRC产品已列进来了。
别名:
ASV, AW259666, c-Src, C-src1, CG7524, D-src, D-Src64B, Dmel\CG7524, DmHD-358, Dm SRC1, dsrc, Dsrc64, Dsrc64B, HD-358, MRE5, p60-Src, PP60C-SCR, pp60c-src, SDR, src, SRC1, src64, SRC 64B, src64b

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引用最多的anti-SRC 抗体

  1. Human Polyclonal SRC Primary Antibody for WB - ABIN1881832 : Kieslinger, Hiechinger, Dobreva, Consalez, Grosschedl: Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner. in Cell stem cell 2010 (PubMed)
    Show all 5 references for 1881832

  2. Human Polyclonal SRC Primary Antibody for FACS, IF - ABIN1881833 : Pradhan, Alrehani, Patel, Khatlani, Vijayan: Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin αIIbβ3 to fibrinogen. in The Journal of biological chemistry 2010 (PubMed)
    Show all 5 references for 1881833

  3. Human Monoclonal SRC Primary Antibody for IF, WB - ABIN387822 : Chen, Li, Zhang, Yi, Chen, Wang, Zhang: Src-stimulated IRTKS phosphorylation enhances cell migration. in FEBS letters 2011 (PubMed)
    Show all 2 references for 387822

  4. Human Polyclonal SRC Primary Antibody for IHC, ELISA - ABIN1533006 : Xu, Harrison, Eck: Three-dimensional structure of the tyrosine kinase c-Src. in Nature 1997 (PubMed)
    Show all 2 references for 1533006

  5. Human Polyclonal SRC Primary Antibody for IHC, ELISA - ABIN1531972 : Benes, Wu, Elia, Dharia, Cantley, Soltoff: The C2 domain of PKCdelta is a phosphotyrosine binding domain. in Cell 2005 (PubMed)
    Show all 2 references for 1531972

  6. Human Polyclonal SRC Primary Antibody for IHC, ELISA - ABIN1532080 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

  7. Cow (Bovine) Polyclonal SRC Primary Antibody for WB - ABIN2779668 : Pechkovsky, Scaffidi, Hackett, Ballard, Shaheen, Thompson, Thannickal, Knight: Transforming growth factor beta1 induces alphavbeta3 integrin expression in human lung fibroblasts via a beta3 integrin-, c-Src-, and p38 MAPK-dependent pathway. in The Journal of biological chemistry 2008 (PubMed)

更多抗SRC的相互作用对抗体

Mouse (Murine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. PTPN2 (显示 PTPN2 抗体) is a positive regulator of lipopolysaccharide-induced inflammatory response by enhancing the activity of Src through targeting the inhibitory phosphor-tyrosine527 of Src.

  2. demonstrated that both IL-10 (显示 IL10 抗体) and TGF-beta (显示 TGFB1 抗体) upregulated TIM-3 (显示 HAVCR2 抗体) surface expression on dendritic cells via a common signaling pathway that involved sequential activation of c-Src and Bruton's tyrosine kinase (显示 BTK 抗体)

  3. Results suggest that interleukin-6 (IL-6 (显示 IL6 抗体)) increases VEGF-C (显示 VEGFC 抗体) induction and lymphangiogenesis may involve, at least in part, Src-FAK (显示 PTK2 抗体)-STAT3 (显示 STAT3 抗体) cascade in lymphatic endothelial cells (LECs).

  4. Transcriptional signature induced by a metastasis-promoting c-Src mutant in a human breast cell line has been reported.

  5. Data show that the essential oil (EO) decreased focal adhesion and invadopodia formation which was accompanied by a drastic downregulation of focal adhesion kinase (FAK) and proto-oncogene protein Src.

  6. miR (显示 MLXIP 抗体)-222-3p serves as an inhibitor of osteoclastogenesis and c-Src mediates its inhibition of cathepsin K (显示 CTSK 抗体) and TRAP.

  7. results suggest that LPS (显示 TLR4 抗体)-stimulated macrophage mediators attenuate both FAK (显示 PTK2 抗体) and Src activations in osteoblast, suggesting a novel role for TNFalpha (显示 TNF 抗体) on osteoblast performance

  8. Src has a role in priming Pyk2 (显示 PTK2B 抗体) (but not FAK (显示 PTK2 抗体)) phosphorylation and subsequent activation downstream of integrins

  9. Heritable pulmonary arterial hypertension (PAH) results from increased SRC activation, cellular contraction, and vascular resistance, but antagonism of HTR2B prevents SRC phosphorylation and development of PAH.

  10. Periodic axial motility of epithelial basal cell projections is controlled by c-Src.

Fruit Fly (Drosophila melanogaster) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. Src64 controls actin dynamics to mediate proper ring canal formation during incomplete cytokinesis during germline cyst development in vivo

  2. that Brat represses the translation of src64B, an upstream regulator of a conserved Rho-dependent pathway previously shown to promote axon retraction

  3. Results show that Src42a and Src64b are required for the normal division capacity of Drosophila intestinal progenitor cells, and that these genes as well as Ack cause progenitor overproliferation in the intestine via core cell cycle activation.

  4. a novel essential role for Src in intestinal stem/progenitor cell proliferation and tumourigenesis initiation in vivo.

  5. Data show that the actin-Capping Protein (显示 TMOD4 抗体) (CP) alphabeta heterodimer, which regulates actin (显示 ACTB 抗体) filament (F-actin (显示 ACTB 抗体)) polymerization, limits Src-induced apoptosis or tissue overgrowth by restricting JNK (显示 MAPK8 抗体) activation.

  6. Dumbfounded/Neph1 (显示 NEPH1 抗体), a key diaphragm constituent, is a target of the Src kinase (显示 CSK 抗体) Src64B. Loss of Src64B activity leads to a reduction in the number of diaphragms, and this effect is in part mediated by loss of Dumbfounded/Neph1 (显示 NEPH1 抗体) tyrosine phosphorylation.

  7. Homodimerization of the Wnt receptor DERAILED recruits the Src family kinase SRC64B in the developing embryonic central nervous system.

  8. E4orf4 has a role in inducing PP2A (显示 PPP2R2B 抗体)- and Src-dependent cell death while inhibiting classic apoptosis pathways in Drosophila melanogaster

  9. Mutations in a Drosophila src gene, src64, that alter the three HRD amino acids, were identified.

  10. Src64B overexpression induced the formation of specialized haemocytes (lamellocytes), but had no effect on circulating plasmatocyte concentration. Src64B overexpression induced F-actin (显示 ACTB 抗体) formation and Jun kinase (显示 MAPK9 抗体) activation in plasmatocytes.

Human V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. Results indicate Src homology 3 (SH3) domain-binding glutamic acid-rich-like protein (SH3BGRL) in driving tumor metastasis through c-Src activation, and suggests that hSH3BGRL mutation status could be relevant to cancer diagnosis and therapy.

  2. overexpression of syndecan-1 confers to B-LCs an increased capacity to migrate in response to Tat, owing to a switch from a CXCR4/G-protein/Rac to a syndecan-1/alphavbeta3/pp60src/pp125FAK signal transduction pathway that depends on the formation of a complex in which syndecan-1 interacts with Tat via its HS-chains, with alphavbeta3 via its core protein ectodomain and with pp60src via its intracellular tail

  3. the direct binding of ERalpha (显示 ESR1 抗体)-36 to ERK2 (显示 MAPK1 抗体) prevents its dephosphorylation by MKP3 (显示 DUSP6 抗体) and enhances the downstream signaling. These findings improve our understanding of the regulation of non-genomic estrogen signaling and open new avenues for personalized therapeutic approaches targeting Src or MEK (显示 MAP2K1 抗体) in ERalpha (显示 ESR1 抗体)-36-positive patients.

  4. Csk (显示 CSK 抗体) induced phosphorylation of Src at tyrosine 530.

  5. regulation of Src activation and translocation

  6. SDCBP (显示 SDCBP 抗体) might be an important marker for identifying Triple negative breast cancer cases that are suitable for dasatinib therapy.

  7. Restoring miR (显示 MLXIP 抗体)-34a expression resulted in down-regulation of c-SRC and phosphorylated (Tyr416) c-SRC protein in K-562 cells, which consequently triggered suppression of the RAF (显示 RAF1 抗体)/MEK (显示 MAP2K1 抗体)/ERK (显示 EPHB2 抗体) signaling pathway to decrease cell proliferation.

  8. This study suggests PRL-3 and SFKs are key mediators of the IL6 (显示 IL6 抗体)-driven signaling events.

  9. the N-terminus of survivin (显示 BIRC5 抗体) is a mitochondrial-targeting sequence that regulates Src.

  10. These results suggest that the activation of endogenous levels of SFK renders the endothelial barrier more susceptible to low, physiologic doses of TNF-alpha (显示 TNF 抗体) through activation of p38 (显示 CRK 抗体) which leads to a loss of endothelial tight junctions.

Cow (Bovine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. RhoA (显示 RHOA 抗体) and membrane fluidity mediates the spatially polarized Src/FAK (显示 PTK2 抗体) activation in response to shear stress.

  2. AngII activates PKD via a mechanism involving Src family kinases and PKC, to underlie increased aldosterone production.

  3. The Src gene possibly contributed to conducting association analysis and can be recognized as genetic marker in milk production traits and other performance for animal breeding and genetics.

  4. src has a role in activation of 5'-AMP (显示 TMPRSS5 抗体)-activated kinase during hypoxia-reoxygenation of bovine aortic endothelial cells

  5. results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network

  6. These results suggest that TGF-beta1 (显示 TGFB1 抗体)-induced monolayer permeability involves focal adhesion and cytoskeletal rearrangement through both FAK (显示 PTK2 抗体)/Src-dependent and -independent pathways.

Pig (Porcine) V-Src Sarcoma (Schmidt-Ruppin A-2) Viral Oncogene Homolog (Avian) (SRC) interaction partners

  1. The findings are consistent with previous studies that indicate a link between Na,K-ATPase (显示 ATP1A1 抗体) activity and SFK signaling.

  2. Src kinase (显示 CSK 抗体) mediates hypoxia-induced caspase-1 (显示 CASP1 抗体) activation in the cerebral cortex of newborn piglets

  3. Expression of mutant alpha1 Na/K-ATPase (显示 ATP1A1 抗体) defective in conformational transition attenuates Src-mediated signal transduction

  4. 20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.

SRC 抗原简介

Antigen Summary

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Alternative names and synonyms associated with SRC

  • v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC) 抗体
  • proto-oncogene tyrosine-protein kinase src (AaeL_AAEL002471) 抗体
  • proto-oncogene tyrosine-protein kinase src (CpipJ_CPIJ010659) 抗体
  • Rous sarcoma oncogene (Src) 抗体
  • Src oncogene at 64B (Src64B) 抗体
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (SRC) 抗体
  • v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Src) 抗体
  • v-src sarcoma viral oncogene (SRC) 抗体
  • ASV 抗体
  • AW259666 抗体
  • c-Src 抗体
  • C-src1 抗体
  • CG7524 抗体
  • D-src 抗体
  • D-Src64B 抗体
  • Dmel\CG7524 抗体
  • DmHD-358 抗体
  • Dm SRC1 抗体
  • dsrc 抗体
  • Dsrc64 抗体
  • Dsrc64B 抗体
  • HD-358 抗体
  • MRE5 抗体
  • p60-Src 抗体
  • PP60C-SCR 抗体
  • pp60c-src 抗体
  • SDR 抗体
  • src 抗体
  • SRC1 抗体
  • src64 抗体
  • SRC 64B 抗体
  • src64b 抗体

Protein level used designations for SRC

proto-oncogene tyrosine-protein kinase SRC , proto-oncogene tyrosine-protein kinase src , neuronal proto-oncogene tyrosine-protein kinase Src , p60-Src , proto-oncogene c-Src , CG7524-PB , CG7524-PC , CG7524-PD , CG7524-PE , CG7524-PF , CG7524-PG , CG7524-PH , CG7524-PI , CG7524-PJ , Src proto oncogene sequence , Src64B-PB , Src64B-PC , Src64B-PD , Src64B-PE , Src64B-PF , Src64B-PG , Src64B-PH , Src64B-PI , Src64B-PJ , mRNA-like ncRNA in embryogenesis 5 , proto-oncogene tyrosine-protein kinase Src , protooncogene SRC, Rous sarcoma , tyrosine kinase pp60c-src , tyrosine-protein kinase SRC-1 , Rous sarcoma oncogene , c-Src , pp60c-src , tyrosine protein kinase c-src , tyrosine protein kinase pp60-c-src , v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog , src oncogene , v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog , non-tyrosine protein kinase

GENE ID SPECIES
458229 Pan troglodytes
5574802 Aedes aegypti
6043642 Culex quinquefasciatus
20779 Mus musculus
48973 Drosophila melanogaster
6714 Homo sapiens
83805 Rattus norvegicus
485864 Canis lupus familiaris
535742 Bos taurus
100154503 Sus scrofa
396442 Gallus gallus
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