anti-PIAS3 (PIAS3) 抗体产品概述

Full name:
anti-Protein Inhibitor of Activated STAT, 3 抗体 (PIAS3)
在www.antibodies-online.cn可供66 Protein Inhibitor of Activated STAT, 3 (PIAS3) 抗体的24不同的供货商。 再加上,我们可以发PIAS3 试剂盒 (14)PIAS3 蛋白 (6)和数多这个蛋白质的别的产品。 总共95 PIAS3产品已列进来了。
PIAS3, Pias3l, ZMIZ5

最受欢迎的抗anti-PIAS3 (PIAS3) 抗体


抗Mouse (Murine) PIAS3 抗体:

抗Human PIAS3 抗体:

抗Rat (Rattus) PIAS3 抗体:

所有可销售的anti-PIAS3 抗体


引用最多的anti-PIAS3 抗体

  1. Human Polyclonal PIAS3 Primary Antibody for IHC (p), WB - ABIN1882115 : Nojiri, Joh, Miura, Sakata, Nomura, Nakao, Sobue, Ohara, Asai, Ito: ATBF1 enhances the suppression of STAT3 signaling by interaction with PIAS3. in Biochemical and biophysical research communications 2004 (PubMed)
    Show all 7 references for 1882115

  2. Human Polyclonal PIAS3 Primary Antibody for IHC (p), WB - ABIN1882116 : Long, Wang, Matsuura, He, Liu: Activation of Smad transcriptional activity by protein inhibitor of activated STAT3 (PIAS3). in Proceedings of the National Academy of Sciences of the United States of America 2004 (PubMed)
    Show all 7 references for 1882116

  3. Cow (Bovine) Polyclonal PIAS3 Primary Antibody for IHC, WB - ABIN2777574 : Jang, Yoon, Shin, Kim, Lee: PIAS3 suppresses NF-kappaB-mediated transcription by interacting with the p65/RelA subunit. in The Journal of biological chemistry 2004 (PubMed)

  4. Cow (Bovine) Polyclonal PIAS3 Primary Antibody for WB - ABIN2777575 : Roukens, Alloul-Ramdhani, Vertegaal, Anvarian, Balog, Deelder, Hensbergen, Baker: Identification of a new site of sumoylation on Tel (ETV6) uncovers a PIAS-dependent mode of regulating Tel function. in Molecular and cellular biology 2008 (PubMed)


Rhesus Monkey Protein Inhibitor of Activated STAT, 3 (PIAS3) interaction partners

  1. Suppressed Th17 levels correlated with upregulated expression of negative regulatory genes, PIAS3, SHP2, and SOCS3 in CD4 T cells during acute SIV infection.

Mouse (Murine) Protein Inhibitor of Activated STAT, 3 (PIAS3) interaction partners

  1. Data indicate that PIAS3 (protein inhibitor of activated STAT3) interaction modulates EKLF (erythroid Kruppel-like factor (显示 KLF1 抗体)) activity in a promoter-dependent and SUMO-independent manner.

  2. PIAS3 suppresses acute graft-versus-host disease by modulating effector T and B cell subsets through inhibition of STAT3 (显示 STAT3 抗体) activation.

  3. These data indicate that tachypacing decreased ATBF1 (显示 ZFHX3 抗体), leading to enhanced STAT3 (显示 STAT3 抗体) DNA-binding activity due to the reduced formation of a binary complex of ATBF1 (显示 ZFHX3 抗体) and PIAS3.

  4. MRL/lpr (显示 FAS 抗体) mice have significantly increased expressions of STAT3 (显示 STAT3 抗体) mRNA and protein and decreased expression of mRNA PIAS3 in the kidneys compared with BALB/C mice.

  5. L97A, R99N and R99Q mutations of the PINIT domain (PIAS3(85-272) ) were found to abrogate binding to STAT3 (显示 STAT3 抗体), suggesting that these residues were part of a potential binding surface.

  6. Our results indicate that Pias3-dependent SUMOylation of photoreceptor-specific transcription factors is a common mechanism that controls both rod and cone photoreceptor subtype specification, regulating distinct molecular targets in the two cell types

  7. there is an interaction between Zimp7 (显示 ZMIZ2 抗体) and PIAS (显示 PIAS1 抗体) proteins with higher preference for PIAS3, in androgen receptor (显示 AR 抗体)-mediated transcription

  8. results indicate a potential role of PIAS3 as transcriptional modulator of TIF2 (显示 NCOA2 抗体)-mediated signalling

  9. role in inducing SUMO-1 (显示 SUMO1 抗体) modification and transcriptional repression of IRF-1 (显示 IRF1 抗体)

  10. identified a novel conserved domain of 180 residues in PIAS (显示 PIAS1 抗体) proteins and showed that its 'PINIT' motif as well as other conserved motifs (in the SAP (显示 APCS 抗体) box and in the RING domain) are independently involved in nuclear retention of PIAS3L

Human Protein Inhibitor of Activated STAT, 3 (PIAS3) interaction partners

  1. SHP2 (显示 PTPN11 抗体), SOCS3 (显示 SOCS3 抗体) and PIAS3 levels are reduced in medulloblastomas in vivo and in vitro, of which PIAS3 downregulation is more reversely correlated with STAT3 (显示 STAT3 抗体) activation. In resveratrol-suppressed medulloblastoma cells with STAT3 (显示 STAT3 抗体) downregulation and decreased incidence of STAT3 (显示 STAT3 抗体) nuclear translocation, PIAS3 is upregulated, the SHP2 (显示 PTPN11 抗体) level remains unchanged and SOCS3 (显示 SOCS3 抗体) is downregulated.

  2. The results revealed that although the expression levels of SOCS1 (显示 SOCS1 抗体), SOCS3 (显示 SOCS3 抗体) and, in particular, pSHP2, tend to decrease in the four types of astrocytomas, PIAS3 downregulation is more negatively correlated with STAT3 (显示 STAT3 抗体) activation in the stepwise progress of astrocytomas and would indicate an unfavorable outcome.

  3. 3-Formylchromone inhibits proliferation and induces apoptosis of multiple myeloma cells by abrogating STAT3 (显示 STAT3 抗体) signaling through the induction of PIAS3.

  4. PIAS3 may serve as a biomarker for predicting hormone therapy stratification, although it is limited to those breast cancer patients receiving hormone therapy.

  5. Taken together, these results suggest that PIAS3 functions as a positive regulator of HIF-1alpha (显示 HIF1A 抗体)-mediated transcription by increasing its protein stability.

  6. PIAS3 suppression may be protective against joint destruction in rheumatoid arthritis by regulating synoviocyte migration, invasion, and activation.

  7. PIAS3 primes ATR for checkpoint activation.

  8. PIAS3 expression in squamous cell lung cancer is low and predicts overall survival

  9. Adenovirus E4-ORF3 (显示 ASZ1 抗体) targets PIAS3 and together with E1B (显示 BCKDHB 抗体)-55K remodels SUMO2/SUMO3 Interactions in the nucleus and at virus genome replication domains.

  10. Statistically significant positive correlation has been found between STAT5B (显示 STAT5B 抗体) and COX-2 (显示 COX2 抗体), and significant negative correlation between STAT5B (显示 STAT5B 抗体) and PIAS3.

PIAS3 抗原简介

Antigen Summary

This gene encodes a member of the PIAS

Alternative names and synonyms associated with PIAS3

  • protein inhibitor of activated STAT, 3 (PIAS3) 抗体
  • protein inhibitor of activated STAT, 3 (pias3) 抗体
  • protein inhibitor of activated STAT 3 (Pias3) 抗体
  • protein inhibitor of activated STAT, 3 (Pias3) 抗体
  • protein inhibitor of activated STAT, 3 (LOC100341019) 抗体
  • PIAS3 抗体
  • Pias3l 抗体
  • ZMIZ5 抗体

Protein level used designations for PIAS3

protein inhibitor of activated STAT, 3 , E3 SUMO-protein ligase PIAS3-like , e3 SUMO-protein ligase PIAS3-like , E3 SUMO-protein ligase PIAS3 , protein inhibitor of activated STAT protein 3 , zinc finger, MIZ-type containing 5 , KChAP , potassium channel regulatory protein KChAP , potassium channel-associated protein

457223 Pan troglodytes
706775 Macaca mulatta
100144644 Xenopus (Silurana) tropicalis
100401461 Callithrix jacchus
100461795 Pongo abelii
100483204 Ailuropoda melanoleuca
229615 Mus musculus
10401 Homo sapiens
83614 Rattus norvegicus
444507 Xenopus laevis
483160 Canis lupus familiaris
535312 Bos taurus
100511878 Sus scrofa
100341019 Oryctolagus cuniculus
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