JAK2 (JAK2) ELISA试剂盒产品概述

Full name:
Janus Kinase 2 ELISA试剂盒 (JAK2)
在www.antibodies-online.cn可供26 Janus Kinase 2 (JAK2) ELISA试剂盒的11不同的供货商。 再加上,我们可以发JAK2 抗体 (264)JAK2 蛋白 (21)和数多这个蛋白质的别的产品。 总共324 JAK2产品已列进来了。
别名:
AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

适于 JAK2 相互作用对的更多 ELISA 试剂盒

Zebrafish Janus Kinase 2 (JAK2) interaction partners

  1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma (显示 IFNG ELISA试剂盒) signal.

Human Janus Kinase 2 (JAK2) interaction partners

  1. JAK2 was overexpressed in Epstein Barr virus-associated gastric adenocarcinoma.

  2. As marrow histology in this murine model of myeloproliferation reveals a preferentially perivascular localization of JAK2(V617F)-mutant megakaryocytes and an increased marrow sinusoid vascular density

  3. mutated FLT3 (显示 FLT3 ELISA试剂盒)-ITD and JAK2 augment reactive oxygen species production and homologous recombination, shifting the cellular milieu toward illegitimate recombination events.

  4. Germ line JAK2 mutations E846D and R1063H are associated with hereditary erythrocytosis with megakaryocytic atypia.

  5. Data suggest that ruxolitinib treatment for up to 4 years provides progressive reductions in Janus kinase 2 (JAK2) p.V617F allele burden in patients with polycythemia vera (显示 IGF2BP3 ELISA试剂盒) (PV).

  6. Mice expressing the human JAK2-N542-E543del (Ex12) showed a strong increase in red blood cell parameters but normal neutrophil and platelet counts, and reduced overall survival. Erythropoiesis was increased in the bone marrow and spleen, with normal megakaryopoiesis and absence of myelofibrosis in histopathology.

  7. data indicate that a low positivity of JAK2 V617F can be seen in MPN (显示 PRSS27 ELISA试剂盒) as well as reactive conditions

  8. These data indicate that the same germ line variants endow individuals with a predisposition not only to myeloproliferative neoplasms, but also to JAK2 V617F clonal hematopoiesis.

  9. Data suggest that myeloproliferative neoplasms (MPN (显示 PRSS27 ELISA试剂盒)) patients with Janus kinase 2 (JAK2) V617F allele burden higher than 75% have to be considered as high risk patients, being prone to develop thrombo-hemorrhagic complications during the disease course.

  10. While the overall architecture and interdomain orientations are preserved between Jak2 and Tyk2 (显示 TYK2 ELISA试剂盒), we identify residues in the putative receptor-binding groove that differ between the two and may contribute to the specificity of receptor recognition

Mouse (Murine) Janus Kinase 2 (JAK2) interaction partners

  1. Study shows that Jak2 with V617F mutation induces murine model for myeloproliferative neoplasm.

  2. results suggest that loss of Ezh2 (显示 EZH2 ELISA试剂盒) cooperates with Jak2V617F in the development of myelofibrosis in Jak2V617F

  3. JAK2-V617F-expressing mice treated with an Ezh2 (显示 EZH2 ELISA试剂盒) inhibitor showed higher platelet counts than vehicle controls. Our data support the proposed tumor suppressor function of EZH2 (显示 EZH2 ELISA试剂盒)

  4. findings demonstrate that clinically relevant doses of the JAK1 (显示 JAK1 ELISA试剂盒)/2 inhibitor ruxolitinib suppresses the harmful consequences of macrophage overactivation characterizing Hemophagocytic lymphohistiocytosis in 2 murine models.

  5. JAK2 has a role in hepatocarcinogenesis through regulating critical inflammatory pathways

  6. Data show that CUZD1 (显示 CUZD1 ELISA试剂盒) interacts with a complex containing JAK1 (显示 JAK1 ELISA试剂盒)/JAK2 and STAT5 (显示 STAT5A ELISA试剂盒), downstream transducers of prolactin (显示 PRL ELISA试剂盒) signaling in the mammary gland.

  7. The results showed that AG490 inhibited (p)-JAK2 and RANKL (显示 TNFSF11 ELISA试剂盒) expression.

  8. these results have revealed that phosphorylation of Tyr (显示 TYR ELISA试剂盒)-343, Tyr (显示 TYR ELISA试剂盒)-460, and Tyr (显示 TYR ELISA试剂盒)-464 in EpoR (显示 EPOR ELISA试剂盒) underlies JAK2 V617F mutant-induced tumorigenesis.

  9. this study shows that ampelopsin reduces inflammatory response of microglial cells through inhibition of JAK2-STAT3 (显示 STAT3 ELISA试剂盒) signaling

  10. At the molecular level, administration of liraglutide induced the expression of PDX-1 (显示 PDX1 ELISA试剂盒), MafA (显示 MAFA ELISA试剂盒), p-JAK2 and p-Stat3 (显示 STAT3 ELISA试剂盒) in high-fat diet-induced diabetes model to relatively normal levels.

Pig (Porcine) Janus Kinase 2 (JAK2) interaction partners

  1. nitration of JAK2 may act as an inhibitory counterpart to phosphorylation activation, reflecting a very localized break on the progression of GH signal transduction processes spanning JAK (显示 JAK3 ELISA试剂盒)-STAT (显示 STAT1 ELISA试剂盒)-AKT (显示 AKT1 ELISA试剂盒) interactions

Cow (Bovine) Janus Kinase 2 (JAK2) interaction partners

  1. Janus kinase 2 (JAK2) gene polymorphism is a potential marker for milk production traits in cattle

  2. Results indicate that SNPs in STAT5A (显示 STAT5A ELISA试剂盒) and JAK2 genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2-STAT5 (显示 STAT5A ELISA试剂盒) and mTOR (显示 FRAP1 ELISA试剂盒) signaling pathways.

  4. SNPs in JAK2 and STAT5B (显示 STAT5B ELISA试剂盒) are associated with mastitis susceptibility in Chinese Holstein cattle

  5. Localized changes in the state of nitration of regulatory phosphorylation domains of JAK2 in caveoLAE during inflammation suggest a unique mechanism through which discrete signal transduction switching might occur in the liver

JAK2 抗原简介

Antigen Summary

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Alternative names and synonyms associated with JAK2

  • Janus kinase 2b (jak2b) Elisa Kit
  • Janus kinase 2 (JAK2) Elisa Kit
  • Janus kinase 2 (Jak2) Elisa Kit
  • tyrosine-protein kinase JAK2-like (LOC100051487) Elisa Kit
  • AI504024 Elisa Kit
  • C81284 Elisa Kit
  • Fd17 Elisa Kit
  • JAK-2 Elisa Kit
  • jak2 Elisa Kit
  • JAK2bCA Elisa Kit
  • JTK10 Elisa Kit
  • THCYT3 Elisa Kit

Protein level used designations for Janus Kinase 2 (JAK2) ELISA试剂盒

Jak2b kinase , PTK JAK2b , protein tyrosine kinase JAK2b , tyrosine-protein kinase JAK2 , JAK-2 , Janus kinase 2 (a protein tyrosine kinase) , tyrosine kinase

GENE ID SPECIES
30298 Danio rerio
3717 Homo sapiens
16452 Mus musculus
24514 Rattus norvegicus
374199 Gallus gallus
484185 Canis lupus familiaris
397201 Sus scrofa
525246 Bos taurus
464979 Pan troglodytes
100172517 Pongo abelii
100051487 Equus caballus
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