anti-JAK2 (JAK2) 抗体产品概述

Full name:
anti-Janus Kinase 2 抗体 (JAK2)
在www.antibodies-online.cn可供280 Janus Kinase 2 (JAK2) 抗体的28不同的供货商。 再加上,我们可以发JAK2 试剂盒 (30)JAK2 蛋白 (25)和数多这个蛋白质的别的产品。 总共349 JAK2产品已列进来了。
别名:
AI504024, C81284, Fd17, JAK-2, jak2, JAK2bCA, JTK10, THCYT3

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引用最多的anti-JAK2 抗体

  1. Human Polyclonal JAK2 Primary Antibody for WB - ABIN265197 : Manning, DiSalvo, Stull: Protein phosphorylation: quantitative analysis in vivo and in intact cell systems. in Molecular and cellular endocrinology 1980 (PubMed)
    Show all 12 references for 265197

  2. Human Polyclonal JAK2 Primary Antibody for FACS, IF - ABIN387982 : Joos, Granzow, Holtgreve-Grez, Siebert, Harder, Martín-Subero, Wolf, Adamowicz, Barth, Lichter, Jauch: Hodgkin's lymphoma cell lines are characterized by frequent aberrations on chromosomes 2p and 9p including REL and JAK2. in International journal of cancer. Journal international du cancer 2002 (PubMed)
    Show all 5 references for 387982

  3. Human Polyclonal JAK2 Primary Antibody for IF, ELISA - ABIN1532352 : Dalal, Arpaia, Dadi, Kulkarni, Squire, Roifman: Cloning and characterization of the human homolog of mouse Jak2. in Blood 1998 (PubMed)
    Show all 2 references for 1532352

  4. Human Polyclonal JAK2 Primary Antibody for IHC, ELISA - ABIN1532914 : Peeters, Raynaud, Cools, Wlodarska, Grosgeorge, Philip, Monpoux, Van Rompaey, Baens, Van den Berghe, Marynen: Fusion of TEL, the ETS-variant gene 6 (ETV6), to the receptor-associated kinase JAK2 as a result of t(9;12) in a lymphoid and t(9;15;12) in a myeloid leukemia. in Blood 1997 (PubMed)
    Show all 2 references for 1532914

  5. Mouse (Murine) Polyclonal JAK2 Primary Antibody for IHC (p), WB - ABIN658412 : Qian, Lin, Yao, Chen, Xiao, Ji, Li, Yang, Qian: Rapid detection of JAK2 V617F mutation using high-resolution melting analysis with LightScanner platform. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)
    Show all 2 references for 658412

  6. Human Polyclonal JAK2 Primary Antibody for EIA, WB - ABIN356677 : Kanda, Watanabe: Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes. in Endocrinology 2007 (PubMed)

更多抗JAK2的相互作用对抗体

Zebrafish Janus Kinase 2 (JAK2) interaction partners

  1. Of two Jak2 paralogues present in zebrafish, Jak2a but not Jak2b is involved in the intracellular transmission of the Ifn-gamma (显示 IFNG 抗体) signal.

Human Janus Kinase 2 (JAK2) interaction partners

  1. Molecular interactions of EphA4 (显示 EPHA4 抗体), growth hormone receptor (显示 GHR 抗体), Jak2, and STAT5B (显示 STAT5B 抗体) have been described.

  2. Peritoneal membrane dysfunction in long-term peritoneal dialysis patients may result from IL-6 (显示 IL6 抗体) promotion of epithelial-to-mesenchymal transition of human peritoneal mesothelial cells possibly through the JAK2/STAT3 (显示 STAT3 抗体) signaling pathway.

  3. Mutation inactivating JAK2 gene is associated with Breast Cancer Metastasis.

  4. mechanical load upregulates expression of Runx2 (显示 RUNX2 抗体) gene via potentiation of PC1 (显示 PCSK1 抗体)-JAK2/STAT3 (显示 STAT3 抗体) signaling axis, culminating to possibly control osteoblastic differentiation and ultimately bone formation.

  5. blocking the ERRalpha (显示 ESRRA 抗体)-controlled mitochondrial program largely inhibits the PLA2R1 (显示 PLA2R1 抗体)-induced tumor-suppressive response. Together, our data document ERRalpha (显示 ESRRA 抗体) and its mitochondrial program as downstream effectors of the PLA2R1 (显示 PLA2R1 抗体)-JAK2 pathway leading to oncosuppression.

  6. JAK2 was overexpressed in Epstein Barr virus-associated gastric adenocarcinoma.

  7. As marrow histology in this murine model of myeloproliferation reveals a preferentially perivascular localization of JAK2(V617F)-mutant megakaryocytes and an increased marrow sinusoid vascular density

  8. mutated FLT3 (显示 FLT3 抗体)-ITD and JAK2 augment reactive oxygen species production and homologous recombination, shifting the cellular milieu toward illegitimate recombination events.

  9. Germ line JAK2 mutations E846D and R1063H are associated with hereditary erythrocytosis with megakaryocytic atypia.

  10. Data suggest that ruxolitinib treatment for up to 4 years provides progressive reductions in Janus kinase 2 (JAK2) p.V617F allele burden in patients with polycythemia vera (显示 IGF2BP3 抗体) (PV).

Mouse (Murine) Janus Kinase 2 (JAK2) interaction partners

  1. Study shows that Jak2 with V617F mutation induces murine model for myeloproliferative neoplasm.

  2. results suggest that loss of Ezh2 (显示 EZH2 抗体) cooperates with Jak2V617F in the development of myelofibrosis in Jak2V617F

  3. JAK2-V617F-expressing mice treated with an Ezh2 (显示 EZH2 抗体) inhibitor showed higher platelet counts than vehicle controls. Our data support the proposed tumor suppressor function of EZH2 (显示 EZH2 抗体)

  4. findings demonstrate that clinically relevant doses of the JAK1 (显示 JAK1 抗体)/2 inhibitor ruxolitinib suppresses the harmful consequences of macrophage overactivation characterizing Hemophagocytic lymphohistiocytosis in 2 murine models.

  5. JAK2 has a role in hepatocarcinogenesis through regulating critical inflammatory pathways

  6. Data show that CUZD1 (显示 CUZD1 抗体) interacts with a complex containing JAK1 (显示 JAK1 抗体)/JAK2 and STAT5 (显示 STAT5A 抗体), downstream transducers of prolactin (显示 PRL 抗体) signaling in the mammary gland.

  7. The results showed that AG490 inhibited (p)-JAK2 and RANKL (显示 TNFSF11 抗体) expression.

  8. these results have revealed that phosphorylation of Tyr (显示 TYR 抗体)-343, Tyr (显示 TYR 抗体)-460, and Tyr (显示 TYR 抗体)-464 in EpoR (显示 EPOR 抗体) underlies JAK2 V617F mutant-induced tumorigenesis.

  9. this study shows that ampelopsin reduces inflammatory response of microglial cells through inhibition of JAK2-STAT3 (显示 STAT3 抗体) signaling

  10. At the molecular level, administration of liraglutide induced the expression of PDX-1 (显示 PDX1 抗体), MafA (显示 MAFA 抗体), p-JAK2 and p-Stat3 (显示 STAT3 抗体) in high-fat diet-induced diabetes model to relatively normal levels.

Pig (Porcine) Janus Kinase 2 (JAK2) interaction partners

  1. nitration of JAK2 may act as an inhibitory counterpart to phosphorylation activation, reflecting a very localized break on the progression of GH signal transduction processes spanning JAK (显示 JAK3 抗体)-STAT (显示 STAT1 抗体)-AKT (显示 AKT1 抗体) interactions

Cow (Bovine) Janus Kinase 2 (JAK2) interaction partners

  1. Janus kinase 2 (JAK2) gene polymorphism is a potential marker for milk production traits in cattle

  2. Results indicate that SNPs in STAT5A (显示 STAT5A 抗体) and JAK2 genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.

  3. Methionine promoted casein synthesis, and this may be mediated by enhanced intracellular substrate availability and by activating JAK2-STAT5 (显示 STAT5A 抗体) and mTOR (显示 FRAP1 抗体) signaling pathways.

  4. SNPs in JAK2 and STAT5B (显示 STAT5B 抗体) are associated with mastitis susceptibility in Chinese Holstein cattle

  5. Localized changes in the state of nitration of regulatory phosphorylation domains of JAK2 in caveoLAE during inflammation suggest a unique mechanism through which discrete signal transduction switching might occur in the liver

JAK2 抗原简介

Antigen Summary

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Alternative names and synonyms associated with JAK2

  • Janus kinase 2b (jak2b) 抗体
  • Janus kinase 2 (JAK2) 抗体
  • Janus kinase 2 (Jak2) 抗体
  • tyrosine-protein kinase JAK2-like (LOC100051487) 抗体
  • AI504024 抗体
  • C81284 抗体
  • Fd17 抗体
  • JAK-2 抗体
  • jak2 抗体
  • JAK2bCA 抗体
  • JTK10 抗体
  • THCYT3 抗体

Protein level used designations for anti-Janus Kinase 2 (JAK2) 抗体

Jak2b kinase , PTK JAK2b , protein tyrosine kinase JAK2b , tyrosine-protein kinase JAK2 , JAK-2 , Janus kinase 2 (a protein tyrosine kinase) , tyrosine kinase

GENE ID SPECIES
30298 Danio rerio
3717 Homo sapiens
16452 Mus musculus
24514 Rattus norvegicus
374199 Gallus gallus
484185 Canis lupus familiaris
397201 Sus scrofa
525246 Bos taurus
464979 Pan troglodytes
100172517 Pongo abelii
100051487 Equus caballus
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