anti-Frog JAK1 抗体 for Immunofluorescence

Recommended JAK1 Antibody (supplied by: Log in to see )

抗原
Janus Kinase 1 (JAK1) 抗体
  • JNK
  • JNK1
  • JAK1
  • jak1
  • JAK1A
  • JAK1B
  • JTK3
  • AA960307
  • C130039L05Rik
  • wu:fb93e10
  • Janus kinase 1
  • mitogen-activated protein kinase 8
  • Tyrosine-protein kinase Jak1
  • JAK1
  • MAPK8
  • jak1
  • Jak1
抗原表位
AA 551-766
29
19
16
15
15
10
7
7
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
适用
小鸡, 犬, Frog, 人, 小鼠, 大鼠
124
101
84
5
5
4
4
1
宿主
小鼠
112
16
9
1
克隆类型
单克隆
标记
This JAK1 antibody is un-conjugated
4
4
3
3
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
应用范围
Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
85
59
48
17
13
13
9
9
5
4
2
1
Supplier
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产品编号 ABIN967842
产品在该地区无法提供。
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中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
12.326117 ABIN967841 IF IP IHC WB Mouse IgG1, kappa AA 551-766 Log in to see 73-JAK1 5

引用最多的anti-JAK1 抗体 for Immunofluorescence

  • Chicken Monoclonal JAK1 Primary Antibody for IF, IP - ABIN967842 (5 Publications): Blesofsky, Mowen, Arduini, Baker, Murphy, Bowtell, David: Regulation of STAT protein synthesis by c-Cbl. in Oncogene 2001 (PubMed)

  • Chicken Monoclonal JAK1 Primary Antibody for IF, IP - ABIN967841 (5 Publications): Kawazoe, Naka, Fujimoto, Kohzaki, Morita, Narazaki, Okumura, Saitoh, Nakagawa, Uchiyama, Akira, Kishimoto: Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation. in The Journal of experimental medicine 2001 (PubMed)

Similar anti-JAK1 抗体

应用范围 / 适用 小鼠 大鼠 小鸡 Frog
Immunofluorescence (fixed cells) (IF/ICC) 3 抗体 3 抗体 2 抗体 1 抗体 1 抗体
Western Blotting (WB) 74 抗体 60 抗体 46 抗体 5 抗体 5 抗体 2 抗体
Immunoprecipitation (IP) 9 抗体 2 抗体 2 抗体 2 抗体 6 抗体 5 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 13 抗体 11 抗体 9 抗体

General

抗原 Janus Kinase 1 (JAK1) 抗体
抗原表位 AA 551-766
(29), (19), (16), (15), (15), (10), (7), (7), (4), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
适用 小鸡, 犬, Frog, 人, 小鼠, 大鼠
(124), (101), (84), (5), (5), (4), (4), (1)
宿主 小鼠
(112), (16), (9), (1)
克隆类型 (克隆位点)
单克隆   ( )
标记 This JAK1 antibody is un-conjugated
(4), (4), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1)
应用范围 Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
(85), (59), (48), (17), (13), (13), (9), (9), (5), (4), (2), (1)
Pubmed 5个引用可参考
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JAK1抗体详情

JAK1目标详情 使用细节 贮存及处理 ProductDetails: References for anti-JAK1 antibody (ABIN967842) 图像
交叉反应 犬, 大鼠, 小鼠, 小鸡, Frog
产品特性 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
4. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
5. For fluorochrome spectra and suitable instrument settings, please refer to us.
纯化方法 The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
免疫原 Human JAK1 aa. 551-766
克隆位点 73-JAK1
亚型 IgG1, kappa

JAK1目标详情

JAK1抗体详情 使用细节 贮存及处理 ProductDetails: References for anti-JAK1 antibody (ABIN967842) 图像 回页首
抗原
别名 JAK1 (JAK1 Antibody 摘要)
背景 The JAK family of receptor-associated protein kinases is directly involved in interferon (IFN) response pathways. The JAK family contains at least three members: JAK1, JAK2, and Tyk2. Each protein is approximately 130 kDa and contains a C-terminal tyrosine kinase domain, an adjacent kinase or kinase-related domain, and five other domains that are highly conserved among family members. In several human and murine cell lines, JAK1 is rapidly tyrosine phosphorylated in response to IFN-alpha and IFN-gamma. JAK1 is required for the phosphorylation of the transcription factor Stat1 (p91), in response to IFNs-alpha or IFN-gamma. JAK1 is also necessary for the efficient phophorylation of Stat2 (p113) in response to IFN-alpha and for the phosphorylation of Tyk2 or JAK2 in response to IFNs-alpha or IFN-gamma, respectively.
分子量 130 kDa
研究领域 Signaling, Cytokines, Receptors, Kinases/Phosphatases
途径 JAK/STAT Signaling, RTK signaling, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades

使用细节

JAK1抗体详情 JAK1目标详情 贮存及处理 ProductDetails: References for anti-JAK1 antibody (ABIN967842) 图像 回页首
说明

Related Products: ABIN968537, ABIN967389

限制 仅限研究用

贮存及处理

JAK1抗体详情 JAK1目标详情 使用细节 ProductDetails: References for anti-JAK1 antibody (ABIN967842) 图像 回页首
状态 Liquid
浓度 250 μg/mL
缓冲液 Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件 -20 °C
储存方法 Store undiluted at -20°C.

ProductDetails: References for anti-JAK1 antibody (ABIN967842)

JAK1抗体详情 JAK1目标详情 使用细节 贮存及处理 图像 回页首
有引用在:

Kopantzev, Heller, Swaminathan, Rudikoff: "IL-6 mediated activation of STAT3 bypasses Janus kinases in terminally differentiated B lineage cells." in: Oncogene, Vol. 21, Issue 44, pp. 6791-800, 2002

Blesofsky, Mowen, Arduini, Baker, Murphy, Bowtell, David: "Regulation of STAT protein synthesis by c-Cbl." in: Oncogene, Vol. 20, Issue 50, pp. 7326-33, 2001

Kawazoe, Naka, Fujimoto, Kohzaki, Morita, Narazaki, Okumura, Saitoh, Nakagawa, Uchiyama, Akira, Kishimoto: "Signal transducer and activator of transcription (STAT)-induced STAT inhibitor 1 (SSI-1)/suppressor of cytokine signaling 1 (SOCS1) inhibits insulin signal transduction pathway through modulating insulin receptor substrate 1 (IRS-1) phosphorylation." in: The Journal of experimental medicine, Vol. 193, Issue 2, pp. 263-9, 2001

Müller, Briscoe, Laxton, Guschin, Ziemiecki, Silvennoinen, Harpur, Barbieri, Witthuhn, Schindler: "The protein tyrosine kinase JAK1 complements defects in interferon-alpha/beta and -gamma signal transduction." in: Nature, Vol. 366, Issue 6451, pp. 129-35, 1993

背景

Nicholson, Oates, Harpur, Ziemiecki, Wilks, Layton: "Tyrosine kinase JAK1 is associated with the granulocyte-colony-stimulating factor receptor and both become tyrosine-phosphorylated after receptor activation." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 91, Issue 8, pp. 2985-8, 1994

图像

JAK1抗体详情 JAK1目标详情 使用细节 贮存及处理 ProductDetails: References for anti-JAK1 antibody (ABIN967842) 回页首
厂商提供的图像
Western Blotting (WB) image for anti-JAK1 抗体 (Janus Kinase 1) (AA 551-766) (ABIN967842) Western blot analysis of JAK1 on Jurkat cell lysate. Lane 1: 1:250, lane 2: 1:500, la...
Immunofluorescence (IF) image for anti-JAK1 抗体 (Janus Kinase 1) (AA 551-766) (ABIN967842) Immunofluorescent staining of Human Endothelial cells.
 image for anti-JAK1 抗体 (Janus Kinase 1) (AA 551-766) (ABIN967842) anti-Janus Kinase 1 (JAK1) (AA 551-766) antibody (Image 3)