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anti-IL21 Receptor (IL21R) 抗体产品概述

Full name:
anti-Interleukin 21 Receptor 抗体 (IL21R)
在www.antibodies-online.cn可供139 Interleukin 21 Receptor (IL21R) 抗体的24不同的供货商。 再加上,我们可以发IL21 Receptor 蛋白 (24)IL21 Receptor 试剂盒 (10)和数多这个蛋白质的别的产品。 总共185 IL21 Receptor产品已列进来了。
别名:
CD360, il-21ra.a, IL21R, NILR
列出全部抗体 基因 基因ID UniProt
IL21R 50615 Q9HBE5
IL21R 60504 Q9JHX3
IL21R 308977  

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引用最多的anti-IL21 Receptor 抗体

  1. Human Monoclonal IL21 Receptor Primary Antibody for FACS - ABIN4896191 : de Totero, Capaia, Fabbi, Croce, Meazza, Cutrona, Zupo, Loiacono, Truini, Ferrarini, Ferrini: Heterogeneous expression and function of IL-21R and susceptibility to IL-21-mediated apoptosis in follicular lymphoma cells. in Experimental hematology 2010 (PubMed)
    Show all 5 references for ABIN4896191

  2. Mouse (Murine) Monoclonal IL21 Receptor Primary Antibody for BR, FACS - ABIN2663782 : Mehta, Wurster, Grusby: Biology of IL-21 and the IL-21 receptor. in Immunological reviews 2004 (PubMed)
    Show all 4 references for ABIN2663782

  3. Mouse (Murine) Monoclonal IL21 Receptor Primary Antibody for IF - ABIN2659037 : Jin, Carrio, Yu, Malek: Distinct activation signals determine whether IL-21 induces B cell costimulation, growth arrest, or Bim-dependent apoptosis. in Journal of immunology (Baltimore, Md. : 1950) 2004 (PubMed)
    Show all 3 references for ABIN2659037

  4. Human Monoclonal IL21 Receptor Primary Antibody for FACS - ABIN4899489 : Ansén, Butler, Berezovskaya, Murray, Stevenson, Nadler, Hirano: Dissociation of its opposing immunologic effects is critical for the optimization of antitumor CD8+ T-cell responses induced by interleukin 21. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Show all 3 references for ABIN4899489

  5. Mouse (Murine) Monoclonal IL21 Receptor Primary Antibody for FACS - ABIN4896193 : Caruso, Fina, Peluso, Fantini, Tosti, Del Vecchio Blanco, Paoluzi, Caprioli, Andrei, Stolfi, Romano, Ricci, MacDonald, Pallone, Monteleone: IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)
    Show all 2 references for ABIN4896193

  6. Human Polyclonal IL21 Receptor Primary Antibody for FACS, WB - ABIN4899487 : Alves, Arosa, van Lier: IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells. in Journal of immunology (Baltimore, Md. : 1950) 2005 (PubMed)

  7. Human Polyclonal IL21 Receptor Primary Antibody for EIA, IHC (p) - ABIN499988 : Parrish-Novak, Dillon, Nelson, Hammond, Sprecher, Gross, Johnston, Madden, Xu, West, Schrader, Burkhead, Heipel, Brandt, Kuijper, Kramer, Conklin, Presnell, Berry, Shiota, Bort, Hambly, Mudri, Clegg et al.: Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. ... in Nature 2000 (PubMed)

  8. Human Monoclonal IL21 Receptor Primary Antibody for FACS - ABIN4896189 : Zhang, Tao, Chopra, Dujmovic-Basuroski, Jin, Tang, Drulovic, Markovic-Plese: IL-11 Induces Th17 Cell Responses in Patients with Early Relapsing-Remitting Multiple Sclerosis. in Journal of immunology (Baltimore, Md. : 1950) 2015 (PubMed)

  9. Human Polyclonal IL21 Receptor Primary Antibody for IF (p), IHC (p) - ABIN748148 : Guan, Wang, Meng, Shi, Jiang, Xiao, Shi, Xu, Zhang: Increased IL-21/IL-21R expression and its proinflammatory effects in autoimmune thyroid disease. in Cytokine 2015 (PubMed)

更多抗IL21 Receptor的相互作用对抗体

Horse (Equine) Interleukin 21 Receptor (IL21R) interaction partners

  1. IL21R is probably not causally involved in recurrent airway obstruction.

Human Interleukin 21 Receptor (IL21R) interaction partners

  1. bone marrow monocytes from multiple myeloma patients show distinct features compared to those from patients with indolent monoclonal gammopathies, supporting the role of IL21R over-expression by bone marrow CD14 (显示 NDUFA2 抗体)(+) cells in enhanced osteoclast formation.

  2. Report increased levels of IL-21R in the skeletal muscle endothelial cells of patients with peripheral arterial disease compared to control individuals.

  3. expression of IL-21 (显示 IL17C 抗体) and IL-21R were up-regulated in autoimmune thyroid disease and may be involved in the pathogenesis of the disease through augmenting aberrant immune cascade

  4. interleukin-21 receptor deficiency is associated with Severe Combined Immunodeficiency (显示 PRKDC 抗体).

  5. IL-21R on B cells is upregulated in allergic rhinitis patients when compared to controls. IL-21/IL-21R may be involved in the regulation of allergic reactions through the inhibition of IgE.

  6. IL-21 (显示 IL17C 抗体)/IL-21R could act as potential biomarkers presenting early systemic sclerosis skin lesions severity.

  7. STAT3 (显示 STAT3 抗体) signaling downstream of IL-23R (显示 IL23R 抗体) and IL-21R has a role in controlling human mucosal-associated invariant T cells and NKT (显示 SLC22A6 抗体) cell numbers

  8. Human neutrophils in peripheral blood express functional IL-21 (显示 IL17C 抗体) receptors.

  9. IL-21R gene polymorphisms and serum IL-21 (显示 IL17C 抗体) levels predict virological response to interferon (显示 IFNA 抗体)-based therapy in Asian chronic hepatitis C patients.

  10. Abundant expression of interleukin-21 receptor in follicular lymphoma cells is associated with more aggressive disease.

Mouse (Murine) Interleukin 21 Receptor (IL21R) interaction partners

  1. IL-21 (显示 IL21 抗体) may play an important role in the pathogenesis of SSc (显示 CYP11A1 抗体) as a Th17 effector cytokine, and IL-21 (显示 IL21 抗体) may induce the differentiation of Th17 cells in the BLM-induced systemic sclerosis mouse model via Il21R.

  2. Gene expression analyses of angioimmunoblastic T-cell lymphoma (AITL), showed that essentially all cases expressed elevated levels of transcripts for IL21 (显示 IL21 抗体), IL21R, and a series of genes associated with TFH cell development and function.

  3. IIl21r deletion reduced spontaneous EAE associated with defective Th17 cell generation. IL-21R deficiency limited IL-23R (显示 IL23R 抗体) expression on Th17 cells and inhibited expression of key molecules for pathogenic Th17 cell generation.

  4. our data demonstrate the novel finding that the IL-21R plays a critical role in regulating innate immune responses against HSV-2 infection.

  5. During experimental arthritis, IL-21R deficiency protected against severe inflammation and joint destruction. This was accompanied by suppressed serum IgG1 levels and antigen-specific T cell responses.

  6. in the absence of IL-21 (显示 IL21 抗体)/IL-21R signaling, Il2 (显示 IL2 抗体)(-/-) mice retained a deficiency in Tregs yet exhibited a reduced and delayed inflammatory disease which was reflected in reduced pancreatitis and hemolytic anemia

  7. IL-21R expression on donor CD4 (显示 CD4 抗体)+ T cells is essential for sustaining T cell number and help for B cells, resulting in more severe lupus-like renal disease, but it does not alter the balance of T helper (Th)17 cells and regulatory T cells.

  8. IL-21R controls both antigen transport by DCs and the crucial beacon (显示 UBL5 抗体) function of CD4 (显示 CD4 抗体)(+) cells for autoreactive CD8 (显示 CD8A 抗体)(+) cells to reach the islets.

  9. Data indicate that CD8KO recipients given either C57Bl/6 or IL-21RKO CD8 (显示 CD8A 抗体)+ cells showed the recipients given C57Bl/6 CD8 (显示 CD8A 抗体)+ cells with significantly greater myocarditis than recipients of IL-21RKO CD8 (显示 CD8A 抗体)+ cells.

  10. IL-21 (显示 IL21 抗体) and IL-2 (显示 IL2 抗体) can have overlapping roles in promoting conventional T-cell responses but play distinct roles in controlling Treg homeostasis and function.

IL21 Receptor (IL21R) 抗原简介

Antigen Summary

The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with IL21 Receptor (IL21R)

  • interleukin 21 receptor (IL21R) 抗体
  • interleukin 21 receptor (il21r) 抗体
  • interleukin 21 receptor (Il21r) 抗体
  • CD360 抗体
  • il-21ra.a 抗体
  • IL21R 抗体
  • NILR 抗体

Protein level used designations for IL21R

interleukin-21 receptor , interleukin 21 receptor , interleukin 21 receptor alpha.a , IL-21 receptor , novel interleukin receptor , IL-21R , LR-beta , NR8 , lymphocyte receptor beta , novel cytokine receptor 8

GENE ID SPECIES
416586 Gallus gallus
454006 Pan troglodytes
608011 Canis lupus familiaris
705759 Macaca mulatta
100066814 Equus caballus
100134976 Danio rerio
100450175 Pongo abelii
100467688 Ailuropoda melanoleuca
100601027 Nomascus leucogenys
50615 Homo sapiens
60504 Mus musculus
617967 Bos taurus
308977 Rattus norvegicus
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