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Human IL15 ELISA Kit for Sandwich ELISA - ABIN625012
Shoman, Nabil, Tabl, Ghanem, Kafrawy: Assessment of immunological changes in Epstein-Barr virus co-infection in Egyptian chronic HCV patients. in Memórias do Instituto Oswaldo Cruz 2014
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Rat (Rattus) IL15 ELISA Kit for Sandwich ELISA - ABIN416368
Molanouri Shamsi, Hassan, Gharakhanlou, Quinn, Azadmanesh, Baghersad, Isanejad, Mahdavi: Expression of interleukin-15 and inflammatory cytokines in skeletal muscles of STZ-induced diabetic rats: effect of resistance exercise training. in Endocrine 2014
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Rat (Rattus) IL15 ELISA Kit for Sandwich ELISA - ABIN365261
Zanchi, Lira, de Siqueira Filho, Rosa, de Oliveira Carvalho, Seelaender, Santos, Lancha: Chronic low frequency/low volume resistance training reduces pro-inflammatory cytokine protein levels and TLR4 mRNA in rat skeletal muscle. in European journal of applied physiology 2010
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Human IL15 ELISA Kit for Sandwich ELISA - ABIN414877
Shi, Liu, Zhang, Guo, Song, Song, Liu: miR-15b is Downregulated in Myasthenia Gravis Patients and Directly Regulates the Expression of Interleukin-15 (IL-15) in Experimental Myasthenia Gravis Mice. in Medical science monitor : international medical journal of experimental and clinical research 2015
Mouse (Murine) IL15 ELISA Kit for Sandwich ELISA - ABIN625405
Collignon, Perles-Barbacaru, Robert, Silvy, Martinez, Crenon, Germain, Garcia, Viola, Lombardo, Mas, Béraud: A pancreatic tumor-specific biomarker characterized in humans and mice as an immunogenic onco-glycoprotein is efficient in dendritic cell vaccination. in Oncotarget 2015
Mouse (Murine) IL15 ELISA Kit for Sandwich ELISA - ABIN365238
Yin, Xu, Sun, Wei, Tian: Interleukin-15 suppresses hepatitis B virus replication via IFN-? production in a C57BL/6 mouse model. in Liver international : official journal of the International Association for the Study of the Liver 2012
Human IL15 ELISA Kit for Sandwich ELISA - ABIN2684586
Conti, Frappier, Dharancy, Chereau, Houssin, Weill, Calmus: Interleukin-15 production during liver allograft rejection in humans. in Transplantation 2003
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T cells in chimpanzees infected with human immunodeficiency virus express surface interleukin-15.
CD3 (显示 CD3 ELISA试剂盒)(-) CD8 (显示 CD8A ELISA试剂盒)(+) NK cells play a vital role in controlling HIV-1 infection by producing high levels of IFN-gamma (显示 IFNG ELISA试剂盒), and that IL-15 elicits IFN-gamma (显示 IFNG ELISA试剂盒) production in this subpopulation of NK cells in HIV-1-infected chimpanzees. [Il-15, CD8 (显示 CD8A ELISA试剂盒) antigen, IFN-gamma (显示 IFNG ELISA试剂盒)]
results demonstrate that IL-15 and RANKL (显示 TNFSF11 ELISA试剂盒) induce osteoclastogenesis synergistically, and IL-15 might play a novel and major role in destructive inflammatory bone diseases
This study provides mechanistic insight into how IL-15 controls the generation of memory CD8 (显示 CD8A ELISA试剂盒) T cells and influences their trafficking and ability to take up residence within peripheral tissues.
findings extend understanding of the differential modes of action between IL-2 (显示 IL2 ELISA试剂盒) and IL-15, and highlight how, although sharing the CD122 (显示 IL2RB ELISA试剂盒)/CD132 (显示 IL2RG ELISA试剂盒) receptor, they elicit such different immune actions
IL-15 induced by inflammatory signals in response to lymphodepletion drives lymphocyte responses, as memory CD8 (显示 CD8A ELISA试剂盒) T cells proliferated in an IL-15-dependent manner.
these findings unveil a role for IL-15 as a critical mediator in defense against systemic candidiasis and hold promise for the design of IL-15-based antifungal immunotherapies.
developmental arrest of Natural killer cells results from a lack of IL-15 availability in the microenvironment.
IL-15 impacts butyrate-producing bacteria and lowers butyrate levels in the absence of overt pathology, which represent events that precede and promote intestinal inflammatory diseases.
endogenous IL-15 does not directly augment the pathogenesis of sepsis but enables the development of septic shock by maintaining NK cell numbers and integrity.
this study shows that IL-15-mediated control of the precursor population affects the development of virus-specific CD8 (显示 CD8A ELISA试剂盒)+ T-cell memory
this study shows that unleashed trans-presentation of IL-15 on MyD88 (显示 MYD88 ELISA试剂盒)-deficient fibroblastic reticular cells during viral infection fosters the activation of cytotoxic and non-cytotoxic group 1 innate lymphoid cells and accelerates clearance of the virus
High IL15 expression is associated with endometriosis.
IL-15 drives bystander activation of CD8 (显示 CD8A ELISA试剂盒)+ T cells, which predicts disease progression in untreated HIV-1-infected patients and suggests that elevated IL-15 may also drive CD8 (显示 CD8A ELISA试剂盒)+ T cell expansion that is linked to increased morbidity and mortality in treated patients
Sustained virologic response was significantly associated with IL15 rs10833 in chronic hepatitis C patients, treated with pegylated interferon-alpha (显示 IFNA ELISA试剂盒) and ribavirin.
IL-15 mRNA and protein levels significantly increased in rhHBcAg stimulation group compared with non-stimulated group.
this work provides evidence that the sushi-IL-15Ralpha/IL-15 fusion protein RLI (显示 ABCE1 ELISA试剂盒) enhances antitumor activity of anti-PD-1 (显示 PDCD1 ELISA试剂盒) treatment and is a promising approach to stimulate host immunity
These results reveal a novel role of IL-7 (显示 IL7 ELISA试剂盒) and IL-15 in maintaining human T cell function, provide an explanation for T cell dysfunction in humanized mice, and have significant implications for in vitro studies with human T cells.
This analysis revealed highly connected functional interaction networks with two candidate genes, IL15 and SEC14L5 highly enriched in networks. Overall, from these results, we concluded that these genes can be recommended as some of the potential targets for Post-Traumatic Stress Disorder.
These data support a potential role for IL-15 in the pathogenesis of HIV-associated immune activation.
Cutaneous T-cell lymphoma (CTCL (显示 TSPYL2 ELISA试剂盒)) pathogenesis remains unknown, and there are no curative therapies. Our findings not only demonstrate a critical role for IL15-mediated inflammation in cutaneous T-cell lymphomagenesis, but also uncover a new oncogenic regulatory loop in CTCL (显示 TSPYL2 ELISA试剂盒) involving IL15, HDAC1 (显示 HDAC1 ELISA试剂盒), HDAC6 (显示 HDAC6 ELISA试剂盒), and miR (显示 MLXIP ELISA试剂盒)-21 that shows differential sensitivity to isotype-specific HDAC (显示 HDAC3 ELISA试剂盒) inhibitors
Myokine IL-15 regulates the crosstalk of co-cultured porcine skeletal muscle satellite cells and preadipocytes.
results demonstrate that porcine reproductive and respiratory syndrome virus (PRRSV)infection could induce IL-15 production in macrophages/dendritic cells; data further show that upregulation of IL-15 by PRRSV requires PKC (显示 FYN ELISA试剂盒) and NF-kappaB (显示 NFKB1 ELISA试剂盒) pathways
IFN-gamma (显示 IFNG ELISA试剂盒) targets the adipocyte to induce IL-15 expression, thus indicating a possible role for the adipocyte in the regulation of T-cell function and muscle metabolism during the innate immune response
When induced by IFN-gamma (显示 IFNG ELISA试剂盒) or other inflammatory mediators, IL-15 may be a significant homeorhetic factor that mobilizes and directs energy away from the adipocyte to other cells during the acute phase of the inflammatory response.
Increased function and survival of IL-15-transduced dendritic cells are mediated by up-regulation of IL-15Ralpha and Bcl-2 (显示 BCL2 ELISA试剂盒).
IL 15 generates a dramatic expansion of short-lived memory CD8 (显示 CD8A ELISA试剂盒) T cells and natural killer in immunocompetent macaques and has long-term effects on the balance of CD4 (显示 CD4 ELISA试剂盒)(+) and CD8 (显示 CD8A ELISA试剂盒)(+) T cells.
These data suggest that therapeutic use of IL-15 in the setting of antiretroviral therapy might facilitate specific restoration of the CD4 (显示 CD4 ELISA试剂盒) + T cell compartment.
IL-15 secretion significantly correlates with the up-regulated expression of CD4 (显示 CD4 ELISA试剂盒) on memory CD4 (显示 CD4 ELISA试剂盒) T cells that is associated with increased permissiveness to simian immunodeficiency virus infection.
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported.