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Human IL12B ELISA Kit for Sandwich ELISA - ABIN411311
Becher, Durell, Noelle: Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12. in The Journal of clinical investigation 2002
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Mouse (Murine) IL12B ELISA Kit for Sandwich ELISA - ABIN1305259
Chougnet, Freitag, Schito, Thomas, Sher, Shearer: In vivo CD40-CD154 (CD40 ligand) interaction induces integrated HIV expression by APC in an HIV-1-transgenic mouse model. in Journal of immunology (Baltimore, Md. : 1950) 2001
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Mouse (Murine) IL12B ELISA Kit for Sandwich ELISA - ABIN1672845
Cua, Sherlock, Chen, Murphy, Joyce, Seymour, Lucian, To, Kwan, Churakova, Zurawski, Wiekowski, Lira, Gorman, Kastelein, Sedgwick: Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. in Nature 2003
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Human IL12B ELISA Kit for Sandwich ELISA - ABIN1446078
Vilisaar, Kawabe, Braitch, Aram, Furtun, Fahey, Chopra, Tanasescu, Tighe, Gran, Pothoulakis, Constantinescu: Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis. in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 2015
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Human IL12B ELISA Kit for Sandwich ELISA - ABIN625009
Chowdhury, Ahmed, Choudhuri, Sen, Hazra, Pal, Bhattacharya, Bahar: Alteration of serum inflammatory cytokines in active pulmonary tuberculosis following anti-tuberculosis drug therapy. in Molecular immunology 2014
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Human IL12B ELISA Kit for Sandwich ELISA - ABIN2684574
Sieburth, Jabs, Warrington, Li, Lasota, LaForgia, Kelleher, Huebner, Wasmuth, Wolf: Assignment of genes encoding a unique cytokine (IL12) composed of two unrelated subunits to chromosomes 3 and 5. in Genomics 1992
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Rat (Rattus) IL12B ELISA Kit for Sandwich ELISA - ABIN416325
Hou, Zhu, Sun, Ma, Wang, Timothy, Chen, Yan, Lei, Han, Chen, Cai, Guan: Serum Proteomics Analysis in Rats of Immunosuppression Induced by Chronic Stress. in Scandinavian journal of immunology 2016
Horse (Equine) IL12B ELISA Kit for Sandwich ELISA - ABIN416683
Duran, Willenbrock, Müller, Nolte, Feige, Murua Escobar: Establishment and evaluation of a bead-based luminex assay allowing simultaneous quantification of equine IL-12 and IFN-?. in Anticancer research 2013
All the tested TLRAs induced greater infant IFN-alpha2 (显示 IFNA2 ELISA试剂盒) production compared to newborn and adult blood. In contrast, CpG induced greater IFN-gamma (显示 IFNG ELISA试剂盒), IL-1beta (显示 IL1B ELISA试剂盒), IL-4 (显示 IL4 ELISA试剂盒), IL-12p40, IL-10 (显示 IL10 ELISA试剂盒) and CXCL8 (显示 IL8 ELISA试剂盒) in newborn than in infant and adult blood.
Simultaneous elevated circulating levels of IL-18 (显示 IL18 ELISA试剂盒) and IL-12 (显示 IL12A ELISA试剂盒) increased the event rate after 2 years in Coronary Artery Disease patients, independent of hyperglycemia
Single-nucleotide-polymorphisms of IL12B may be considered a high-risk factor for Takayasu arteritis in Chinese Han population
IL-12B -1188 C allele may be a protective factor against asthma in East Asians
The low expression of HDAC3 (显示 HDAC3 ELISA试剂盒) and overexpession of inflammatory cytokines (IL-18 (显示 IL18 ELISA试剂盒), IL-12 (显示 IL12A ELISA试剂盒) and TNF-alpha (显示 TNF ELISA试剂盒)) in intrahepatic cholestasis of pregnancy may be involved in liver cell apoptosis and in the pathophysiology of the disease.
Polymorphisms of IFNG (显示 IFNG ELISA试剂盒), IL12B and IL12RB1 (显示 IL12RB1 ELISA试剂盒) genes in paracoccidioidomycosis Brazilian patients do not affect the susceptibility or resistance to the disease.
Identification of PARP-1 (显示 PARP1 ELISA试剂盒) as a unique regulator of Il12b transcription in response to inflammatory insults in an allele-differentiating manner
Pre-incubation with IL-12 (显示 IL12A ELISA试剂盒) was able to restore IFN-gamma (显示 IFNG ELISA试剂盒) production and the cytotoxicity capacities of NK cells. This cytokine may therefore be considered as a potential treatment candidate in traumatic brain injury patients with immune suppression.
NOD2 (显示 NOD2 ELISA试剂盒) rs3135500 and IL12B rs1368439 SNPs were not genetic risk factors for colorectal cancer in the studied Iranian population.
assembly-induced folding is key in IL-12 (显示 IL12A ELISA试剂盒) family biogenesis and secretion; the identification of essential disulfide bonds that underlie this process lays the basis for a simplified yet functional IL-12 (显示 IL12A ELISA试剂盒) cytokine
Data indicate that there was a differential transcription of 381 genes which changed greater than two fold in B1a of p40-/-IL-2Ralpha-/- mice.
this study shows that a systemic IL-12 (显示 IL12A ELISA试剂盒) primes intestinal cells that became more prone to develop inflammatory responses, which is long-lasting because intestinal cells maintain their inflammatory potential and their ability to aggravate colitis
this study shows that endosomal signalling by Lactobacillus acidophilus that leads to IL-12 (显示 IL12A ELISA试剂盒) production is inhibited by TLR stimulation from the plasma membrane
Irradiation-induced IL-6 (显示 IL6 ELISA试剂盒) can decrease IL-12 (显示 IL12A ELISA试剂盒) production through the inhibition of C-Rel (显示 NFkBP65 ELISA试剂盒) phosphorylation by the IL-6 (显示 IL6 ELISA试剂盒)/STAT3 (显示 STAT3 ELISA试剂盒) signaling pathway.
The IL-12 (显示 IL12A ELISA试剂盒) response by dendritic cells against S. aureus is highly growth phase dependent.
the PI3K pathway mediated IL-12 (显示 IL12A ELISA试剂盒) inhibition but did not interfere with the inhibition of IL-23 (显示 IL23A ELISA试剂盒) or stimulation of IL-10 (显示 IL10 ELISA试剂盒).
Data indicate that sera from treated with cholesterol-p40 (Il12b)-siRNA contained significantly reduced concentrations of p40.
this study demonstrates viral RNA analog-induced transcription synergy of Il6 (显示 IL6 ELISA试剂盒) and Il12b via IFN regulatory factor (IRF)1 (显示 IRF1 ELISA试剂盒) (TLR3 (显示 TLR3 ELISA试剂盒)-TIR domain-containing adaptor inducing IFN-beta (显示 TICAM1 ELISA试剂盒) [TRIF (显示 RNF138 ELISA试剂盒)] responsive), C/EBPbeta (显示 CEBPB ELISA试剂盒) (TLR7 (显示 TLR7 ELISA试剂盒)-MyD88 (显示 MYD88 ELISA试剂盒) responsive), and JunB (显示 JUNB ELISA试剂盒) (all responsive).
These findings reveal a critical role for IL-12 (显示 IL12A ELISA试剂盒) in shaping the anti-inflammatory biofilm milieu by promoting MDSC recruitment.
our results suggest that IL-12p40 acts as a negative regulator of autoimmune cholangitis in IL-2Ralpha-/- mice. Compared to IL-2Ralpha-/- mice, p40-/-IL-2Ralpha-/- mice develop liver fibrosis and reduced colitis.
Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (显示 TNF ELISA试剂盒), IL-6 (显示 IL6 ELISA试剂盒), IL-12p40, IL-1beta (显示 IL1B ELISA试剂盒), and resulted in increased expression of the apoptosis initiator caspase-8 (显示 CASP8 ELISA试剂盒) and bcl2L1 (显示 BCL2L1 ELISA试剂盒).
The results showed that the expression of TNF-alpha (显示 TNF ELISA试剂盒), iNOS (显示 NOS2 ELISA试剂盒), and IL-6 (显示 IL6 ELISA试剂盒) in alveolar macrophages was up-regulated by stimulation with the recombinant Mce4A protein of M. bovis; in contrast, expression of IL-12 (显示 IL12A ELISA试剂盒) was unaffected.[IL-6 (显示 IL6 ELISA试剂盒), IL-12 (显示 IL12A ELISA试剂盒)]
study investigated hypothesis that CD40 (显示 CD40 ELISA试剂盒) signalling is impaired in Mycobacterium avium subspecies paratuberculosis(MAP)-infected macrophages; propose that MAP interferes with gene expression of iNOS (显示 NOS2 ELISA试剂盒) and IL-12p40 genes downstream of p38 (显示 MAPK14 ELISA试剂盒)
In rhesus macaques plasmacytoid dendritic cells in peripheral blood express IL-12p40 upon TLR-7 (显示 TLR7 ELISA试剂盒)/8 and TLR-9 (显示 TLR9 ELISA试剂盒) stimulation, which could potentially affect their response to vaccination and viral infection.
This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children.
, IL-12 subunit p40
, IL12, subunit p40
, NK cell stimulatory factor chain 2
, cytotoxic lymphocyte maturation factor 40 kDa subunit
, interleukin 12, p40
, interleukin-12 beta chain
, interleukin-12 subunit beta
, natural killer cell stimulatory factor, 40 kD subunit
, CLMF p35
, IL-12 subunit p35
, cytotoxic lymphocyte maturation factor 35 kDa subunit
, interleukin 12
, interleukin-12 subunit alpha
, IL-12 p40
, IL-23 subunit p40
, interleukin-12 p40
, interleukin-12 p40 subunit
, interleukin 12B
, interleukin-12 p35 subunit
, IL-12 p40 subunit
, interleukin 12 p40.b
, interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
, interleukin 12Ba (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
, interleukin 12 p40 subunit
, interleukin-12 p40 chain
, interleukin 12 40kDa subunit
, Cytotoxic lymphocyte maturation factor 40 kDa subunit
, Interleukin-12 subunit beta