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Human IL-13 ELISA Kit for Sandwich ELISA - ABIN625011
Zurawski, de Vries: Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. in Immunology today 1994
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Mouse (Murine) IL-13 ELISA Kit for Sandwich ELISA - ABIN625137
Chung, Park, Park: Anti-inflammatory effects of low-molecular weight chitosan oligosaccharides in IgE-antigen complex-stimulated RBL-2H3 cells and asthma model mice. in International immunopharmacology 2012
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Guinea Pig IL-13 ELISA Kit for Sandwich ELISA - ABIN364909
Maarsingh, Dekkers, Zuidhof, Bos, Menzen, Klein, Flik, Zaagsma, Meurs: Increased arginase activity contributes to airway remodelling in chronic allergic asthma. in The European respiratory journal 2011
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Pig (Porcine) IL-13 ELISA Kit for Sandwich ELISA - ABIN415833
Baker, Romero, Bach, Strom, Gamelli, Majetschak: Systemic release of cytokines and heat shock proteins in porcine models of polytrauma and hemorrhage*. in Critical care medicine 2012
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Rat (Rattus) IL-13 ELISA Kit for Sandwich ELISA - ABIN416369
Fang, Li, Liang, Xue, Liu, Yang, Gao, Jiang: Downregulation of SUMF2 gene in ovalbumin-induced rat model of allergic inflammation. in International journal of clinical and experimental pathology 2016
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Mouse (Murine) IL-13 ELISA Kit for Sandwich ELISA - ABIN411312
Wang, Shen, Li, Zhang, Luo, Zhong, Jiang, Shen: Enhanced expression of the decoy receptor IL-13Ralpha2 in macrophages of Schistosoma japonicum-infected mice. in Chinese medical journal 2009
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Dog (Canine) IL-13 ELISA Kit for Sandwich ELISA - ABIN414189
Majewska, Gajewska, Dembele, Maciejewski, Prostek, Jank: Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis. in BMC veterinary research 2016
Mouse (Murine) IL-13 ELISA Kit for Sandwich ELISA - ABIN415504
Fang, Shi, Wu, Zhang, Zhong, Deng, Zhang, Xie: Targeted inhibition of GATA-6 attenuates airway inflammation and remodeling by regulating caveolin-1 through TLR2/MyD88/NF-κB in murine model of asthma. in Molecular immunology 2016
Horse (Equine) IL-13 ELISA Kit for Sandwich ELISA - ABIN416685
Mariella, Castagnetti, Prosperi, Scagliarini, Peli: Cytokine levels in colostrum and in foals' serum pre- and post-suckling. in Veterinary immunology and immunopathology 2017
Human IL-13 ELISA Kit for Sandwich ELISA - ABIN1446080
Liu, Weir, Busse, Yang, Zhou, Emala, Li: The Flavonoid 7,4'-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-?B, STAT6, and HDAC2. in Phytotherapy research : PTR 2015
the IL13-1112 C/T (rs1800925) polymorphism does not predict responsiveness to neoadjuvant chemoradiotherapy or prognosis of Chinese Han patients with locally advanced rectal cancer .
Different genotype profiles of IL13 gene seem to influence the clinical pattern of disease expression mainly confined to the upper airways, as rhinitis, or including the lower airways, as asthma
secretion of IL-13 and amphiregulin (显示 AREG ELISA试剂盒) suggests Intrahepatic Innate lymphoid cells may be recruited to promote resolution and repair and thereby they may contribute to ongoing fibrogenesis in liver disease.
Increased baseline mRNA levels of the Th2-related cytokine IL-13 and the regulatory cytokine IL-10 (显示 IL10 ELISA试剂盒) predicted a positive food challenge outcome.
These findings demonstrate that NF-kappaB (显示 NFKB1 ELISA试剂盒)-mediated transcriptional mechanisms are critically involved in the IL-1beta (显示 IL1B ELISA试剂盒)-mediated IL-17C (显示 IL17C ELISA试剂盒) induction, and that IL-13 negatively regulates this induction by suppressing NF-kappaB (显示 NFKB1 ELISA试剂盒)-based transcriptional activation.
These results suggested that IL-13 +1923C/T polymorphism contributed to the development of asthma.
IL13 AA of rs20541 and STAT4 (显示 STAT4 ELISA试剂盒) TT of rs925847 are potential genomic biomarkers for predicting lower pulmonary function. The administration of high-dose ICSs to asthmatic patients with genetic variants of IL13 AA may inhibit the advancement of airway remodelling. The genetic variants of STAT4 (显示 STAT4 ELISA试剂盒) TT did not respond to high-dose ICSs.
The diagnostic performance of sputum IL-13 was superior to both sputum eosinophils and FeNO levels for the identification of well-controlled asthma. Sputum IL-13 levels could serve as a useful biomarker for asthma control assessment.
15LO1 inhibition (by short interfering RNA and chemical inhibitor) decreased IL-13-induced forkhead box protein A3 (FOXA3 (显示 FOXA3 ELISA试剂盒)) expression and enhanced FOXA2 (显示 FOXA2 ELISA试剂盒) expression. These changes were associated with reductions in both mucin 5AC and periostin (显示 POSTN ELISA试剂盒).
Clarithromycin suppressed IL-13-induced periostin (显示 POSTN ELISA试剂盒) production in human lung fibroblasts, in part by inhibiting STAT6 (显示 STAT6 ELISA试剂盒) phosphorylation. This suggests a novel mechanism of the immunomodulatory effect of clarithromycin in asthmatic airway inflammation and fibrosis.
Data indicate that interleukin-33 (IL-33 (显示 IL33 ELISA试剂盒))-induced Interleukin-13 (IL-13) production by type-2 helper T cells (Th2 cells) Is dependent on epidermal growth factor receptor (EGFR (显示 EGFR ELISA试剂盒)) expression.
this study shows that environmental IL-13 plays a role in conditioning early thymic progenitors lineage choice, which would impact T cell development
IL-4 (显示 IL4 ELISA试剂盒) and IL-13 are required to effectively polarize macrophages/dendritic cells to an M2a phenotype and to promote recovery from acute kidney injury.
this study shows that ST2 (显示 SULT2A1 ELISA试剂盒) regulates early IL-13 production in fungus-induced allergic airway inflammation
These observations suggest that IL-4 (显示 IL4 ELISA试剂盒) and IL-13 likely operate through the Heteroreceptor and influence Th17 cells to convert to Th1 (显示 HAND1 ELISA试剂盒) cells and to acquire increased sensitivity to suppression, leading to control of immune-mediated CNS inflammation.
MIF (显示 MIF ELISA试剂盒)-deficient mice have reduced Nippostrongylus brasiliensis burden and mounted an enhanced type 2 immune response, including increased Gata3 (显示 GATA3 ELISA试剂盒) expression and IL-13 production in the mesenteric lymph nodes
findings suggest that a leukotriene B4 receptor-2 (显示 LTB4R2 ELISA试剂盒)-linked cascade plays a pivotal role in LPS/TLR4 (显示 TLR4 ELISA试剂盒) signaling for IL-13 synthesis in mast cells, thereby potentially exacerbating allergic response.
Study found IL-13 to be critically involved in the development of chemical-induced asthma, as shown by using IL-13 KO mice, and more specifically in the effector phase as confirmed by anti- IL-13 antibody treatment.
these studies show that fibrosis, steatosis, cholestasis, and ductular reaction are simultaneously controlled but distinctly regulated by interleukin-13 signaling
Our data support that impaired clearance of inhaled allergens triggering IL-13 production by multiple cell types in the airways plays an important role in the pathogenesis of type 2 airway inflammation and suggests therapeutic improvement of mucociliary clearance as a novel treatment strategy for children with allergen-induced asthma.
T helper (Th) type 2 cell cytokine IL-13 modulates airway contraction by secreting matrix metalloproteinase-1 (显示 MMP1 ELISA试剂盒) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
, T-cell activation protein P600