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Human IL-13 ELISA Kit for Sandwich ELISA - ABIN625011
Zurawski, de Vries: Interleukin 13, an interleukin 4-like cytokine that acts on monocytes and B cells, but not on T cells. in Immunology today 1994
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Mouse (Murine) IL-13 ELISA Kit for Sandwich ELISA - ABIN625137
Chung, Park, Park: Anti-inflammatory effects of low-molecular weight chitosan oligosaccharides in IgE-antigen complex-stimulated RBL-2H3 cells and asthma model mice. in International immunopharmacology 2012
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Pig (Porcine) IL-13 ELISA Kit for Sandwich ELISA - ABIN415833
Baker, Romero, Bach, Strom, Gamelli, Majetschak: Systemic release of cytokines and heat shock proteins in porcine models of polytrauma and hemorrhage*. in Critical care medicine 2012
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Rat (Rattus) IL-13 ELISA Kit for Sandwich ELISA - ABIN416369
Fang, Li, Liang, Xue, Liu, Yang, Gao, Jiang: Downregulation of SUMF2 gene in ovalbumin-induced rat model of allergic inflammation. in International journal of clinical and experimental pathology 2016
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Guinea Pig IL-13 ELISA Kit for Sandwich ELISA - ABIN364909
Maarsingh, Dekkers, Zuidhof, Bos, Menzen, Klein, Flik, Zaagsma, Meurs: Increased arginase activity contributes to airway remodelling in chronic allergic asthma. in The European respiratory journal 2011
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Horse (Equine) IL-13 ELISA Kit for Sandwich ELISA - ABIN416685
Mariella, Castagnetti, Prosperi, Scagliarini, Peli: Cytokine levels in colostrum and in foals' serum pre- and post-suckling. in Veterinary immunology and immunopathology 2017
Mouse (Murine) IL-13 ELISA Kit for Sandwich ELISA - ABIN415504
Fang, Shi, Wu, Zhang, Zhong, Deng, Zhang, Xie: Targeted inhibition of GATA-6 attenuates airway inflammation and remodeling by regulating caveolin-1 through TLR2/MyD88/NF-κB in murine model of asthma. in Molecular immunology 2016
Dog (Canine) IL-13 ELISA Kit for Sandwich ELISA - ABIN414189
Majewska, Gajewska, Dembele, Maciejewski, Prostek, Jank: Lymphocytic, cytokine and transcriptomic profiles in peripheral blood of dogs with atopic dermatitis. in BMC veterinary research 2016
Human IL-13 ELISA Kit for Sandwich ELISA - ABIN1446080
Liu, Weir, Busse, Yang, Zhou, Emala, Li: The Flavonoid 7,4'-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-?B, STAT6, and HDAC2. in Phytotherapy research : PTR 2015
Mouse (Murine) IL-13 ELISA Kit for Sandwich ELISA - ABIN411312
Wang, Shen, Li, Zhang, Luo, Zhong, Jiang, Shen: Enhanced expression of the decoy receptor IL-13Ralpha2 in macrophages of Schistosoma japonicum-infected mice. in Chinese medical journal 2009
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Leptin (显示 LEP ELISA试剂盒) knockdown suppressed MUC5AC production and secretion induced by IL-13 in human bronchial epithelial cells.
demonstrate a strong association between the ratio of Acinetobacter to Proteobacteria and IL-13 production and the probability of IL-13 production after allergen exposure. IL-13 concentrations in serum were also significantly correlated with the diversity of bacterial DNA. Together, these results underscore the relationship between immune responses to allergens and bacterial exposure during perinatal development.
These observations suggest that mechanical stretch may induce an influx of Ca(2 (显示 CA2 ELISA试剂盒)+) and up-regulation of IL-13 and MMP-9 (显示 MMP9 ELISA试剂盒) expression in 16HBE cells via activation of TRPC1 (显示 TRPC1 ELISA试剂盒)
Studies show that bronchoalveolar lavage fluid (BALF) soluble triggering receptor expressed on myeloid cells-1 (显示 TREM1 ELISA试剂盒) (sTREM-1) levels do not discriminate between mild-to-moderate asthma and chronic obstructive pulmonary disease (COPD (显示 ARCN1 ELISA试剂盒)), in contrast, the interleukin 6 (IL-6 (显示 IL6 ELISA试剂盒))/interleukine 13 (IL-13) ratio measured in BALF effectively differentiated these two diseases.
The presented data substantiate the hypothesis that claudin-18 (显示 CLDN18 ELISA试剂盒) is a central barrier-forming component of tight junctions and show that IL-13 downregulates claudin-18 (显示 CLDN18 ELISA试剂盒). These data also suggest that the loss of claudin-18 (显示 CLDN18 ELISA试剂盒) is associated with increased sensitization to aeroantigens and airway responsiveness
IL-12 pretreatment increased TCR-induced IFN-gamma, TNF-alpha, IL-13, IL-4 and IL-10 production. This suggests that prior exposure to IL-12 potentiates the TCR-induced release of a range of cytokines
Studies in colonic T84 cell monolayers revealed that barrier disruption by the colitis-associated Th2-type cytokines, IL-4 (显示 IL4 ELISA试剂盒) and IL-13, down-regulates matriptase (显示 ST14 ELISA试剂盒) as well as prostasin (显示 PRSS8 ELISA试剂盒) through phosphorylation of the transcriptional regulator STAT6 (显示 STAT6 ELISA试剂盒)
investigated the role of six potentially functional variants of the IL4 (显示 IL4 ELISA试剂盒), IL13, and IL4R (显示 IL4R ELISA试剂盒) genes in gastrointestinal cancer; both IL13 rs20541 and rs1800925 were not associated with gastrointestinal cancer risk for any of the genetic models and subgroup analyses [meta-analysis]
IL13 in bronchial epithelial cells and bronchial alveolar lavage fluid, rather than RAD50 (显示 RAD50 ELISA试剂盒), IL4 (显示 IL4 ELISA试剂盒), or IL5 (显示 IL5 ELISA试剂盒), is more likely to be the asthma susceptibility gene.
We also found that the activation of H4R (显示 HRH4 ELISA试剂盒) caused the release of IL-13 and RANTES (显示 CCL5 ELISA试剂盒) on human mast cells.these data demonstrate that the H4R (显示 HRH4 ELISA试剂盒) activates divergent signaling pathways to induce cytokine and chemokine (显示 CCL1 ELISA试剂盒) production in human mast cells
MIF (显示 MIF ELISA试剂盒)-deficient mice have reduced Nippostrongylus brasiliensis burden and mounted an enhanced type 2 immune response, including increased Gata3 (显示 GATA3 ELISA试剂盒) expression and IL-13 production in the mesenteric lymph nodes
findings suggest that a leukotriene B4 receptor-2 (显示 LTB4R2 ELISA试剂盒)-linked cascade plays a pivotal role in LPS/TLR4 (显示 TLR4 ELISA试剂盒) signaling for IL-13 synthesis in mast cells, thereby potentially exacerbating allergic response.
Study found IL-13 to be critically involved in the development of chemical-induced asthma, as shown by using IL-13 KO mice, and more specifically in the effector phase as confirmed by anti- IL-13 antibody treatment.
these studies show that fibrosis, steatosis, cholestasis, and ductular reaction are simultaneously controlled but distinctly regulated by interleukin-13 signaling
Our data support that impaired clearance of inhaled allergens triggering IL-13 production by multiple cell types in the airways plays an important role in the pathogenesis of type 2 airway inflammation and suggests therapeutic improvement of mucociliary clearance as a novel treatment strategy for children with allergen-induced asthma.
this study shows that wild-type mice develop an eosinophilic Th2 airway disease in response to Alternaria alternata exposure, whereas IL-13-deficient mice exhibit a primarily neutrophilic response
this study shows that IL-17A (显示 IL17A ELISA试剂盒) contributes to asthma pathophysiology by increasing the capacity of IL-13 to activate intracellular signaling pathways, such as STAT6 (显示 STAT6 ELISA试剂盒) activation
RCM-1 (显示 TNNI3 ELISA试剂盒) reduced IL-13 and STAT6 (signal transducer and activator of transcription 6 (显示 STAT6 ELISA试剂盒)) signaling and prevented the expression of the STAT6 (显示 STAT6 ELISA试剂盒) target genes Spdef and Foxa3 (显示 FOXA3 ELISA试剂盒), which are key transcriptional regulators of goblet cell differentiation.
IL-13 suppressed both the activation-induced apoptosis of CD4 (显示 CD4 ELISA试剂盒)(+) T cells and the expression of p53 (显示 TP53 ELISA试剂盒) and FasL (显示 FASL ELISA试剂盒).
We clearly show that miR (显示 MLXIP ELISA试剂盒)-155 has a previously unknown direct regulatory role in the ILC2 subset that affects IL-33 (显示 IL33 ELISA试剂盒) receptor expression, IL-33 (显示 IL33 ELISA试剂盒) responsiveness, and IL-13 production as well as proliferation capability, possibly due to defects in GATA-3 (显示 GATA3 ELISA试剂盒) function.
T helper (Th) type 2 cell cytokine IL-13 modulates airway contraction by secreting matrix metalloproteinase-1 (显示 MMP1 ELISA试剂盒) from the smooth muscle cells via phosphatidylinositol 3-kinase activation and changing cell-to-matrix interactions.
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.
, T-cell activation protein P600