Use your antibodies-online credentials, if available.
Select your species
Human IFNB1 ELISA Kit for Sandwich ELISA - ABIN414734
Li, Li, Qian, Zhang, Chen, Shi: Impaired TLR3/IFN-beta signaling in monocyte-derived dendritic cells from patients with acute-on-chronic hepatitis B liver failure: relevance to the severity of liver damage. in Biochemical and biophysical research communications 2009
Show all 10 Pubmed References
Horse (Equine) IFNB1 ELISA Kit for Sandwich ELISA - ABIN416691
Waldschmidt, Pirottin, Art, Audigié, Bureau, Tosi, El Abbas, Farnir, Richard, Dupuis: Experimental model of equine alveolar macrophage stimulation with TLR ligands. in Veterinary immunology and immunopathology 2013
Show all 6 Pubmed References
Mouse (Murine) IFNB1 ELISA Kit for Sandwich ELISA - ABIN415550
Kang, Kim, Choi, Kim, Lee: Scoparone attenuates D-galactosamine/lipopolysaccharide-induced fulminant hepatic failure through inhibition of toll-like receptor 4 signaling in mice. in Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2013
Show all 3 Pubmed References
Rhesus Monkey IFNB1 ELISA Kit for Sandwich ELISA - ABIN415337
Bosinger, Johnson, Folkner, Patel, Hashempour, Jochems, Del Rio Estrada, Paiardini, Lin, Vanderford, Hiscott, Silvestri: Intact type I Interferon production and IRF7 function in sooty mangabeys. in PLoS pathogens 2013
Show all 3 Pubmed References
Chicken IFNB1 ELISA Kit for Sandwich ELISA - ABIN414096
Feng, Dai, Xie, Li, Shi, Zhang: Innate Immune Responses in ALV-J Infected Chicks and Chickens with Hemangioma In Vivo. in Frontiers in microbiology 2016
Show all 2 Pubmed References
Rat (Rattus) IFNB1 ELISA Kit for Sandwich ELISA - ABIN416262
Kang, Koh, Lee: Melatonin protects liver against ischemia and reperfusion injury through inhibition of toll-like receptor signaling pathway. in Journal of pineal research 2011
Show all 2 Pubmed References
Cow (Bovine) IFNB1 ELISA Kit for Competition ELISA - ABIN577538
Zhang, Fu, Deng, Xie, Xu, Liu, Hu, Chen, Guo: Attenuation of bovine herpesvirus type 1 by deletion of its glycoprotein G and tk genes and protection against virulent viral challenge. in Vaccine 2011
Show all 2 Pubmed References
Pig (Porcine) IFNB1 ELISA Kit for Sandwich ELISA - ABIN415826
Liu, Yang, Zhao, Dong, Gou, Pei, Chen: PKR activation enhances replication of classical swine fever virus in PK-15 cells. in Virus research 2015
Mouse (Murine) IFNB1 ELISA Kit for Sandwich ELISA - ABIN366343
Yin, Xu, Sun, Wei, Tian: Interleukin-15 suppresses hepatitis B virus replication via IFN-? production in a C57BL/6 mouse model. in Liver international : official journal of the International Association for the Study of the Liver 2012
Pig (Porcine) IFNB1 ELISA Kit for Sandwich ELISA - ABIN365282
Cruz, Becares, Sola, Oliveros, Enjuanes, Zúñiga: Alphacoronavirus protein 7 modulates host innate immune response. in Journal of virology 2013
either JC1 or DS1 C/EBP site is sufficient to mediate IFN beta-induced down-regulation of SIV long terminal repeat activity and virus replication in macrophages
Hepatitis A virus protein 2B suppresses beta interferon (显示 IFNA ELISA试剂盒) (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.
BVDV2-E significantly increased IFN-beta activity compared to BVDV2-wt.
The data confirm the involvement of EHMT2 (显示 EHMT2 ELISA试剂盒) in the epigenetic regulation of IFN-b and demonstrate the activation of a general antiviral state after EHMT2 (显示 EHMT2 ELISA试剂盒) inhibition.
The authors provide evidence that ICP27 protein encoded by bovine herpesvirus type 1, a viral early protein that shuttles between the nucleus and cytoplasm inhibits transcriptional activity of two bovine IFN-beta gene promoters (IFN-beta1 and IFN-beta3).
The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta promoter activity and induces IRF3 (显示 IRF3 ELISA试剂盒) degradation.
These studies provide evidence that virus infection differentially stimulates expression of the three bovine IFN-beta genes.
recombinant bovine respiratory syncytial virus lacking the NS proteins, and those lacking NS2 in particular, are strong inducers of IFN-alpha (显示 IFNA ELISA试剂盒)/beta in bovine nasal fibroblasts and bronchoalveolar macrophages.
Extracellular ATP reduces the replication of VSV, Newcastle disease virus, murine leukemia virus and HSV in vivo and in vitro through the P2X7 receptor (显示 P2RX7 ELISA试剂盒); ATP increases IFN-beta expression. Mechanistically, ATP facilitates IFN-beta secretion through P38 (显示 CRK ELISA试剂盒)/JNK (显示 MAPK8 ELISA试剂盒)/ATF-2 (显示 ATF2 ELISA试剂盒) signaling pathways, which are crucial in promoting antiviral immunity.
study reports that mitochondrial antiviral signaling protein (MAVS (显示 MAVS ELISA试剂盒)), -mediated IFN-alpha (显示 IFNA ELISA试剂盒)/beta production and IFNAR (显示 IFNAR1 ELISA试剂盒) signaling are required for alloimmune responses to the human K1 Ag in a murine model of inflammation-induced alloimmunization
study identifies a novel role for RIPK1 (显示 RIPK1 ELISA试剂盒) and RIPK3 (显示 RIPK3 ELISA试剂盒), a pair of homologous serine/threonine kinases previously implicated in the regulation of necroptosis and pathologic tissue injury, in directing IFN-beta production in macrophages
results suggest that, in addition to its well-known signaling activity, IFN-beta may be directly antimicrobial and be part of a growing family of cytokines and chemokines, called kinocidins, that also have antimicrobial properties.
results show that resistance to HSV-1 in the trigeminal ganglia during acute infection is conferred in part by STING and IFN-alpha (显示 IFNA ELISA试剂盒)/beta signaling in both bone marrow-derived and -resident cells, which coalesce to support a robust HSV-1-specific CD8 (显示 CD8A ELISA试剂盒)(+) T cell response
RIPK3 (显示 RIPK3 ELISA试剂盒) regulates type I IFN both transcriptionally, by interacting with MAVS (显示 MAVS ELISA试剂盒) and limiting RIPK1 (显示 RIPK1 ELISA试剂盒) interaction with MAVS (显示 MAVS ELISA试剂盒), and post-transcriptionally.
neddylation contributes to HSV-1-induced early phase IFN-beta production.
Rubicon specifically interacts with the interferon (显示 IFNA ELISA试剂盒) regulatory factor (IRF (显示 TRIM63 ELISA试剂盒)) association domain (IAD) of IRF3 (显示 IRF3 ELISA试剂盒), and this interaction leads to inhibition of the dimerization of IRF3 (显示 IRF3 ELISA试剂盒), which negatively regulates interferon (显示 IFNA ELISA试剂盒)-mediated antiviral response.
Translation arrest is further demonstrated to be key for anti-viral response by acting synergistically with MAVS (显示 MAVS ELISA试剂盒) activation to amplify TBK1 (显示 TBK1 ELISA试剂盒) signaling and IFN-beta mRNA transcription, while GADD34 (显示 PPP1R15A ELISA试剂盒)-dependent protein synthesis recovery contributes to the heterogeneous expression of interferon (显示 IFNA ELISA试剂盒) observed in dsRNA-activated cells.
The authors report that Raf kinase inhibitory protein (RKIP (显示 PEBP1 ELISA试剂盒)) is essential for TBK1 (显示 TBK1 ELISA试剂盒) activation and type I interferon (显示 IFNA ELISA试剂盒) production triggered by viral infection.
this study shows that the IFN-beta/STAT1 (显示 STAT1 ELISA试剂盒) pathway is dysregulated in inflammatory bowel disease
results demonstrate that Sphingosine 1-phosphate lyase (SPL (显示 SGPL1 ELISA试剂盒)) is a host factor that augments type I IFN responses during influenza A virus infection; study delineates the relationship between IKKepsilon (显示 IKBKE ELISA试剂盒) and SPL (显示 SGPL1 ELISA试剂盒), which provides a mechanistic understanding of the pro-IFN activity of SPL (显示 SGPL1 ELISA试剂盒)
This study demonstrates a novel pathway for elevated IFNbeta signaling in SLE that is not dependent on stimulation by immune complexes but rather is cell intrinsic and critically mediated by IFNbeta and MAVS (显示 MAVS ELISA试剂盒).
G45R mutation of NS1 (显示 PTPN11 ELISA试剂盒) slightly decreased NS1 (显示 PTPN11 ELISA试剂盒) binding to dsRNA but did not interfere with its suppression of RIG-I (显示 DDX58 ELISA试剂盒)-mediated type I IFN production.
Upon influenza virus infection, DPF2 dysregulated IFN-beta induction and expression of cytokines/chemokines and antiviral proteins. This study provides evidence that influenza virus utilizes DPF2 to escape host innate immunity.
Overexpression of PKV VP3 blocked IFN-beta-induced activation of the STAT1 (显示 STAT1 ELISA试剂盒)/STAT2 (显示 STAT2 ELISA试剂盒)/IRF9 (显示 IRF9 ELISA试剂盒) promoter in a dose-dependent manner.
Data suggest that EV71 infection in enterocytes does not inhibit phosphorylation of STAT1 (显示 STAT1 ELISA试剂盒)/2 induced by IFN-beta, but p-STAT1 (显示 STAT1 ELISA试剂盒)/2 transport into the nucleus is significantly blocked; EV71 infection in enterocytes down-regulates expression of KPNA1 (显示 KPNA1 ELISA试剂盒) and induces degradation of cellular KPNA1 (显示 KPNA1 ELISA试剂盒) via caspase-3 (显示 CASP3 ELISA试剂盒). [EV17 = Enterovirus 71]
This study reveals that decreased induction of both PKR (显示 PKLR ELISA试剂盒) and p300 (显示 EP300 ELISA试剂盒) proteins contribute to impaired induction of IFN-beta in Chronic obstructive pulmonary disease primary bronchial epithelial cells upon influenza infection.
Together, these results suggest that RSV infection of MSCs alters their immune regulatory function by upregulating IFN-b and IDO (显示 IDO1 ELISA试剂盒), affecting immune cell proliferation, which may account for the lack of protective RSV immunity and for chronicity of RSV-associated lung diseases such as asthma and COPD (显示 ARCN1 ELISA试剂盒).
Nuclear export of NSP1alpha of porcine reproductive and respiratory syndrome virus was necessary for its ability for IFN beta inhibition.
Porcine deltacoronavirus nsp5, the 3C-like protease, inhibits interferon-beta production through the cleavage of NEMO (显示 IKBKG ELISA试剂盒).
Highly pathogenic Porcine reproductive and respiratory syndrome virus modulates Interferon-beta expression mainly through attenuating IRF-3 (显示 IRF3 ELISA试剂盒) phosphorylation.
Porcine epidemic diarrhea virus nsp1 inhibited the IFN-beta and IRF3 (显示 IRF3 ELISA试剂盒) promoter activities.
poIFIT3 plays a significant role in the clearance of swine influenza virus in pigs and potentiates IFN-beta production.
DDX41 (显示 DDX41 ELISA试剂盒) is involved in the dsDNA- and dsDNA-virus-mediated type IFN-beta signaling pathway in porcine kidney cells.
VIral NS4 (显示 SOS1 ELISA试剂盒) protein antagonizes beta interferon (显示 IFNA ELISA试剂盒) expression by targeting the NF-kappaB (显示 NFKB1 ELISA试剂盒) essential modulator.
Swine IFN-beta promotes genetic mutation of porcine reproductive and respiratory syndrome virus.
Expression of LSm14A (显示 LSM14A ELISA试剂盒) in HEK293 or Marc (显示 CCL7 ELISA试剂盒)-145 cells enhanced activities of IFN-beta and NF-kappaB (显示 NFKB1 ELISA试剂盒) promoters, induced IFN-beta transcription, and potentiated IFN-beta promoter activation, indicating that LSm14A (显示 LSM14A ELISA试剂盒) is a potential signal molecule (显示 WNT4 ELISA试剂盒) in the IFN-beta pathway.
Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha (显示 IFNA ELISA试剂盒)/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha (显示 IFNA ELISA试剂盒) in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.
suppresses the growth of rat glioma cells
, interferon beta 1
, interferon, beta 1, fibroblast
, IFN-alpha/beta receptor 2
, interferon alpha/beta receptor 2
, interferon, beta; receptor
, interferon-alpha/beta receptor 2
, interferon-alpha/beta receptor beta chain
, type I interferon receptor 2
, interferon, beta 1
, fibroblast interferon
, interferon type B
, interferon beta-1