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抗Mouse (Murine) IFNB1 抗体:
抗Rat (Rattus) IFNB1 抗体:
抗Human IFNB1 抗体:
Human Polyclonal IFNB1 Primary Antibody for ELISA, ICC - ABIN4321105
Colonna: TLR pathways and IFN-regulatory factors: to each its own. in European journal of immunology 2007
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Chicken Polyclonal IFNB1 Primary Antibody for Func, IP - ABIN2474124
Sick, Schultz, Staeheli: A family of genes coding for two serologically distinct chicken interferons. in The Journal of biological chemistry 1996
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Human Polyclonal IFNB1 Primary Antibody for IHC, ELISA - ABIN1002472
Gresser: Wherefore interferon? in Journal of leukocyte biology 1997
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Human Polyclonal IFNB1 Primary Antibody for IP, IHC - ABIN285830
Matsumoto, Takahashi, Shiva, Kawanishi, Kremenik, Kato, Yano: The reduction of voluntary physical activity after poly I:C injection is independent of the effect of poly I:C-induced interferon-beta in mice. in Physiology & behavior 2008
Human Monoclonal IFNB1 Primary Antibody for ELISA - ABIN2474122
Horie, Miyazaki, Nonogi, Takizawa, Nagao, Nishida, Kubota, Kawai: Kinetic analyses of creatine kinase release patterns in patients with acute myocardial infarction undergoing emergency coronary arteriography. in Japanese circulation journal 1990
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Human Polyclonal IFNB1 Primary Antibody for IF (p), IHC (p) - ABIN728158
Quek, Luff, Cheung, Kozlov, Gatei, Lee, Bellingham, Noakes, Lim, Barnett, Dingwall, Wolvetang, Mashimo, Roberts, Lavin: Rats with a missense mutation in Atm display neuroinflammation and neurodegeneration subsequent to accumulation of cytosolic DNA following unrepaired DNA damage. in Journal of leukocyte biology 2016
either JC1 or DS1 C/EBP site is sufficient to mediate IFN beta-induced down-regulation of SIV long terminal repeat activity and virus replication in macrophages
Hepatitis A virus protein 2B suppresses beta interferon (显示 IFNA 抗体) (IFN) gene transcription by interfering with IFN regulatory factor 3 activation.
BVDV2-E significantly increased IFN-beta activity compared to BVDV2-wt.
The data confirm the involvement of EHMT2 (显示 EHMT2 抗体) in the epigenetic regulation of IFN-b and demonstrate the activation of a general antiviral state after EHMT2 (显示 EHMT2 抗体) inhibition.
The authors provide evidence that ICP27 protein encoded by bovine herpesvirus type 1, a viral early protein that shuttles between the nucleus and cytoplasm inhibits transcriptional activity of two bovine IFN-beta gene promoters (IFN-beta1 and IFN-beta3).
The authors demonstrate that bovine herpesvirus 1 bICP0 effectively inhibits bovine IFN-beta promoter activity and induces IRF3 (显示 IRF3 抗体) degradation.
These studies provide evidence that virus infection differentially stimulates expression of the three bovine IFN-beta genes.
recombinant bovine respiratory syncytial virus lacking the NS proteins, and those lacking NS2 in particular, are strong inducers of IFN-alpha (显示 IFNA 抗体)/beta in bovine nasal fibroblasts and bronchoalveolar macrophages.
The data demonstrate that an atypical TLR7 (显示 TLR7 抗体) signaling pathway contributes to type interferon-beta expression during Y. pestis infection and suggest that the TLR7 (显示 TLR7 抗体)-driven type I IFN response plays an important role in determining the outcome of plague.
Long-term exposure to atmospheric particulates, PM2.5 up-regulated H3K4 and H3K9 methylation in IL-6 (显示 IL6 抗体) and IFN-beta promoter regions through down-regulating Kdm6a (显示 KDM6A 抗体) expression. The results suggest that short-term exposure to PM2.5 significantly enhances the survival rate of influenza A-contaminated mice, while long-term PM2.5 inhalation lowers the capacity of pulmonary macrophages to secrete IL-6 (显示 IL6 抗体) and IFN-beta.
Extracellular ATP reduces the replication of VSV, Newcastle disease virus, murine leukemia virus and HSV in vivo and in vitro through the P2X7 receptor (显示 P2RX7 抗体); ATP increases IFN-beta expression. Mechanistically, ATP facilitates IFN-beta secretion through P38 (显示 CRK 抗体)/JNK (显示 MAPK8 抗体)/ATF-2 (显示 ATF2 抗体) signaling pathways, which are crucial in promoting antiviral immunity.
study reports that mitochondrial antiviral signaling protein (MAVS (显示 MAVS 抗体)), -mediated IFN-alpha (显示 IFNA 抗体)/beta production and IFNAR (显示 IFNAR1 抗体) signaling are required for alloimmune responses to the human K1 Ag in a murine model of inflammation-induced alloimmunization
study identifies a novel role for RIPK1 (显示 RIPK1 抗体) and RIPK3 (显示 RIPK3 抗体), a pair of homologous serine/threonine kinases previously implicated in the regulation of necroptosis and pathologic tissue injury, in directing IFN-beta production in macrophages
results suggest that, in addition to its well-known signaling activity, IFN-beta may be directly antimicrobial and be part of a growing family of cytokines and chemokines, called kinocidins, that also have antimicrobial properties.
results show that resistance to HSV-1 in the trigeminal ganglia during acute infection is conferred in part by STING and IFN-alpha (显示 IFNA 抗体)/beta signaling in both bone marrow-derived and -resident cells, which coalesce to support a robust HSV-1-specific CD8 (显示 CD8A 抗体)(+) T cell response
RIPK3 (显示 RIPK3 抗体) regulates type I IFN both transcriptionally, by interacting with MAVS (显示 MAVS 抗体) and limiting RIPK1 (显示 RIPK1 抗体) interaction with MAVS (显示 MAVS 抗体), and post-transcriptionally.
neddylation contributes to HSV-1-induced early phase IFN-beta production.
Rubicon (显示 KIAA0226 抗体) specifically interacts with the interferon (显示 IFNA 抗体) regulatory factor (IRF (显示 TRIM63 抗体)) association domain (IAD) of IRF3 (显示 IRF3 抗体), and this interaction leads to inhibition of the dimerization of IRF3 (显示 IRF3 抗体), which negatively regulates interferon (显示 IFNA 抗体)-mediated antiviral response.
this study shows that the IFN-beta/STAT1 (显示 STAT1 抗体) pathway is dysregulated in inflammatory bowel disease
results demonstrate that Sphingosine 1-phosphate lyase (SPL (显示 SGPL1 抗体)) is a host factor that augments type I IFN responses during influenza A virus infection; study delineates the relationship between IKKepsilon (显示 IKBKE 抗体) and SPL (显示 SGPL1 抗体), which provides a mechanistic understanding of the pro-IFN activity of SPL (显示 SGPL1 抗体)
This study demonstrates a novel pathway for elevated IFNbeta signaling in SLE that is not dependent on stimulation by immune complexes but rather is cell intrinsic and critically mediated by IFNbeta and MAVS (显示 MAVS 抗体).
G45R mutation of NS1 (显示 PTPN11 抗体) slightly decreased NS1 (显示 PTPN11 抗体) binding to dsRNA but did not interfere with its suppression of RIG-I (显示 DDX58 抗体)-mediated type I IFN production.
Upon influenza virus infection, DPF2 dysregulated IFN-beta induction and expression of cytokines/chemokines and antiviral proteins. This study provides evidence that influenza virus utilizes DPF2 to escape host innate immunity.
Overexpression of PKV VP3 blocked IFN-beta-induced activation of the STAT1 (显示 STAT1 抗体)/STAT2 (显示 STAT2 抗体)/IRF9 (显示 IRF9 抗体) promoter in a dose-dependent manner.
Data suggest that EV71 infection in enterocytes does not inhibit phosphorylation of STAT1 (显示 STAT1 抗体)/2 induced by IFN-beta, but p-STAT1 (显示 STAT1 抗体)/2 transport into the nucleus is significantly blocked; EV71 infection in enterocytes down-regulates expression of KPNA1 (显示 KPNA1 抗体) and induces degradation of cellular KPNA1 (显示 KPNA1 抗体) via caspase-3 (显示 CASP3 抗体). [EV17 = Enterovirus 71]
This study reveals that decreased induction of both PKR (显示 PKLR 抗体) and p300 (显示 EP300 抗体) proteins contribute to impaired induction of IFN-beta in Chronic obstructive pulmonary disease primary bronchial epithelial cells upon influenza infection.
Together, these results suggest that RSV infection of MSCs alters their immune regulatory function by upregulating IFN-b and IDO (显示 IDO1 抗体), affecting immune cell proliferation, which may account for the lack of protective RSV immunity and for chronicity of RSV-associated lung diseases such as asthma and COPD (显示 ARCN1 抗体).
Nuclear export of NSP1alpha of porcine reproductive and respiratory syndrome virus was necessary for its ability for IFN beta inhibition.
Porcine deltacoronavirus nsp5 (显示 SPECC1 抗体), the 3C-like protease, inhibits interferon-beta production through the cleavage of NEMO (显示 IKBKG 抗体).
Highly pathogenic Porcine reproductive and respiratory syndrome virus modulates Interferon-beta expression mainly through attenuating IRF-3 (显示 IRF3 抗体) phosphorylation.
Porcine epidemic diarrhea virus nsp1 inhibited the IFN-beta and IRF3 (显示 IRF3 抗体) promoter activities.
poIFIT3 plays a significant role in the clearance of swine influenza virus in pigs and potentiates IFN-beta production.
DDX41 (显示 DDX41 抗体) is involved in the dsDNA- and dsDNA-virus-mediated type IFN-beta signaling pathway in porcine kidney cells.
VIral NS4 (显示 SOS1 抗体) protein antagonizes beta interferon (显示 IFNA 抗体) expression by targeting the NF-kappaB (显示 NFKB1 抗体) essential modulator.
Swine IFN-beta promotes genetic mutation of porcine reproductive and respiratory syndrome virus.
Expression of LSm14A (显示 LSM14A 抗体) in HEK293 or Marc (显示 CCL7 抗体)-145 cells enhanced activities of IFN-beta and NF-kappaB (显示 NFKB1 抗体) promoters, induced IFN-beta transcription, and potentiated IFN-beta promoter activation, indicating that LSm14A (显示 LSM14A 抗体) is a potential signal molecule (显示 WNT4 抗体) in the IFN-beta pathway.
Overall, data provide evidence for the possible role of PI3K in the activation of the transcription of IFN-alpha (显示 IFNA 抗体)/beta by PRRSV; study concludes that PRRSV inhibits the induction of IFN-alpha (显示 IFNA 抗体) in monocyte-derived dendritic cells by as yet undefined post-transcriptional mechanisms.
suppresses the growth of rat glioma cells
, interferon beta 1
, interferon, beta 1, fibroblast
, IFN-alpha/beta receptor 2
, interferon alpha/beta receptor 2
, interferon, beta; receptor
, interferon-alpha/beta receptor 2
, interferon-alpha/beta receptor beta chain
, type I interferon receptor 2
, interferon, beta 1
, fibroblast interferon
, interferon type B
, interferon beta-1