anti-GNAQ (GNAQ) 抗体产品概述

Full name:
anti-Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide 抗体 (GNAQ)
在www.antibodies-online.cn可供85 Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) 抗体的19不同的供货商。 再加上,我们可以发GNAQ 蛋白 (13)GNAQ 试剂盒 (1)和数多这个蛋白质的别的产品。 总共108 GNAQ产品已列进来了。
别名:
1110005L02Rik, 6230401I02Rik, AA408290, AW060788, CMC1, Dsk1, Dsk10, g-alpha-q, Galphaq, gaq, Gnaq, gnaqb, Gq, GqI, si:ch73-270f14.2, SWS

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引用最多的anti-GNAQ 抗体

  1. Chicken Monoclonal GNAQ Primary Antibody for IF, WB - ABIN968914 : Dutt, Kjoller, Giel, Hall, Toksoz: Activated Galphaq family members induce Rho GTPase activation and Rho-dependent actin filament assembly. in FEBS letters 2002 (PubMed)
    Show all 3 references for 968914

  2. Human Polyclonal GNAQ Primary Antibody for WB - ABIN658100 : Klenke, Tan, Hahn, Mann, Hauner, Manthey, Peters, Siffert, Frey: A functional GNAQ promoter haplotype is associated with altered Gq expression and with insulin resistance and obesity in women with polycystic ovary syndrome. in Pharmacogenetics and genomics 2010 (PubMed)
    Show all 2 references for 658100

  3. Human Polyclonal GNAQ Primary Antibody for ELISA, WB - ABIN4315225 : Ngai, Inngjerdingen, Berge, Taskén: Interplay between the heterotrimeric G-protein subunits Galphaq and Galphai2 sets the threshold for chemotaxis and TCR activation. in BMC immunology 2009 (PubMed)

  4. Cow (Bovine) Polyclonal GNAQ Primary Antibody for WB - ABIN2785811 : Arnaud-Lopez, Usala, Ceresini, Mitchell, Pilia, Piras, Sestu, Maschio, Busonero, Albai, Dei, Lai, Mulas, Crisponi, Tanaka, Bandinelli, Guralnik, Loi, Balaci, Sole, Prinzis, Mariotti, Shuldiner, Cao, Schlessinger, Uda, Abecasis, Nagaraja, Sanna, Naitza: Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. in American journal of human genetics 2008 (PubMed)

更多抗GNAQ的相互作用对抗体

Human Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. The findings of the work indicate a role for Galphaq and/or Galpha14 and in CCR2a/CCR2b (显示 CCR2 抗体)-stimulated Rho A (显示 RHOA 抗体) GTPase (显示 RACGAP1 抗体)-mediated serum response factor activation.

  2. GNAQ/11 mutant clones make up a fraction of the cells in choroidal nevi. Nevus cells are furthermore characterised by heterogeneous YAP (显示 YAP1 抗体) expression. Combined GNAQ/11 and YAP (显示 YAP1 抗体) may constitute a putative precursor tumour pathway with an activated oncogene (显示 RAB1A 抗体) (GNAQ/11) and downstream effector (YAP (显示 YAP1 抗体)).

  3. RasGRP3 (显示 RASGRP3 抗体) mediates ERK MAPK (显示 MAPK1 抗体) pathway activation in GNAQ mutant uveal melanoma.

  4. Galphaq regulates the development of rheumatoid arthritis by modulating Th1 (显示 TH1L 抗体) differentiation

  5. The GC/GC (显示 GC 抗体) genotype of the TT(-695/-694)GC polymorphism is associated with increased Gq protein expression, augmented angiotensin II receptor type 1 (显示 AGTR1 抗体)-related vasoconstriction, and increased myocardial injury after coronary artery bypass grafting.

  6. we find iris melanomas to be related genetically to choroidal and ciliary body melanomas, frequently harboring GNAQ, GNA11 (显示 GNA11 抗体), and EIF1AX (显示 EIF1AX 抗体) mutations.

  7. Data suggest that allosteric communication between heterodimeric AT1R and PTGFR is mediated through GNAQ and may also involve proximal phospholipase C but not distal protein kinase C signaling partners; PTGFR activation has negligible effects on AT1R-based conformational biosensors. (AT1R = angiotensin II receptor, type 1; PTGFR = prostaglandin F2alpha receptor; GNAQ = GTP-binding protein G[q] subunit alpha)

  8. GNAQ and GNA11 mutations occur frequently in mucosal melanoma and may be a prognostic factor for MM. Our data implicate that GNAQ/11 may be potential targets for targeted therapy of mucosal melanoma.

  9. Results found that GNAQ was highly expressed in gastric cancer (GC) patient samples and suggest that GNAQ plays a critical role in regulating GC cell growth and survival via canonical oncogenic signaling pathways including MAPK (显示 MAPK1 抗体) and p53 (显示 TP53 抗体).

  10. These findings suggest that Galphaq/11 participates in the sensing/transducing of shear stress independently of GPCR activation in ECs.

Pig (Porcine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. The Galphas (显示 GNAS 抗体) and Galphaq peptides adopt different orientations in beta2-AR and V1AR (显示 AVPR1A 抗体), respectively. The beta2-AR/Galphas (显示 GNAS 抗体) peptide interface is dominated by electrostatic interactions, whereas the V1AR (显示 AVPR1A 抗体)/Galphaq peptide interactions are predominantly hydrophobic.

  2. The phylogenetic trees reveal that porcine Gnaq, is evolutionarily close to the human homolog.

Cow (Bovine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. atomic structure of GRK2 (显示 ADRBK1 抗体) in complex with Galphaq and Gbetagamma, in which the activated Galpha (显示 SUCLG1 抗体) subunit of Gq is fully dissociated from Gbetagamma and dramatically reoriented from its position in the inactive Galphabetagamma heterotrimer [g alphaq]

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), Q Polypeptide (GNAQ) interaction partners

  1. Galphaq regulates the development of rheumatoid arthritis by modulating Th1 (显示 HAND1 抗体) differentiation

  2. Fluid shear stress acts on the Galphaq-ERK5 (显示 MAPK7 抗体) signaling pathway to upregulate Cyclin B1 (显示 CCNB1 抗体) and CDK1 (显示 CDK1 抗体) expression, thereby resulting in MC3T3-E1 cell proliferation.

  3. activation of the Gq-membrane-associated estrogen receptors rapidly stimulates hypothalamic paraventricular nucleus CRH (显示 CRH 抗体) neurons by suppressing the M-current and potentiating glutamatergic neurotransmission

  4. cell-penetrating peptides should effectively inhibit active Galphaq in cells and that these and genetically encoded sequences may find application as molecular probes, drug leads, and biosensors to monitor the spatiotemporal activation of Galphaq in cells.

  5. The Galphas (显示 GNAS 抗体) and Galphaq peptides adopt different orientations in beta2-AR and V1AR (显示 AVPR1A 抗体), respectively. The beta2-AR/Galphas (显示 GNAS 抗体) peptide interface is dominated by electrostatic interactions, whereas the V1AR (显示 AVPR1A 抗体)/Galphaq peptide interactions are predominantly hydrophobic.

  6. the results have identified 138 and 150 ovarian genes that are up-regulated or down-regulated, respectively, at the end of gestation in a Galphaq/11-dependent fashion.

  7. The betaARKrgs peptide, but not endogenous GRK2 (显示 ADRBK1 抗体), interacted with Galpha(q) and interfered with signaling through this G protein. These data support the development of GRK2 (显示 ADRBK1 抗体)-based therapeutic approaches to prevent hypertrophy and heart failure.

  8. Galphaq/Galpha11 signaling pathways play a pivotal role in gene activity patterns during cardiac remodeling.

  9. Developmental AHR activation by pollutants, and other exogenous ligands, increases the likelihood that Gnaq knockout mice will develop autoimmune diseases later in life.

  10. demonstrate that the ability of an MC4R (显示 MC4R 抗体) agonist delivered to PVN to inhibit food intake is lost in mice lacking G(q/11)alpha in the paraventricular nucleus of the hypothalamus but not in animals deficient for G(s)alpha

GNAQ 抗原简介

Antigen Summary

This locus encodes a guanine nucleotide-binding protein. The encoded protein, an alpha subunit in the Gq class, couples a seven-transmembrane domain receptor to activation of phospolipase C-beta. Mutations at this locus have been associated with problems in platelet activation and aggregation. A related pseudogene exists on chromosome 2.

Alternative names and synonyms associated with GNAQ

  • guanine nucleotide binding protein (G protein), q polypeptide (gnaq) 抗体
  • guanine nucleotide binding protein (G protein), q polypeptide (GNAQ) 抗体
  • guanine nucleotide binding protein (G protein), q polypeptide (Gnaq) 抗体
  • guanine nucleotide binding protein (G protein), q polypeptide (gnaq-b) 抗体
  • guanine nucleotide binding protein, alpha q polypeptide (Gnaq) 抗体
  • 1110005L02Rik 抗体
  • 6230401I02Rik 抗体
  • AA408290 抗体
  • AW060788 抗体
  • CMC1 抗体
  • Dsk1 抗体
  • Dsk10 抗体
  • g-alpha-q 抗体
  • Galphaq 抗体
  • gaq 抗体
  • Gnaq 抗体
  • gnaqb 抗体
  • Gq 抗体
  • GqI 抗体
  • si:ch73-270f14.2 抗体
  • SWS 抗体

Protein level used designations for GNAQ

Galpha q , gnaqa , guanine nucleotide-binding protein G(q) subunit alpha , guanine nucleotide-binding protein alpha-q , G alpha q , guanine nucleotide binding protein alpha q subunit , guanine nucleotide binding protein, alpha q polypeptide , guanine nucleotide regulatory protein G alpha q , heterotrimeric guanine nucleotide-binding protein alpha q subunit , guanine nucleotide-binding protein G(q) alpha subunit

GENE ID SPECIES
570108 Danio rerio
2776 Homo sapiens
403928 Canis lupus familiaris
81666 Rattus norvegicus
427262 Gallus gallus
654405 Sus scrofa
536654 Bos taurus
399261 Xenopus laevis
14682 Mus musculus
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