CSF2 蛋白 (CSF2)产品概述

Full name:
Colony Stimulating Factor 2 (Granulocyte-Macrophage) 蛋白 (CSF2)
在www.antibodies-online.cn可供143 Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) 蛋白的16不同的供货商。 再加上,我们可以发CSF2 抗体 (287)CSF2 试剂盒 (103)和数多这个蛋白质的别的产品。 总共546 CSF2产品已列进来了。
CSF, CSF2, Csfgm, Gm-csf, Gmcsf, MGI-IGM
列出全部蛋白 基因 基因ID UniProt
CSF2 1437 P04141
CSF2 12981 P01587
CSF2 116630 P48750


按照种类CSF2 蛋白 (CSF2)


引用最多的CSF2 蛋白

  1. Human CSF2 Protein expressed in Escherichia coli (E. coli) - ABIN2017902 : Djalilian, Caicedo, Lessan, Grami, Le, Spellman, Pambuccian, Hall, Low, Ondrey: Efficacy of an osmotic pump delivered, GM-CSF-based tumor vaccine in the treatment of upper aerodigestive squamous cell carcinoma in rats. in Cancer immunology, immunotherapy : CII 2007 (PubMed)
    Show all 8 references for 2017902

  2. Rat (Rattus) CSF2 Protein expressed in Human Cells - ABIN2009045 : Ebner, Bandion, Binder, de Martin, Schmid: GMCSF activates NF-kappaB via direct interaction of the GMCSF receptor with IkappaB kinase beta. in Blood 2003 (PubMed)
    Show all 5 references for 2009045

  3. Human CSF2 Protein expressed in Yeast - ABIN2001920 : Volmar, Ait-Ghezala, Frieling, Paris, Mullan: The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta) production. in Cytokine 2008 (PubMed)
    Show all 5 references for 2001920

  4. Human CSF2 Protein expressed in Human Cells - ABIN2001912 : Frolova, Dolganov, Mazo, Smirnov, Copeland, Stewart, OBrien, Dean: Linkage mapping of the human CSF2 and IL3 genes. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 5 references for 2001912

  5. Mouse (Murine) CSF2 Protein expressed in Human Cells - ABIN2008546 : Hamilton: GM-CSF in inflammation and autoimmunity. in Trends in immunology 2002 (PubMed)
    Show all 5 references for 2008546

  6. Human CSF2 Protein expressed in Escherichia coli (E. coli) - ABIN934919 : Spatz, Eibl, Hink, Wolf, Fischer, Mayr, Schernthaner, Eibl: Impaired primary immune response in type-1 diabetes. Functional impairment at the level of APCs and T-cells. in Cellular immunology 2003 (PubMed)


Horse (Equine) Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. TRAF6 (显示 TRAF6 蛋白) is also required for GM-CSF-induced ubiquitination and activation of Akt (显示 AKT1 蛋白).

Human Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. Obesity alters the lung neutrophil infiltration to enhance breast cancer metastasis through IL5 (显示 IL5 蛋白) and GM-CSF.

  2. Data suggest that the methylotrophic yeast Pichia pastoris is an effective recombinant host for heterologous granulocyte-macrophage colony-stimulating factor (rhGM-CSF) production.

  3. Letter: Knockdown of either filaggrin (显示 FLG 蛋白) or loricrin (显示 LOR 蛋白) increases the productions of interleukin (IL)-1alpha, IL-8 (显示 IL8 蛋白), IL-18 (显示 IL18 蛋白) and granulocyte macrophage colony-stimulating factor in stratified human keratinocytes.

  4. Impaired RASGRF1 (显示 RASGRF1 蛋白)/ERK (显示 EPHB2 蛋白)-mediated GM-CSF response characterizes CARD9 (显示 CARD9 蛋白) deficiency in French-Canadians.

  5. Honokiol could possess potential anti-inflammatory effects and inhibits TNF-alpha (显示 TNF 蛋白)-induced IL-1beta (显示 IL1B 蛋白), GM-CSF and IL-8 (显示 IL8 蛋白) production in PBMCs from rheumatoid arthritis patients.

  6. The canonical NFkappaB (显示 NFKB1 蛋白) signaling in fibroblasts, but not in tumor cells, was shown to be responsible for the induced and constitutive CSF2 expression.

  7. GM-CSF primes IL-13 (显示 IL13 蛋白) production by macrophages via PAR-2 (显示 F2RL1 蛋白).

  8. analysis of an IL2RA (显示 IL2RA 蛋白) polymorphism that controls GM-CSF production in human TH cells

  9. NFKBIZ (显示 NFKBIZ 蛋白) gene knockdown in bronchial epithelial cells suppresses the release of IL-1b (显示 IL1B 蛋白)-induced IL-6 (显示 IL6 蛋白) and GMCSF.

  10. CFH (显示 CFH 蛋白) Y402H polymorphism is associated with elevated vitreal GM-CSF and choroidal macrophages in the postmortem human eye.

Cow (Bovine) Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. These results demonstrated that bovine colonic cells seem capable to respond to E. bovis merozoite I infection by the upregulation of CXCL10 (显示 CXCL10 蛋白) and GM-CSF gene transcription.

  2. Data suggest exposure to maternal CSF2 from D5-D7 of development is fundamentally different for female/male blastocysts with respect to embryo elongation, characteristics of transcriptome/methylome, and endometrial interferon tau secretion at D15 (显示 MRPL16 蛋白).

  3. The increase in calving rate caused by CSF2 treatment involves, in part, more extensive development of extraembryonic membranes and capacity of the conceptus to secrete IFNT2 at day 15 of pregnancy.

  4. immunolocalization studies confirmed the presence of granulocyte-macrophage colony stimulating factor(GM-CSF) in the germ cell line in bovine and human testes and addition of GM-CSF enhances several parameters of sperm motility

  5. the conceptus, through its secretion of IFN-tau, stimulates maternal epithelial expression of COX-2 (显示 PTGS2 蛋白) and GM-CSF during the peri (显示 PLIN1 蛋白)-attachment period in the cow.

  6. CSF2 affect embryonic development and enhance embryo competence for posttransfer survival.

Mouse (Murine) Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. Obesity alters the lung neutrophil infiltration to enhance breast cancer metastasis through IL5 (显示 IL5 蛋白) and GM-CSF.

  2. GM-CSF is required for the normal balance of leukocyte subsets, including granulocytes, B cells, and naive vs. effector T cells. There was an approximately 3-fold increase in the percentages of granulocytes in Csf2-/- PBMCs. The presence of maximal experimental autoimmune encephalomyelitis in the complete absence of GM-CSF revealed that GM-CSF is not an obligate effector molecule in all forms of EAE.

  3. chemerin (显示 RARRES2 蛋白) inhibited nuclear factor-kappaB activation and the expression of granulocyte-macrophage colony-stimulating factor (GM-CSF) and interleukin-2 (显示 IL2 蛋白) (IL-6 (显示 IL6 蛋白)) by tumor cells and tumor-associated endothelial cell, respectively, via its receptors, and consequently, MDSC induction was impaired, leading to restoration of antitumor T-cell response and decreased tumor angiogenesis.

  4. These findings describe a novel role for GM-CSF as an essential initiating cytokine in cardiac inflammation.

  5. Data reviewed establish that any damage to brain tissue tends to cause an increase in G-CSF (显示 CSF3 蛋白) and/or GM-CSF (G(M)-CSF (显示 CSF1R 蛋白)) synthesized by the brain. Glioblastoma cells themselves also synthesize G(M)-CSF (显示 CSF1R 蛋白). G(M)-CSF (显示 CSF1R 蛋白) synthesized by brain due to damage by a growing tumor and by the tumor itself stimulates bone marrow to shift hematopoiesis toward granulocytic lineages away from lymphocytic lineages.

  6. Evi1 (显示 MECOM 蛋白)(+)DA-3 cells modified to express an intracellular form of GM-CSF, acquired growth factor independence and transplantability and caused an overt leukemia in syngeneic hosts, without increasing serum GM-CSF levels.

  7. IL-23 (显示 IL23A 蛋白)-induced GM-CSF mediates the pathogenicity of CD4 (显示 CD4 蛋白)(+) T cells in experimental autoimmune myocarditis.

  8. GM-CSF accelerated the G1/S phase transition in EPCs by upregulating the expression of cyclins D1 and E.

  9. Proteomic Analysis Reveals Distinct Metabolic Differences Between Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) and Macrophage Colony Stimulating Factor (M-CSF (显示 CSF1R 蛋白)) Grown Macrophages Derived from Murine Bone Marrow Cells

  10. host RNF13 (显示 RNF13 蛋白) affects the concentration of GM-CSF in tumor-bearing lungs

Pig (Porcine) Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. CSF2 stimulates proliferation of trophectoderm cells by activation of the PI3K-and ERK1/2 MAPK (显示 MAPK1 蛋白)-dependent MTOR (显示 FRAP1 蛋白) signal transduction cascades.

Goat Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2) interaction partners

  1. Data indicate that differentially expressed IL-17 (显示 IL17A 蛋白), IL-22 (显示 IL22 蛋白), and IL-23 (显示 IL23A 蛋白) levels are associated with K-ras (显示 HRAS 蛋白) in a stage-specific fashion along colorectal cancer progression and an association was established between mutant K-ras (显示 HRAS 蛋白) and GM-CSF and IFN-gamma (显示 IFNG 蛋白).



The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.

Alternative names and synonyms associated with CSF2

  • granulocyte-macrophage colony-stimulating-factor (GM-CSF)
  • colony stimulating factor 2 (granulocyte-macrophage) (CSF2)
  • granulocyte-macrophage colony-stimulating factor (GM-CSF)
  • colony stimulating factor 2 (granulocyte-macrophage) (Csf2)
  • granulocyte-macrophage colony stimulating factor (GM-CSF)
  • CSF 蛋白
  • CSF2 蛋白
  • Csfgm 蛋白
  • Gm-csf 蛋白
  • Gmcsf 蛋白
  • MGI-IGM 蛋白

Protein level used designations for CSF2

granulocyte-macrophage colony-stimulating factor , colony stimulating factor 2 (granulocyte-macrophage) , CSF , molgramostin , sargramostim , colony-stimulating factor , granulocyte-macrophage colony stimulating factor 2 , put. GM-CSF , GM-CSF , granulate-macrophage stimulating factor , granulocyte-macrophage stimulation factor

100033981 Equus caballus
100126743 Papio anubis
100137216 Papio anubis
471627 Pan troglodytes
1437 Homo sapiens
281095 Bos taurus
12981 Mus musculus
116630 Rattus norvegicus
443400 Ovis aries
403923 Canis lupus familiaris
397208 Sus scrofa
416325 Gallus gallus
100135508 Cavia porcellus
493805 Felis catus
574371 Macaca mulatta
100861208 Capra hircus
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