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兔 IgG isotype control (Biotin)

ABIN964370 产品详细信息, 供应商: Log in to see
亚型
宿主

218
210
208
172
162
130
114
94
93
92
91
76
59
52
44
42
27
25
24
23
22
11
8
6
3
3
1
抗体类型
Native
标记
Biotin
206
169
168
166
157
108
58
58
48
45
20
13
12
12
11
9
9
6
6
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
3
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
应用范围
Isotype Control (IsoC), ELISA, Western Blotting (WB)
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亚型 IgG
片段 Fc fragment
产品特性 Concentration Definition: by UV absorbance at 280 nm
背景 Immunoglobulin G is the most abundant antibody isotype found in the circulation. IgG molecules are synthesized and secreted by plasma B cells. IgG antibodies are large molecules of about 150 kDa composed of four peptide chains. It contains two identical class γ heavy chains of about 50 kDa and two identical light chains of about 25 kDa, thus a tetrameric quaternary structure. An antibody digested by papain yields three fragments, two Fab fragments and one Fc fragment An antibody digested by pepsin yields two fragments: a F(ab')2 fragment and a pFc' fragment. The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. Rabbit IgG F(c) is ideal for investigators involved in serum protein component research.

Synonyms: Rabbit IgG Fragment, Rabbit IgG Fc, Rabbit Conjugate
分子量 150 kDa
基因ID 100343867
研究领域 Immunology, Secondary Antibodies
应用备注 Rabbit IgG F(c) fragment can be utilized as a control or standard reagent in Western Blotting and ELISA experiments. Speific conditions should be optimized by user.
限制 仅限研究用
状态 Lyophilized
溶解方式 Restore with deionized water (or equivalent)
浓度 1.0 mg/mL
缓冲液 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
储存液 Sodium azide
注意事项 WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
注意事项 Aliquot to Avoid repeated freezing and thawing.
储存条件 4 °C