NEW: 请通过本地经销商订购 4A Biotech Co.,Ltd.

小鼠 IgG 同型对照

ABIN1098804 产品详细信息, 供应商: Log in to see
亚型
宿主
小鼠
217
206
204
169
160
127
112
93
88
88
88
73
56
50
43
42
27
25
24
22
21
11
8
3
3
2
1
抗体类型
Recombinant
应用范围
Isotype Control (IsoC), SDS-PAGE (SDS)
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

亚型 IgG
纯化方法 purified by chromatography
纯度 > 90 % by SDS-PAGE
背景 Immunoglobulin G (IgG) are antibody molecules. Each IgG is composed of four peptide chains (two heavy chains gamma and two light chains). Each IgG has two antigen binding sites. IgG antibodies are involved in predominantly the secondary immune response. The presence of specific IgG, in general, corresponds to maturation of the antibody response. It plays an important role in Antibody-dependent cell-mediated cytotoxicity (ADCC) and Intracellular antibody-mediated proteolysis, in which it binds to TRIM21 (the receptor with greatest affinity to IgG in humans) in order to direct marked virions to the proteasome in the cytosol. Recombinant mouse IgG protein, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography techniques.
Synonyms: Immunoglobulin heavy chain constant region gamma 2a, Immunoglobulin G
分子量 26.6 kDa (236aa)
研究领域 Immunology, Secondary Antibodies
应用备注 Each Investigator should determine their own optimal working dilution for specific applications.
说明

Concentration (detection method): 0.5 mg/mL (determined by Bradford assay)

限制 仅限研究用
状态 Liquid
浓度 0.5 mg/mL
缓冲液 20 mM Tris-HCl buffer (pH 8.0)
注意事项 Avoid repeated freezing and thawing cycles.
储存条件 4 °C
厂商提供的图像
 image for 小鼠 IgG 同型对照 (ABIN1098804) Mouse IgG isotype control
背景 Brüggemann, Teale, Clark, Bindon, Waldmann: "A matched set of rat/mouse chimeric antibodies. Identification and biological properties of rat H chain constant regions mu, gamma 1, gamma 2a, gamma 2b, gamma 2c, epsilon, and alpha." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 142, Issue 9, pp. 3145-50, 1989 (PubMed).