PPARGC1A (PPARGC1A) ELISA试剂盒产品概述

Full name:
Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha ELISA试剂盒 (PPARGC1A)
在www.antibodies-online.cn可供2 Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) ELISA试剂盒的2不同的供货商。 总共2 PPARGC1A产品已列进来了。
别名:
A830037N07Rik, AVPGC-1ALPHA, ENSMUSG00000079510, Gm11133, LEM6, PGC-1, PGC-1(alpha), Pgc-1alpha, PGC-1v, PGC1, PGC1A, Pgco1, Ppargc1, PPARGC1A
list all ELISA KIts 基因 基因ID UniProt
PPARGC1A 19017 O70343
PPARGC1A 10891 Q9UBK2
大鼠 PPARGC1A PPARGC1A 83516 Q9QYK2

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PPARGC1A (PPARGC1A) ELISA试剂盒 by Reactivity

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适于 PPARGC1A 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) interaction partners

  1. Destabilization of PGC1a is attributable to decreased p38 MAPK (显示 MAPK14 ELISA试剂盒) activation via diminished CaMKII (显示 CAMK2G ELISA试剂盒) signaling. Thus, we elucidate a pathway downstream of Ca(2 (显示 CA2 ELISA试剂盒)+)-mediated CaMKII (显示 CAMK2G ELISA试剂盒) activation that is dysfunctional in C3KO(Capn3 (显示 CAPN3 ELISA试剂盒) knock-out mice ) mice, leading to reduced transcription of genes involved in muscle adaptation

  2. lncBATE10 can decoy Celf1 (显示 CELF1 ELISA试剂盒) from Pgc1alpha, thereby protecting Pgc1alpha mRNA from repression by Celf1 (显示 CELF1 ELISA试剂盒)

  3. Since the R6/2 mice represent a 'truncated' huntingtin (Htt (显示 HTT ELISA试剂盒)) mouse model of Huntington's disease (HD), we tested the efficacy of bezafibrate in a 'full-length' Htt (显示 HTT ELISA试剂盒) mouse model, the BACHD mice. Bezafibrate treatment restored the impaired PPARg (显示 PPARG ELISA试剂盒), PPARd (显示 PPARD ELISA试剂盒), PGC (显示 PGC ELISA试剂盒)-1a signaling pathway, enhanced mitochondrial biogenesis and improved antioxidant defense in the striatum of BACHD mice

  4. this study shows that PGC-1alpha overexpression improves metabolism in virus-specific CD8 (显示 CD8A ELISA试剂盒)+ T cells generated during acute infection

  5. This is the first study to dissect the mechanism by which the antiadipogenic and anti-inflammatory lipid, Epoxyeicosatrienoic acid, induces the PGC-1alpha signaling cascade and reprograms the adipocyte phenotype by regulating mitochondrial function and HO-1 (显示 HMOX1 ELISA试剂盒) expression.

  6. The accelerated conversion of T4 to T3 within myocytes mediates part of the PGC (显示 PGC ELISA试剂盒)-1a induction by treadmill exercise and its downstream effects on mitochondrial function

  7. Study demonstrates a novel role for peroxisome proliferator-activated receptor gamma (显示 PPARG ELISA试剂盒) coactivator-1alpha (PGC-1alpha) in nucleus accumbens (NAc (显示 NLRP1 ELISA试剂盒)) in cocaine action. PGC-1alpha is enhanced in NAc (显示 NLRP1 ELISA试剂盒) dopamine D1-medium spiny neurons, specifically after cocaine exposure. These data are consistent with increased active methylation and early growth response 3 (显示 EGR3 ELISA试剂盒) binding at the PGC-1alpha promoter.

  8. These data reveal a new role for muscle PGC-1alpha in regulating the physiological adaptation to long-term LCHF diet administration.

  9. These results demonstrate a central role of skeletal muscle PGC-1alpha in the transcriptional regulation of systemic ketolytic capacity.

  10. Our results indicate that prolonged Htr2b (显示 HTR2B ELISA试剂盒) activation in murine beta-cells decreases glucose-stimulated insulin (显示 INS ELISA试剂盒) secretion and mitochondrial activity by mechanisms likely dependent on enhanced PGC1a/PPARygexpression.

Pig (Porcine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) interaction partners

  1. Study investigated the molecular basis of such effects focusing on a commonly studied polymorphism in pig Pgc1alpha, which changes a cysteine at position 430 (WT) of the protein to a serine (C430S); found that differential O-GlcNAcylation of Pgc1alpha regulates PCK1 (显示 PCK1 ELISA试剂盒) activity and this molecular mechanism could explain at least in part the epistatic interaction between both genes.

  2. Transcription of the gene was detected in adipose, muscle, kidney, liver, brain, heart and adrenal gland tissues, which is in agreement with the function of PPARGC1A in adaptive thermogenesis.

  3. The purpose of this study was to screen for new single nucleotide polymorphisms in exon 8 of the porcine PPARGC1A gene and to test their possible association with production traits.

  4. impact of PPARGC1A on energy and lipid metabolism in vivo, through several downstream target genes

  5. The *2690T>C and *2864T>C polymorphisms in PPARGC1A can be used as genetic markers for selection toward improved meat quality.

  6. The c.-2894G>A polymorphism in the 5' upstream region of the porcine PPARGC1A gene can be used as a meaningful molecular marker for simultaneous improvement of lean meat production and quality traits.

  7. PPARGC1A may play a key role in down-regulating lipid deposition, and the SNPs with differential genotype distribution among three breeds may be related to gene expression and fat deposition.

  8. Polymorphisms in PPARGC1A and CAPNS1 (显示 CAPNS1 ELISA试剂盒) genes may affect meat quality traits.

Human Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) interaction partners

  1. Low-intensity endurance cycling exercise performed with blood flow restriction failed to increase PGC-1alpha expression to that commonly observed with endurance exercise. Isoform-specific postexercise increases in the alpha4 isoform along with Hif-1alpha and VEGF mRNA expression following higher intensity endurance exercise without blood flow restriction.

  2. These results highlight the combined effects of Parkin (显示 PARK2 ELISA试剂盒) and PGC-1alpha in the maintenance of mitochondrial homeostasis in dopaminergic neurons. These two factors synergistically control the quality and function of mitochondria, which is important for the survival of neurons in Parkinson's disease.

  3. PPARGC1A rs4235308 has no significant association with ALS.

  4. Supplementation of omega-3 fatty acids in combination with vitamin E may have beneficial effects on coronary artery disease patients by increasing gene expression of SIRT1 (显示 SIRT1 ELISA试剂盒) and PGC1alpha and improving oxidative stress and inflammation in these patients.

  5. Results delineate a cross talk between a central pathway controlling metabolic regulation and cell adhesion, and identify PGC-1alpha as a molecular link between these two major cellular networks.

  6. Haplotype-based interaction between the PPARGC1A and UCP1 (显示 UCP1 ELISA试剂盒) genes is associated with impaired fasting glucose (IFG (显示 IFNG ELISA试剂盒)) or type 2 diabetes mellitus (T2DM) among the residents of Henan province, China. Individuals with the haplotype AAG (显示 MPG ELISA试剂盒) (PPARGC1A gene) and CTCG (UCP1 (显示 UCP1 ELISA试剂盒) gene) have increased susceptibility to IFG (显示 IFNG ELISA试剂盒) or T2DM, while those with haplotype AAG (显示 MPG ELISA试剂盒) (PPARGC1A gene) and CTCA (UCP1 (显示 UCP1 ELISA试剂盒) gene) have a lower risk of IFG (显示 IFNG ELISA试剂盒) or T2DM.

  7. The miR (显示 MLXIP ELISA试剂盒)-130b-3p down-regulates PGC-1alpha expression in placental trophoblasts, and inhibition of miR (显示 MLXIP ELISA试剂盒)-130b-3p appears to improve mitochondrial biogenesis signaling and protect placental trophoblast cells from oxidative stress.

  8. the RAR-related orphan receptor-a (显示 RORA ELISA试剂盒) gene (RORA (显示 RORA ELISA试剂盒)) and the Peroxisome Proliferator-Activated Receptor Gamma (显示 PPARG ELISA试剂盒), Coactivator 1 Alpha gene (PPARGC1A or PGC-1alpha) were significantly associated with the Li response. Our results suggest genetic associations between Li response and these two close biological partners: PPARGC1A and RORA (显示 RORA ELISA试剂盒) involved in circadian rhythms and bioenergetics processes in Li response

  9. Schizophrenia involves a disruption in PGC-1alpha and/or NRF-1 (显示 NFE2L1 ELISA试剂盒)-associated transcriptional programs in the cortex.

  10. In molecular dynamics simulations, PGC1alpha induced correlated atomic motion throughout the entire LRH-1 (显示 NR5A2 ELISA试剂盒) activation function surface.

Cow (Bovine) Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 alpha (PPARGC1A) interaction partners

  1. PPARGC1A single nucleotide polymorphisms associated with milk fatty acids in a Chinese Holstein cattle.

  2. The PPARGC1A synonymous mutation c.396G>A significantly associated with body weight and average daily gain in Nanyang cattle at the adult age.

  3. PPARGC1A genotypes had a significant effect on lengths of calving interval and calving to conception interval, and the T allele was demonstrated to have an unfavourable effect on these traits.

  4. NO/protein kinase (显示 CDK7 ELISA试剂盒) G (PKG (显示 PRKG1 ELISA试剂盒))-dependent downregulation of PGC-1 alpha and the ROS (显示 ROS1 ELISA试剂盒) detoxification system in endothelial cells are mediated by the PI3K/Akt (显示 AKT1 ELISA试剂盒) signaling

  5. The effects of dietary fat components on the expression of PPAR-gamma (显示 PPARG ELISA试剂盒) AND PPAR-gamma coactivator 1 in cultured bovine preadipocytes are reported.

  6. genetic analysis of bovine PPARGC1A

  7. PPARGC1A was associated with a significant increase in milk protein (显示 CSN2 ELISA试剂盒) percentage in contrast to association results previously reported for the German Holstein population

PPARGC1A 抗原简介

Antigen Summary

The protein encoded by this gene is a transcriptional coactivator that regulates the genes involved in energy metabolism. This protein interacts with PPARgamma, which permits the interaction of this protein with multiple transcription factors. This protein can interact with, and regulate the activities of, cAMP response element binding protein (CREB) and nuclear respiratory factors (NRFs). It provides a direct link between external physiological stimuli and the regulation of mitochondrial biogenesis, and is a major factor that regulates muscle fiber type determination. This protein may be also involved in controlling blood pressure, regulating cellular cholesterol homoeostasis, and the development of obesity.

Alternative names and synonyms associated with PPARGC1A

  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PPARGC1A) Elisa Kit
  • peroxisome proliferative activated receptor, gamma, coactivator 1 alpha (Ppargc1a) Elisa Kit
  • peroxisome proliferator activated receptor gamma, coactivator 1 alpha (PPARGC-1) Elisa Kit
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (Ppargc1a) Elisa Kit
  • peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (ppargc1a) Elisa Kit
  • A830037N07Rik Elisa Kit
  • AVPGC-1ALPHA Elisa Kit
  • ENSMUSG00000079510 Elisa Kit
  • Gm11133 Elisa Kit
  • LEM6 Elisa Kit
  • PGC-1 Elisa Kit
  • PGC-1(alpha) Elisa Kit
  • Pgc-1alpha Elisa Kit
  • PGC-1v Elisa Kit
  • PGC1 Elisa Kit
  • PGC1A Elisa Kit
  • Pgco1 Elisa Kit
  • Ppargc1 Elisa Kit
  • PPARGC1A Elisa Kit

Protein level used designations for PPARGC1A

peroxisome proliferator-activated receptor gamma, coactivator 1 alpha , PPAR-gamma coactivator , peroxisome proliferator activated receptor gamma coactivator-1 , PGC-1-alpha , PPAR Gamma Coactivator-1 , PPAR gamma coactivator variant form , PPAR-gamma coactivator 1-alpha , PPARGC-1-alpha , Pgc-1alphaa , peroxisome proliferator-activated receptor gamma coactivator 1-alpha , L-PGC-1alpha , ligand effect modulator-6 , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4 , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5 , peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT , peroxisome proliferative activated receptor, gamma, coactivator 1 , peroxisome proliferator activated receptor gamma coactivator 1 alpha , PGC-1alpha , peroxisome proliferative activated receptor gamma coactivator 1 , peroxisome proliferative activated receptor, gamma, coactivator 1 alpha , proliferator-activated receptor gamma coactivator 1 alpha , peroxisome proliferative activated receptor, gamma, coactivator 1, alpha , peroxisome-proliferator-activated receptor-gamma co-activator-1

GENE ID SPECIES
443270 Ovis aries
19017 Mus musculus
397013 Sus scrofa
10891 Homo sapiens
479127 Canis lupus familiaris
338446 Bos taurus
83516 Rattus norvegicus
100462892 Xenopus laevis
422815 Gallus gallus
100349219 Oryctolagus cuniculus
100721512 Cavia porcellus
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