K(lysine) Acetyltransferase 5 (KAT5) ELISA试剂盒产品概述

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K(lysine) Acetyltransferase 5 ELISA试剂盒 (KAT5)
在www.antibodies-online.cn可供4 K(lysine) Acetyltransferase 5 (KAT5) ELISA试剂盒的2不同的供货商。 再加上,我们可以发K(lysine) Acetyltransferase 5 抗体 (168)K(lysine) Acetyltransferase 5 蛋白 (14)和数多这个蛋白质的别的产品。 总共202 K(lysine) Acetyltransferase 5产品已列进来了。
别名:
6121, AI839539, CG6121, CPLA2, DmEG0007.7, Dmel/TIP60, Dmel\\CG6121, Dmel\\TIP60, dmHAG405, dTip60, EG0007.7, EG:EG0007.7, ESA1, Htatip, Htatip1, im:6908768, PLIP, TIP, Tip55, Tip60, wu:fb55b08, ZC2HC5, zgc:110752

K(lysine) Acetyltransferase 5 (KAT5) ELISA试剂盒 by Reactivity

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Fruit Fly (Drosophila melanogaster) K(lysine) Acetyltransferase 5 (KAT5) interaction partners

  1. Our results implicate Tip60 as a critical mediator of EE-induced benefits, and provide broad insights into synergistic behavioral and epigenetic based therapeutic approaches for treatment of cognitive disorder.

  2. compromising Tip60 histone acetyltransferase (显示 HAT ELISA试剂盒) activity in the CySC (显示 CST3 ELISA试剂盒) lineage recapitulates loss-of-function phenotypes of E(Pc), suggesting that Tip60 and E(Pc) act together, consistent with published biochemical data.

  3. Heat Shock Factor recruits the dTip60 complex to the hsp70 loci in cells treated with salicylate, which triggers chromatin remodeling at these loci without transcription activation.

  4. Excess Tip60 exerts a neuroprotective role in axonal transport and functional locomotion defects in an animal model of Alzheimer's disease.

  5. a novel mechanism for Tip60 mediated sleep-wake regulation via control of axonal growth and PDF levels within the small ventrolateral neurons-encompassing neural network

  6. a functional interaction between Tip60 and APP (显示 APP ELISA试剂盒) in mediating nervous system development and apoptotic neuronal cell death

  7. The role of Tip60 HAT (显示 HAT ELISA试剂盒) activity in transcriptional control during multicellular development in vivo, was investigated.

  8. Ubiquitous dTip60 knock-down in flies was lethal, whereas knock-down in the wing imaginal disk led to developmental defects.

  9. demonstrated that the dTip60 chromatin-remodeling complex acetylates nucleosomal phospho-H2Av (显示 H2AFV ELISA试剂盒) and exchanges it with an unmodified H2Av (显示 H2AFV ELISA试剂盒); both the histone acetyltransferase (显示 HAT ELISA试剂盒) dTip60 and the atpase (显示 DNAH8 ELISA试剂盒) Domino/p400 catalyze the exchange of phospho-H2Av (显示 H2AFV ELISA试剂盒)

  10. TIP60 complex can promote the generation of silent chromatin.

Human K(lysine) Acetyltransferase 5 (KAT5) interaction partners

  1. Methylation of RUVBL1 by the arginine methyltransferase PRMT5 (显示 PRMT5 ELISA试剂盒) is required for homologous recombination-mediated double-strand break repair by promoting TIP60-mediated histone H4K16 acetylation.

  2. TIP60 complex regulates bivalent chromatin recognition/modification by 53BP1 (显示 TP53BP1 ELISA试剂盒) through direct H4K20me binding and H2AK15 acetylation.

  3. Studies suggest that lysine (K) acetyltransferase inhibitors (KATi (显示 CCBL1 ELISA试剂盒)) are important for providing personalized therapies.

  4. Thus Tip60 interacts with RNR and NME3 to provide site-specific synthesis of dNTP for facilitating DNA repair in serum-deprived cells which contain low levels of dNTPs.

  5. TIP60 acted downstream of UHRF2 (显示 UHRF2 ELISA试剂盒) to regulate H3K9ac and H3K14ac expression.

  6. Data provide evidence that the acetylation of H2AX (显示 H2AFX ELISA试剂盒) at Lys5 (显示 AASDHPPT ELISA试剂盒) by TIP60 is required for the (ADPribosyl) ation activity and the dynamic binding of PARP-1 (显示 PARP1 ELISA试剂盒) to chromatin after the induction of DNA damage.

  7. Synthetic lethality screening identifies TIP60-dependent radiation sensitivity in the absence of BAF180 (显示 PBRM1 ELISA试剂盒).

  8. E1A (显示 BCKDHA ELISA试剂盒) 243R promotes association of MYC (显示 MYC ELISA试剂盒)/MAX with the NuA4/Tip60 complex, implicating the importance of the MYC (显示 MYC ELISA试剂盒)/NuA4 pathway in cellular transformation by both MYC (显示 MYC ELISA试剂盒) and E1A (显示 BCKDHA ELISA试剂盒).

  9. UV irradiation enhanced the binding of ATF3 (显示 ATF3 ELISA试剂盒) to Tip60, knockdown of ATF3 (显示 ATF3 ELISA试剂盒) expression decreased Tip60 stability, thereby impairing Tip60 induction by UV irradiation.

  10. KAT5 is significantly elevated in malignant pleural mesothelioma

Mouse (Murine) K(lysine) Acetyltransferase 5 (KAT5) interaction partners

  1. Results report that EPC1 (显示 EPC1 ELISA试剂盒) and TIP60 are co-expressed in male germ cells. Genetic ablation of either Epc1 (显示 EPC1 ELISA试剂盒) or Tip60 disrupts hyperacetylation and impairs histone replacement, in turn causing aberrant spermatid development.

  2. these results identify a new compaction pathway of mammalian pericentric heterochromatin relying on Tip60 that might be dependent on BRD2 (显示 BRD2 ELISA试剂盒) recruitment by H4K12 acetylation.

  3. The expression of putative SOX4 target genes during myoblast differentiation is specifically regulated by the molecular switching of the co-activator KAT5 and the co-repressor HDAC1 on SOX4 transcriptional activation.

  4. TIP60 K327 acetylation allows TIP60 to switch binding partners. conditional knockout in Treg cells results in autoimmune disease.

  5. Allele compensation in tip60+/- mice rescues white adipose tissue function in vivo.

  6. Tip60 hyperacetylates histone H4 in Ras-transformed cells.Tip60 coordinates histone acetylation at both local and global levels to facilitate Ras-induced transformation.

  7. RGS6 (显示 RGS6 ELISA试剂盒) suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 (显示 DNMT1 ELISA试剂盒) degradation and promoting apoptosis

  8. Early adipogenesis is regulated through USP7 (显示 USP7 ELISA试剂盒)-mediated deubiquitination of the histone acetyltransferase TIP60.

  9. SLX2 interacts with synaptonemal complex central element protein 2 (SYCE2 (显示 SYCE2 ELISA试剂盒)) and histone acetyltransferase TIP60.

  10. these results suggest that Tip60 binds with Pax6 (显示 PAX6 ELISA试剂盒) and that this physical interaction leads to the full-transcriptional activation of Pax6 (显示 PAX6 ELISA试剂盒) during retina development.

K(lysine) Acetyltransferase 5 (KAT5) 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants.

Alternative names and synonyms associated with K(lysine) Acetyltransferase 5 (KAT5)

  • zgc:92510 (zgc:92510) Elisa Kit
  • K(lysine) acetyltransferase 5 (LOC100340634) Elisa Kit
  • CG6121 gene product from transcript CG6121-RA (Tip60) Elisa Kit
  • histone acetyltransferase Tip60 (Tip60) Elisa Kit
  • tip60 (AaeL_AAEL014072) Elisa Kit
  • tip60 (Smp_053140) Elisa Kit
  • HIV-1 tat interactive protein, homolog (human) (htatip) Elisa Kit
  • K(lysine) acetyltransferase 5 (KAT5) Elisa Kit
  • K(lysine) acetyltransferase 5 (Kat5) Elisa Kit
  • 6121 Elisa Kit
  • AI839539 Elisa Kit
  • CG6121 Elisa Kit
  • CPLA2 Elisa Kit
  • DmEG0007.7 Elisa Kit
  • Dmel/TIP60 Elisa Kit
  • Dmel\\CG6121 Elisa Kit
  • Dmel\\TIP60 Elisa Kit
  • dmHAG405 Elisa Kit
  • dTip60 Elisa Kit
  • EG0007.7 Elisa Kit
  • EG:EG0007.7 Elisa Kit
  • ESA1 Elisa Kit
  • Htatip Elisa Kit
  • Htatip1 Elisa Kit
  • im:6908768 Elisa Kit
  • PLIP Elisa Kit
  • TIP Elisa Kit
  • Tip55 Elisa Kit
  • Tip60 Elisa Kit
  • wu:fb55b08 Elisa Kit
  • ZC2HC5 Elisa Kit
  • zgc:110752 Elisa Kit

Protein level used designations for KAT5

K(lysine) acetyltransferase 5 , CG6121-PA , CG6121-PB , CG6121-PC , Tat-interactive protein , Tip60-PA , Tip60-PB , Tip60-PC , histone acetyltransferase Tip60 , tip60 , HIV-1 tat interactive protein , 60 kDa Tat-interactive protein , HIV-1 Tat interactive protein, 60kDa , K-acetyltransferase 5 , Tat interacting protein, 60kDa , cPLA(2)-interacting protein , cPLA2 interacting protein , histone acetyltransferase HTATIP , histone acetyltransferase KAT5 , HIV-1 tat interactive protein 1, 60 kDa homolog , HIV-1 tat interactive protein 1, homolog , Tat-interactive protein-60 , lysine acetyltransferase 5 , HIV-1 Tat interacting protein, 60kDa , HIV-1 Tat interactive protein 60 kD , HIV-1 Tat interactive protein, 60 kD , HIV-1 tat interactive protein, homolog , Histone acetyltransferase HTATIP

GENE ID SPECIES
436638 Danio rerio
100340634 Oryctolagus cuniculus
31362 Drosophila melanogaster
413101 Apis mellifera
5579231 Aedes aegypti
8344228 Schistosoma mansoni
503731 Danio rerio
10524 Homo sapiens
81601 Mus musculus
483728 Canis lupus familiaris
505619 Bos taurus
192218 Rattus norvegicus
451329 Pan troglodytes
100174410 Pongo abelii
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