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ABIN412271 产品详细信息, 供应商: Log in to see
Functional Studies (Func), Cell Culture (CC), Blocking Reagent (BR), Inhibition Assay (InhA)
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原理 A GSK-3 inhibitor
产品特性 A potent, selective, reversible and ATP-competitive inhibitor of GSK-3alpha/beta (IC50 = 5 nM). Under a feeder-free condition, BIO maintains embryonic stem cells (hESCs) in the undifferentiated state.
纯度 ≥ 98 %
Chemical Name (2Z, 3E)-6'-Bromo-3-(hydroxyimino)-[2,3'-biindolinylidene]-2'-one
Formula C₁₆H₁₀BrN₃O₂
Permeability Cell-permeable
Solubility DMSO (10 mg/ml) or EtOH (0.5 mg/ml)
分子量 356.17 g/mol
CAS-编号 667463-62-9
限制 仅限研究用
状态 Solid
注意事项 Protect from air and light
储存条件 -20 °C
有效期 24 months
 image for BIO (ABIN412271) BIO
有引用在: Zhou, Zhang, Wu, Ghai, Field: "Phosphorylation of the cytoskeletal protein CAP1 controls its association with cofilin and actin." in: Journal of cell science, Vol. 127, Issue 23, pp. 5052-65, 2014 (PubMed).