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Agitoxin-2

BR, InhA 168147-41-9
产品编号 ABIN2566170
发货至: 中国
  • 应用范围
    Blocking Reagent (BR), Inhibition Assay (InhA)
    原理
    Agitoxin-2 is a potent blocker of Kv1.1 and Kv1.3 channels
    序列
    AA sequence: Gly-Val-Pro-Ile-Asn-Val-Ser-Cys8-Thr-Gly -Ser-Pro-Gln-Cys14-Ile-Lys-Pro-Cys18-Lys-Asp- Ala-Gly-Met-Arg-Phe-Gly-Lys-Cys28-Met-Asn -Arg-Lys-Cys33-His-Cys35-Thr-Pro-Lys-OH Disulfide bonds: Cys8-Cys28, Cys14-Cys33, Cys18-Cys35
    特异性
    Agitoxin-2 is a potent blocker of Kv1.1 and Kv1.3 channels
    产品特性
    Agitoxin-2 is a potent and selective blocker of the Shaker type voltage-gated Kv1.3 and Kv1.1 channels. Agitoxin-2 inhibits Kv1.3 with an IC50 value of around 200 pM and Kv1.1 with an IC50 value of around 140 pM. This peptide toxin was originally isolated from the venom of the Israeli scorpion L. quinquestriatus hebraeus.
    Formula
    C169H278N54O48S8
    Solubility
    water and saline buffer
  • 限制
    仅限研究用
  • 状态
    Powder
    储存条件
    -20 °C
  • 分子量
    4090.89 Da
    CAS-编号
    168147-41-9
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