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Human TTR ELISA Kit for Sandwich ELISA - ABIN414684
Li, Zheng, Huang, Lin, Zhao, Liao, Zhao, Lin, Gu: Screening disease-associated proteins from sera of patients with rheumatoid arthritis: a comparative proteomic study. in Chinese medical journal 2010
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Human TTR ELISA Kit for Sandwich ELISA - ABIN2685836
Hamilton, Benson: Transthyretin: a review from a structural perspective. in Cellular and molecular life sciences : CMLS 2001
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Human TTR ELISA Kit for Competition ELISA - ABIN366135
Apori, Brozynski, El-Sayed, Herr: Microfluidic validation of diagnostic protein markers for spontaneous cerebrospinal fluid rhinorrhea. in Journal of proteome research 2013
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Rat (Rattus) TTR ELISA Kit for Sandwich ELISA - ABIN1874306
Kinouchi, Matsuyama, Kitagawa, Kamimori: Surface plasmon resonance assay of inhibition by pharmaceuticals for thyroxine hormone binging to transport proteins. in Analytical biochemistry 2015
TTR induced apoptosis of retinal microvascular endothelial cells in an environment that simulated hypoxia.
Data suggest that transthyretin exhibits site-specific solvation of the indole ring of tryptophans W41 and W79; these studies involved incorporation of tryptophan labeled with fluorine at 5 or 6 positions (5-fluorotryptophan/5FW or 6-fluorotryptophan/6FW) into recombinant TTR; replacement of fluorine at 5-position of a tryptophan with one at adjacent 6-position emphasizes delicate balance of stability in TTR tetramer.
This study shows that highly destabilized, aggregation-prone TTR variants are secreted as both native tetramers and non-native conformations that accumulate as high-molecular-weight oligomers.
The role of transthyretin in normal pregnancy is reviewed.
the role of H88 and the hydrogen bond network in the stability of TTR
we identify a somatic mosaicism, in several subjects affected by familial amyloidotic polyneuropathy, involving the dominant c.325G>C mutation of the TTR gene
The role of Transthyretin in the regulation of Ubc9 (显示 UBE2I ELISA试剂盒) SUMOylation
Gene sequencing revealed a phenylalanine-->isoleucine mutation in the 33rd position of exon 2 of TTR in 1 patient of 1 pedigree, confirming the diagnosis of FAP. Two patients subsequently were found to have sensorimotor autonomic neuropathy, whereas 2 others had subclinical autonomic dysfunction.
TTR V30M aggregates and autophagy impairment are associated with Transthyretin amyloidoses .
In Afro-Caribbean patients living in London, ATTR V122I is an underappreciated cause of heart failure, and cardiomyopathy is often misattributed to hypertension.
New insights into ghrelin (显示 GHRL ELISA试剂盒) cell physiology, and given the known functions of RBP4 (显示 RBP4 ELISA试剂盒) and TTR, support an emerging role for the ghrelin (显示 GHRL ELISA试剂盒) cell in blood glucose handling and metabolism.
Transthyretin (TTR) deposition in the peripheral nervous system is the hallmark of familial amyloidotic polyneuropathy (FAP (显示 FAP ELISA试剂盒)).
TTR mediated transport of thyroxine represents a survival mechanism necessary for the myogenic program.
provide evidence of a new role of Transthyretin as a transcription inducer of insulin (显示 INS ELISA试剂盒)-like growth factor receptor (显示 RYK ELISA试剂盒) I in central nervous system, unveiling a new role in neuroprotection
data also indicate that it is unlikely that the behaviors seen in Ttr(-/-) mice are related to its function
Native transthyretin inhibits all preeclampsia-like features in the humanized mouse model.
Transthyretin silencing (TTRkd) significantly reduced myogenin (显示 MYOG ELISA试剂盒) expression.
Amyloid fibrils formed by a mutant form of TTR, A25T, activate microglia, leading to the secretion of tumor necrosis factor-alpha (TNF-alpha (显示 TNF ELISA试剂盒)), interleukin-6 (IL-6 (显示 IL6 ELISA试剂盒)) and nitric oxide.
Hsf-1 (显示 HSF1 ELISA试剂盒) affects podocyte markers NPHS1 (显示 NPHS1 ELISA试剂盒), NPHS2 and WT1 (显示 WT1 ELISA试剂盒) in a transgenic mouse model of TTRVal30Met-related amyloidosis.
Fibroblasts endocytose and degrade transthyretin aggregates in transthyretin-related amyloidosis.
The rank order potency of the chemicals tested for the displacement of [125I]TIP from TTR was TIP > ioxynil > pentachlorophenol, T4, and retinoic acid > tetrabromobisphenol A, diethylstilbestrol, and T3.
This study suggested closer links between the release of haptoglobin (显示 HP ELISA试剂盒), Pig-MAP and monocytes compared to the release of AGP (显示 USMG5 ELISA试剂盒), SAA (显示 SAA1 ELISA试剂盒) and transthyretin.
Study determined the genomic structure of the Xenopus laevis TTR gene including 5'-flanking regions, and examined TTR expression patterns in several tissues; coding regions of xTTR gene was separated into 4 exons by 3 introns and these numbers were in agreement with those determined for the human, mouse, and rat genes
This gene encodes transthyretin, one of the three prealbumins including alpha-1-antitrypsin, transthyretin and orosomucoid. Transthyretin is a carrier protein\; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported\; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic. The diseases caused by mutations include amyloidotic polyneuropathy, euthyroid hyperthyroxinaemia, amyloidotic vitreous opacities, cardiomyopathy, oculoleptomeningeal amyloidosis, meningocerebrovascular amyloidosis, carpal tunnel syndrome, etc.
, transthyretin (prealbumin, amyloidosis type I)
, transthyretin (prealbumin, amyloidosis type 1)
, carpal tunnel syndrome 1
, prealbumin, amyloidosis type I
, thyroxine-binding prealbumin