V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) ELISA试剂盒产品概述

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V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) ELISA试剂盒 (MAFA)
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别名:
2F1-Ag, hMafA, L-MAF, MAFA, MAFA-L, mafl, RGD1562627, RIPE3b1, SMaf1
list all ELISA KIts 基因 基因ID UniProt
小鼠 MAFA MAFA 50928 O88713
大鼠 MAFA MAFA 58975 Q64335
 MAFA MAFA 389692 Q8NHW3

显示所有的同义词

适于 V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) 相互作用对的更多 ELISA 试剂盒

Mouse (Murine) V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) interaction partners

  1. Treg cell accumulation in intestinal tumours from APC (显示 APC ELISA试剂盒)(min/+) mice was exclusively due to the increase in KLRG1 (显示 KLRG1 ELISA试剂盒)(+) GATA3 (显示 GATA3 ELISA试剂盒)(+) Treg cells.

  2. Although absence of KLRG1 (显示 KLRG1 ELISA试剂盒) is not enough to increase intestinal Treg cells in KLRG1 (显示 KLRG1 ELISA试剂盒) knockout mice, KLRG1 (显示 KLRG1 ELISA试剂盒) ligation reduces T-cell receptor signals and the competitive fitness of individual Treg cells in the intestine.

  3. Mafa was found to both potentiate the ability of Pdx1 (显示 PDX1 ELISA试剂盒) to induce beta-cell formation from Ngn3 (显示 NEUROG3 ELISA试剂盒)-positive endocrine precursors and enable Pdx1 (显示 PDX1 ELISA试剂盒) to produce beta-cells from alpha-cells.

  4. Ly6C, 4-1BB (显示 TNFRSF9 ELISA试剂盒), and KLRG1 (显示 KLRG1 ELISA试剂盒) have roles in the activation of lamina propria lymphocytes in the small intestine in a mouse model of Crohn's disease

  5. MAFA controls autonomic nervous system-mediated insulin secretion by activating the transcription of nicotinic (ChrnB2 and ChrnB4) receptor genes, which is impaired in type 2 diabetes.

  6. These findings demonstrate that regulation of monoamine levels by Mao (显示 MAO ELISA试剂盒) activity in beta cells is pivotal for physiological insulin (显示 INS ELISA试剂盒) secretion and that loss of MaoB (显示 MAOB ELISA试剂盒) expression may contribute to the beta cell dysfunction in type 2 diabetes.

  7. is necessary for the maintenance of normal insulin (显示 INS ELISA试剂盒) levels even in embryos.

  8. endogenous small-Maf (显示 MAF ELISA试剂盒) factors negatively regulate beta-cell function by competing for MafA binding, and thus, the inhibition of small-Maf (显示 MAF ELISA试剂盒) activity can improve beta-cell function

  9. Data, including data from studies using transgenic/knockout mice, confirm the expression of Mafa and Mafb (显示 MAFB ELISA试剂盒) is specific to insulin (显示 INS ELISA试剂盒)-secreting cells of the pancreas.

  10. These results suggest that MafA regulates the postnatal proliferation of beta-cells via prolactin (显示 PRL ELISA试剂盒) signaling.

Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) interaction partners

  1. Pdx1 (显示 PDX1 ELISA试剂盒) and MafA (显示 KLRG1 ELISA试剂盒) play crucial roles in the pancreas and maintain mature beta-cell function. Our results showed that the expression of Pdx1 (显示 PDX1 ELISA试剂盒) and MafA (显示 KLRG1 ELISA试剂盒) were significantly upregulated after a sleeve gastrectomy for morbid obesity.

  2. MAFA controls autonomic nervous system-mediated insulin secretion by activating the transcription of nicotinic (ChrnB2 and ChrnB4) receptor genes, which is impaired in patients with type 2 diabetes.

  3. These findings demonstrate that regulation of monoamine levels by Mao (显示 MAO ELISA试剂盒) activity in beta cells is pivotal for physiological insulin (显示 INS ELISA试剂盒) secretion and that loss of MaoB (显示 MAOB ELISA试剂盒) expression may contribute to the beta cell dysfunction in type 2 diabetes.

  4. MAFA (显示 KLRG1 ELISA试剂盒), MAFB (显示 MAFB ELISA试剂盒), NKX6.1 (显示 NKX6-1 ELISA试剂盒), and PDX1 (显示 PDX1 ELISA试剂盒) activity provides a gauge of islet beta cell function, with loss of MAFA (显示 KLRG1 ELISA试剂盒) (and/or MAFB (显示 MAFB ELISA试剂盒)) representing an early indicator of beta cell inactivity

  5. Loss of MAFA (显示 KLRG1 ELISA试剂盒) expression is associated with insulinoma (显示 RPS15 ELISA试剂盒).

  6. MAFA (显示 KLRG1 ELISA试剂盒) nuclear expression in pancreatic alpha and beta cells, and the percentage of alpha cells expressing PAX4 (显示 PAX4 ELISA试剂盒) are altered in patients with type 2 diabetes.

  7. under oxidative and nonoxidative conditions p38 MAPK (显示 MAPK14 ELISA试剂盒) directly binds to MafA (显示 KLRG1 ELISA试剂盒) and triggers MafA (显示 KLRG1 ELISA试剂盒) degradation via ubiquitin proteasomal pathway.

  8. Beta cell nuclear MafA (显示 KLRG1 ELISA试剂盒) is markedly decreased in humans with type 2 diabetes, which may contribute to impaired beta cell dysfunction.

  9. Combined transfection of the three transcriptional factors, PDX-1 (显示 PDX1 ELISA试剂盒), NeuroD1 (显示 NEUROD1 ELISA试剂盒), and MafA (显示 KLRG1 ELISA试剂盒), causes differentiation of bone marrow mesenchymal stem cells into insulin (显示 INS ELISA试剂盒)-producing cells

  10. Data suggest that MafA (显示 KLRG1 ELISA试剂盒) plays a novel role in the reprogramming of stem cells into pancreatic beta-progenitors, promotes the islet-like characteristics of PDMSCs, as well as functionally regulation of blood glucose levels in transplanted grafts.

V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA) 抗原简介

Antigen Summary

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS\; MIM 176730) (Olbrot et al., 2002

Alternative names and synonyms associated with V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A (Avian) (MAFA)

  • killer cell lectin-like receptor subfamily G, member 1 (Klrg1) Elisa Kit
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (mafa) Elisa Kit
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene A (Mafa) Elisa Kit
  • v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) Elisa Kit
  • v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian) (Mafa) Elisa Kit
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (MAFA) Elisa Kit
  • v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) (mafa) Elisa Kit
  • 2F1-Ag Elisa Kit
  • hMafA Elisa Kit
  • L-MAF Elisa Kit
  • MAFA Elisa Kit
  • MAFA-L Elisa Kit
  • mafl Elisa Kit
  • RGD1562627 Elisa Kit
  • RIPE3b1 Elisa Kit
  • SMaf1 Elisa Kit

Protein level used designations for MAFA

killer cell lectin-like receptor subfamily G member 1 , mast cell function-associated antigen 2F1 , mast cell function-associated antigen , v-maf musculoaponeurotic fibrosarcoma oncogene homolog A , Transcription factor MafA , leucine zipper transcription factor , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A , pancreatic beta-cell-specific transcriptional activator , transcription factor MafA , transcription factor RIPE3b1 , Mafa homolog , V-maf musculoaponeurotic fibrosarcoma oncogene homolog A , bZIP transcription factor L-Maf , lens-specific Maf , somite Maf1 , v-maf musculoaponeurotic fibrosarcoma oncogene family, protein L

GENE ID SPECIES
50928 Mus musculus
58975 Rattus norvegicus
613050 Xenopus (Silurana) tropicalis
366949 Rattus norvegicus
389692 Homo sapiens
378435 Mus musculus
395881 Gallus gallus
100000492 Danio rerio
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