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Human OSTN ELISA Kit for Sandwich ELISA - ABIN423109
Miriyala, Thippakorn, Chaiswing, Xu, Noel, Tovmasyan, Batinic-Haberle, Vander Kooi, Chi, Latif, Panchatcharam, Prachayasittikul, Butterfield, Vore, Moscow, St Clair: Novel role of 4-hydroxy-2-nonenal in AIFm2-mediated mitochondrial stress signaling. in Free radical biology & medicine 2016
Show all 2 Pubmed References
findings suggest that, in response to sensory input, OSTN regulates features of neuronal structure and function that are unique to primates
The circulating concentration of musclin was significantly increased in type 2 diabetes mellitus patients. Results suggest that musclin has a strong relationship with insulin (显示 INS ELISA试剂盒) resistance in type 2 diabetes mellitus.
osteocrin represents a novel, unique vitamin D-regulated bone-specific protein that appears to act as a soluble osteoblast regulator
Foxo1 (显示 FOXO1 ELISA试剂盒) downregulates musclin mRNA expression both in vitro and in vivo, which should explain insulin (显示 INS ELISA试剂盒)-mediated upregulation of this gene in muscle cells.
Ostn is a naturally occurring ligand of the NPR-C (显示 NPR3 ELISA试剂盒) clearance receptor and may act to locally modulate the actions of the natriuretic system in bone by blocking the clearance action of NPR-C (显示 NPR3 ELISA试剂盒), thus locally elevating levels of C-type natriuretic peptide (显示 NPPC ELISA试剂盒).
Data show that musclin (Ostn) production is stimulated by Ca2 (显示 CA2 ELISA试剂盒)+-dependent proto-oncogene (显示 RAB1A ELISA试剂盒) protein c (显示 PROC ELISA试剂盒)-Akt (Akt (显示 AKT1 ELISA试剂盒)) phosphorylation.
findings suggest that palmitate increases musclin gene expression via the activation of the PERK signaling pathway in C2C12 myotubes
Musclin expression level is tightly regulated by nutritional changes and its physiological role could be linked to glucose metabolism
we detected 2 SNPs, A85C and T335C, that were located on the 3rd exon and the 3 untranslated regions of the bovine Osteocrin gene, respectively, using 413 Qinchuan cattle DNA samples.
involved in regulation of bone formation and mineralization