电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

Low Density Lipoprotein Receptor 抗体

(Low Density Lipoprotein Receptor (LDLR))
The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010].
LDLR 抗体  (C-Term) LDLR 抗体  (C-Term) LDLR 抗体 (C-Term) (ABIN7268296)

KO Validated LDLR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

LDLR 抗体  (AA 22-150) LDLR 抗体  (AA 22-150) LDLR 抗体 (AA 22-150) (ABIN5542334)

LDLR 适用: 人 WB, ELISA, FACS, IHC, ICC 宿主: 小鼠 Monoclonal 1B10H10 unconjugated

LDLR 抗体  (AA 781-860) LDLR 抗体  (AA 781-860) LDLR 抗体 (AA 781-860) (ABIN672111)

LDLR 适用: 人, 小鼠, 大鼠, Hamster, 植物 WB, ELISA, FACS, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

Low Density Lipoprotein Receptor 抗体 by Grade

Find Low Density Lipoprotein Receptor 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor 抗体 by 适用

Find Low Density Lipoprotein Receptor 抗体 for a variety of species such as anti-Human Low Density Lipoprotein Receptor, anti-Mouse Low Density Lipoprotein Receptor, anti-Rat Low Density Lipoprotein Receptor. The species listed below are among those available. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor 抗体 by 应用范围

Find Low Density Lipoprotein Receptor 抗体 validated for a specific application such as WB, FACS, ELISA, IHC. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor 抗体 by 抗体来源

Find Low Density Lipoprotein Receptor 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor 抗体 by 抗原表位

Find Low Density Lipoprotein Receptor 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor 抗体 by 克隆形成能力

Find available monoclonal or polyclonal Low Density Lipoprotein Receptor 抗体. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor 抗体 by 克隆

Find Low Density Lipoprotein Receptor 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

Low Density Lipoprotein Receptor 抗体 by 标记

Find Low Density Lipoprotein Receptor 抗体 with a specific conjugate such as Biotin, FITC, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular Low Density Lipoprotein Receptor 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
Cat. No. ABIN7268296
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC
Validations
  • (5)
Cat. No. ABIN5542334
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Hamster, Human, Mouse, Plant, Rat
Application WB, ELISA, FACS, IF (p), IHC (p)
Validations
  • (5)
  • (3)
Cat. No. ABIN672111
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS, IHC, IF
Validations
  • (4)
Cat. No. ABIN7127599
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC
Validations
  • (4)
Cat. No. ABIN7249770
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7432991
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7440485
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN561655
Quantity 100 μg
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, ICC
Validations
  • (4)
Cat. No. ABIN5013888
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IHC, ICC, IHC (p)
Validations
  • (2)
Cat. No. ABIN1909537
Quantity 1 each
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, FACS
Validations
  • (3)
Cat. No. ABIN3031637
Quantity 0.4 mL
Datasheet Datasheet
Reactivity Human
Application FACS
Validations
  • (1)
Cat. No. ABIN6992499
Quantity 50 tests
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7158563
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, ICC, IF
Validations
  • (1)
Cat. No. ABIN6262943
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN561654
Quantity 50 μL
Datasheet Datasheet

Latest Publications for our Low Density Lipoprotein Receptor 抗体

Moessinger, Nilsson, Muhl, Zeitelhofer, Heller Sahlgren, Skogsberg, Eriksson: "VEGF-B signaling impairs endothelial glucose transcytosis by decreasing membrane cholesterol content." in: EMBO reports, Vol. 21, Issue 7, pp. e49343, (2020) (PubMed).

Lebeau, Platko, Al-Hashimi, Byun, Lhoták, Holzapfel, Gyulay, Igdoura, Cool, Trigatti, Seidah, Austin: "Loss-of-function PCSK9 mutants evade the unfolded protein response sensor GRP78 and fail to induce endoplasmic reticulum stress when retained." in: The Journal of biological chemistry, Vol. 293, Issue 19, pp. 7329-7343, (2019) (PubMed).

Khoshnejad, Patel, Wojtak, Kudchodkar, Humeau, Lyssenko, Rader, Muthumani, Weiner: "Development of Novel DNA-Encoded PCSK9 Monoclonal Antibodies as Lipid-Lowering Therapeutics." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 27, Issue 1, pp. 188-199, (2019) (PubMed).

Sharma, Gupta, Dahiya, Kumar, Vaiphei, Agnihotri: "Clinical relevance of cholesterol homeostasis genes in colorectal cancer." in: Biochimica et biophysica acta. Molecular and cell biology of lipids, Vol. 1864, Issue 10, pp. 1314-1327, (2019) (PubMed).

Silva, Lütjohann, Hamid, Velasquez, Kerner, Larrazabal, Failing, Hermosilla, Taubert: "Besnoitia besnoiti infection alters both endogenous cholesterol de novo synthesis and exogenous LDL uptake in host endothelial cells." in: Scientific reports, Vol. 9, Issue 1, pp. 6650, (2019) (PubMed).

Xu, Xu, Xu, Yin, Zhang: "Global inactivation of carboxylesterase 1 (Ces1/Ces1g) protects against atherosclerosis in Ldlr-/-mice." in: Scientific reports, Vol. 7, Issue 1, pp. 17845, (2018) (PubMed).

Fischer, Albers, Krott, Hoffzimmer, Heine, Schmale, Scheja, Gordts, Heeren: "The adaptor protein PID1 regulates receptor-dependent endocytosis of postprandial triglyceride-rich lipoproteins." in: Molecular metabolism, Vol. 16, pp. 88-99, (2018) (PubMed).

Riad, Zeng, Weng, Winters, Xu, Makvandi, Metz, Carlin, Mach: "Sigma-2 Receptor/TMEM97 and PGRMC-1 Increase the Rate of Internalization of LDL by LDL Receptor through the Formation of a Ternary Complex." in: Scientific reports, Vol. 8, Issue 1, pp. 16845, (2018) (PubMed).

Saxena, Kaur, Chandra: "Differential Response of B Cells to an Immunogen, a Mitogen and a Chemical Carcinogen in a Mouse Model System" in: Asian Pacific journal of cancer prevention : APJCP, Vol. 19, Issue 1, pp. 81-90, (2018) (PubMed).

Sirois, Chrétien, Mbikay: "Comparing expression and activity of PCSK9 in SPRET/EiJ and C57BL/6J mouse strains shows lack of correlation with plasma cholesterol." in: Molecular genetics and metabolism reports, Vol. 10, pp. 11-17, (2017) (PubMed).

Aliases for Low Density Lipoprotein Receptor 抗体

low density lipoprotein receptor (LDLR) 抗体
low density lipoprotein receptor (Ldlr) 抗体
low density lipoprotein receptor a (ldlra) 抗体
low density lipoprotein receptor S homeolog (ldlr.S) 抗体
low density lipoprotein receptor L homeolog (ldlr.L) 抗体
FH 抗体
FHC 抗体
fhc 抗体
Hlb301 抗体
LDLA 抗体
LDLCQ2 抗体
ldlcq2 抗体
ldlr 抗体
ldlr-a 抗体
ldlr-b 抗体
ldlr2-a 抗体
LDLRA 抗体
LDL receptor-2 抗体
LDL receptor 1 抗体
You are here:
客服