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抗Human DISP2 抗体:
抗Mouse (Murine) DISP2 抗体:
抗Rat (Rattus) DISP2 抗体:
dispatched plays a role in hedgehog (显示 SHH 抗体) body patterning, as demonstrated in transgenic mice
The pattern of cellular proliferation and differentiation that leads to normal development of embryonic structures often depends upon the localized production of secreted protein signals. Cells surrounding the source of a particular signal respond in a graded manner according to the effective concentration of the signal, and this response produces the pattern of cell types constituting the mature structure. A segment-polarity gene known as dispatched has been identified in Drosophila and its protein product is required for normal Hedgehog (Hh) signaling. This gene is one of two human homologs of Drosophila dispatched.
dispatched homolog 2 (Drosophila)
, dispatched B
, protein dispatched homolog 2