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HAS2 抗体

(Hyaluronan Synthase 2 (HAS2))
Hyaluronan or hyaluronic acid (HA) is a high molecular weight unbranched polysaccharide synthesized by a wide variety of organisms from bacteria to mammals, and is a constituent of the extracellular matrix. It consists of alternating glucuronic acid and N-acetylglucosamine residues that are linked by beta-1-3 and beta-1-4 glycosidic bonds. HA is synthesized by membrane-bound synthase at the inner surface of the plasma membrane, and the chains are extruded through pore-like structures into the extracellular space. It serves a variety of functions, including space filling, lubrication of joints, and provision of a matrix through which cells can migrate. HA is actively produced during wound healing and tissue repair to provide a framework for ingrowth of blood vessels and fibroblasts. Changes in the serum concentration of HA are associated with inflammatory and degenerative arthropathies such as rheumatoid arthritis. In addition, the interaction of HA with the leukocyte receptor CD44 is important in tissue-specific homing by leukocytes, and overexpression of HA receptors has been correlated with tumor metastasis. HAS2 is a member of the newly identified vertebrate gene family encoding putative hyaluronan synthases, and its amino acid sequence shows significant homology to glycosaminoglycan synthetase (DG42) from Xenopus laevis, and human and murine hyaluronan synthase 1. [provided by RefSeq, Jul 2008].
HAS2 抗体  (AA 67-170) HAS2 抗体  (AA 67-170) HAS2 抗体 (AA 67-170) (ABIN1098124)

HAS2 适用: 人 ELISA, WB, IHC, ICC 宿主: 小鼠 Monoclonal 4-00E-07 unconjugated

HAS2 抗体  (AA 138-166) HAS2 抗体  (AA 138-166) HAS2 抗体 (AA 138-166) (ABIN651874)

HAS2 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22492 unconjugated

HAS2 抗体 HAS2 抗体 HAS2 抗体 (ABIN1386495)

HAS2 适用: 人, 小鼠, 大鼠 WB, IF (p), IHC (p) 宿主: 兔 Polyclonal unconjugated

HAS2 抗体 by 适用

Find HAS2 抗体 for a variety of species such as anti-Human HAS2, anti-Mouse HAS2, anti-Rat HAS2. The species listed below are among those available. Click on a link to go to the corresponding products.

HAS2 抗体 by 应用范围

Find HAS2 抗体 validated for a specific application such as WB, ELISA, IHC, IF (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

HAS2 抗体 by 抗体来源

Find HAS2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

HAS2 抗体 by 抗原表位

Find HAS2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

HAS2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal HAS2 抗体. Click on a link to go to the corresponding products.

HAS2 抗体 by 克隆

Find HAS2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

HAS2 抗体 by 标记

Find HAS2 抗体 with a specific conjugate such as FITC, Biotin, HRP. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular HAS2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, WB, IHC, ICC
Validations
  • (2)
  • (5)
Cat. No. ABIN1098124
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, FACS, IHC (p)
Validations
  • (2)
  • (4)
Cat. No. ABIN651874
Quantity 200 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p), IHC (p)
Validations
  • (1)
Cat. No. ABIN1386495
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IF
Validations
  • (1)
Cat. No. ABIN7155956
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN6141613
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, WB, IHC, IHC (p), IF
Validations
  • (1)
Cat. No. ABIN1804680
Quantity 50 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
Cat. No. ABIN1390393
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
Cat. No. ABIN7091236
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p)
Validations
Cat. No. ABIN1390389
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p)
Validations
Cat. No. ABIN1390390
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p)
Validations
Cat. No. ABIN1390391
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p)
Validations
Cat. No. ABIN2814142
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p)
Validations
Cat. No. ABIN1390392
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p)
Validations
Cat. No. ABIN1408282
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IF (p)
Validations
Cat. No. ABIN1408283
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our HAS2 抗体

Wang, Zhou, Wang, Liu, Chen, Jiang, Luo, Stupack, Luo: "Role of Hyaluronan and Glucose on 4-Methylumbelliferone-inhibited Cell Proliferation in Breast Carcinoma Cells." in: Anticancer research, Vol. 35, Issue 9, pp. 4799-805, (2016) (PubMed).

Lien, Lee, Jeng, Lin, Lu, Yao: "Differential expression of hyaluronan synthase 2 in breast carcinoma and its biological significance." in: Histopathology, Vol. 65, Issue 3, pp. 328-39, (2015) (PubMed).

Kobayashi, Banno, Shimizu, Ueki, Tsuji, Masuda, Kisu, Nomura, Tominaga, Nagano, Saya, Aoki: "Gene expression profile of a newly established choriocarcinoma cell line, iC3-1, compared to existing choriocarcinoma cell lines and normal placenta." in: Placenta, Vol. 34, Issue 2, pp. 110-8, (2013) (PubMed).

Okuda, Kobayashi, Xia, Watabe, Pai, Hirota, Xing, Liu, Pandey, Fukuda, Modur, Ghosh, Wilber, Watabe: "Hyaluronan synthase HAS2 promotes tumor progression in bone by stimulating the interaction of breast cancer stem-like cells with macrophages and stromal cells." in: Cancer research, Vol. 72, Issue 2, pp. 537-47, (2012) (PubMed).

Jokela, Makkonen, Oikari, Kärnä, Koli, Hart, Tammi, Carlberg, Tammi: "Cellular content of UDP-N-acetylhexosamines controls hyaluronan synthase 2 expression and correlates with O-linked N-acetylglucosamine modification of transcription factors YY1 and SP1." in: The Journal of biological chemistry, Vol. 286, Issue 38, pp. 33632-40, (2011) (PubMed).

Aliases for HAS2 抗体

hyaluronan synthase 2 (has2) 抗体
hyaluronan synthase 2 (HAS2) 抗体
hyaluronan synthase 2 (Has2) 抗体
hyaluronan synthase 2 (SHAS2) 抗体
hyaluronan synthase 2 S homeolog (has2.S) 抗体
DG42 抗体
Has2 抗体
XHas2 抗体
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