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Mouse (Murine) CD44 ELISA Kit for Sandwich ELISA - ABIN457122
Campo, Avenoso, DAscola, Prestipino, Scuruchi, Nastasi, Calatroni, Campo: Inhibition of hyaluronan synthesis reduced inflammatory response in mouse synovial fibroblasts subjected to collagen-induced arthritis. in Archives of biochemistry and biophysics 2012
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Human CD44 ELISA Kit for Sandwich ELISA - ABIN2859264
Li, Chu, Gao, Li: Apoptotic mechanism of MCF-7 breast cells in vivo and in vitro induced by photodynamic therapy with C-phycocyanin. in Acta biochimica et biophysica Sinica 2009
pERK1/2 is a regulator of CD44 expression, and increased CD44 expression leads to a pro-sclerotic and migratory parietal epithelial cell phenotype in focal segmental glomerulosclerosis.
MET signaling regulates intestinal homeostasis and regeneration, as well as adenoma formation. These activities of MET are promoted by the stem cell CD44 isoform CD44v4-10.
study demonstrates that CD44 plays a critical role in the regulation of experimental autoimmune encephalomyelitis through alterations in the gut microbiome profile and short-chain fatty acid production
CD44 variant isoform 9 emerges in response to injury and contributes to the regeneration of the gastric epithelium.
OA/GPNMB acts through ERK (显示 EPHB2 ELISA试剂盒) and AKT (显示 AKT1 ELISA试剂盒) signaling pathways in mesenchymal stem cells via CD44
These findings support the usefulness of the conditional Cd44 allele in unraveling essential physiological and pathological functions of CD44 isoforms.
CD44 role in the atrophic epidermis
CD44(high) type II cells likely represent a type II cell subpopulation important for constitutive regulation of alveolar homeostasis.
CD44V6 is part of a positive-feedback loop with TGFbeta1 (显示 TGFB1 ELISA试剂盒)/TGFbetaRI signaling that acts to increase NOX4 (显示 NOX4 ELISA试剂盒)/ROS (显示 ROS1 ELISA试剂盒) production, which is required for myofibroblast differentiation, myofibroblast differentiation, myofibroblast extracellular matrix production, myofibroblast invasion, and myofibroblast contractility.
HAS2 (显示 HAS2 ELISA试剂盒)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (显示 MAPK3 ELISA试剂盒)/EGR1 (显示 EGR1 ELISA试剂盒) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (显示 TGFB1 ELISA试剂盒)-stimulated CD44V6/ERK (显示 EPHB2 ELISA试剂盒)/EGR1 (显示 EGR1 ELISA试剂盒) signaling.
Increased CD44s protein and posttranslational modification of CD44 with polylactosamine on macrophages from stage III could be involved in the cleaning up apoptotic granulosa cells
CD44 has a key role in oocyte maturation but not in cumulus expansion.
This study demonstrates that the CD14 (显示 CD14 ELISA试剂盒)-negative isolation yields an enhanced cell population SFB (显示 CEBPB ELISA试剂盒) that is more potent than MSCP (显示 SLC25A37 ELISA试剂盒) as a cell source for cartilage tissue engineering.
CD44 is expressed in the cumulus-oocyte complexes during cumulus expansion. The interaction between hyaluronan and CD44 is closely related to gap junctional communication of the cumulus-oocyte complexes during meiotic resumption.
suggest that upregulation of NG2/CSPG4 (显示 MCSP ELISA试剂盒) rather than changes in CD44 or Ki-67 (显示 MKI67 ELISA试剂盒) expression is associated with low overall survival in glioblastoma multiforme patients, supporting NG2/CSPG4 (显示 MCSP ELISA试剂盒) as a potential prognostic marker in glioblastoma
Suggest that CD44-positivity might be a candidate tumor stem cell marker in intrahepatic cholangiocarcinoma and a prognostic indicator.
Mechanistically, CD44v interacts with and stabilizes xCT (显示 SLC7A11 ELISA试剂盒) and thereby promotes the uptake of cysteine for glutathione synthesis and stimulates side-population cell enrichment.
These tumor samples express CD44 protein at low rather than high levels. There is no correlation between CLDN3 (显示 CLDN3 ELISA试剂盒) gene expression and protein expression in these CPTAC samples; hence, the claudin-low subtype defined by gene expression is not the same group of tumors as that defined by low expression of CLDN3 (显示 CLDN3 ELISA试剂盒) protein.
this study shows that genkwadaphnin promotes leukocyte migration by increasing CD44 expression via PKD1 (显示 PKD1 ELISA试剂盒)/NF-kappaB (显示 NFKB1 ELISA试剂盒) signaling pathway
High CD44 expression is associated with high grade glioma.
CNS disease was associated with enhanced expression of cytoplasmic and membranous ITGA10 and nuclear PTEN (P < 0.0005, P = 0.002, P = 0.024, respectively). sCNSL presented decreased membranous CD44 and nuclear and cytoplasmic cadherin-11 expressions (P = 0.001, P = 0.006, P = 0.048, respectively). In PCNSL lactoferrin (显示 LTF ELISA试剂盒) expression was upregulated (P < 0.0005).
In clinical specimens of breast cancer, authors established that the expression of CD44s and HAS2 (显示 HAS2 ELISA试剂盒) was positively correlated. Results establish a positive feedback mechanism that sustains PI3K (显示 PIK3CA ELISA试剂盒)/Akt (显示 AKT1 ELISA试剂盒) signaling in tumor cells, further illuminating the nearly universal role of this pathway in cancer cell survival.
In regulation of tumour cells with high CD44 expression.
ZEB1 (显示 ZEB1 ELISA试剂盒)-induced epithelial-to-mesenchymal transition and associated molecular changes in ESRP1 (显示 ESRP1 ELISA试剂盒) and CD44 contribute to early pathogenesis and metastatic potential in established lung cancer
CD44 knock-down in bovine and human chondrocytes results in release of bound HYAL2 (显示 HYAL2 ELISA试剂盒).
release of the CD44 intracellular domain into the cytoplasm of cells such as chondrocytes exerts a competitive or dominant-negative effect on the function of full-length CD44.
CD44 fragmentation, consistent with a signature pattern reported for sequential metalloproteinase/gamma-secretase cleavage of CD44, is a common metabolic feature of chondrocytes that have undergone dedifferentiation in vitro
determined the effects of Mycobacterium-induced proliferation and apoptosis on CD25 (显示 IL2RA ELISA试剂盒), CD44, and CD62L (显示 SELL ELISA试剂盒) expression on peripheral blood T-cell subsets from M. bovis-infected cattle.
detection of CD44 in the bovine oviductal epithelium
Oligosaccharides of hyaluronan induce angiogenesis through distinct CD44 and RHAMM (显示 HMMR ELISA试剂盒)-mediated signalling pathways involving Cdc2 (显示 CDK1 ELISA试剂盒) and gamma-adducin (显示 ADD3 ELISA试剂盒).
The novel finding that TSP-1 (显示 THBS1 ELISA试剂盒)-induced migration is dependent on the CD44 receptor links 2 pathways thought to be disparate (ie, TSP-1 (显示 THBS1 ELISA试剂盒) and HyA (显示 KDM5D ELISA试剂盒)).
An important role for the Hyaluronan-CD44 signaling pathway in reproductive function and inflammation.
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.
, GP90 lymphocyte homing/adhesion receptor
, extracellular matrix receptor III
, hermes antigen
, hyaluronate receptor
, lymphocyte antigen 24
, phagocytic glycoprotein 1
, phagocytic glycoprotein I
, CD44 antigen
, Cell surface glycoprotein CD44 (hyaluronate binding protein)
, Hermes antigen
, cell surface glycoprotein CD44
, chondroitin sulfate proteoglycan 8
, hematopoietic cell E- and L-selectin ligand
, heparan sulfate proteoglycan
, homing function and Indian blood group system
, extracellular matrix receptor-III
, CD44-like protein
, lymphocyte surface antigen precursor CD44
, syndecan 4 (amphiglycan, ryudocan)