anti-UCHL1 (UCHL1) 抗体产品概述

Full name:
anti-Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) 抗体 (UCHL1)
在www.antibodies-online.cn可供623 Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) 抗体的35不同的供货商。 再加上,我们可以发UCHL1 蛋白 (41)UCHL1 试剂盒 (26)和数多这个蛋白质的别的产品。 总共706 UCHL1产品已列进来了。
别名:
AW822034, C88048, cb358, gad, MGC132191, PARK5, PGP9.5, PGP 9.5, PGP95, R75593, Uch-L1, UCHL-1, uchl1, wu:fc55h08

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  1. Cow (Bovine) Monoclonal UCHL1 Primary Antibody for ELISA, ICC - ABIN269361 : Ständer, Schmelz, Metze, Luger, Rukwied: Distribution of cannabinoid receptor 1 (CB1) and 2 (CB2) on sensory nerve fibers and adnexal structures in human skin. in Journal of dermatological science 2005 (PubMed)
    Show all 8 references for 269361

  2. Human Polyclonal UCHL1 Primary Antibody for EIA, IHC (p) - ABIN357509 : Maraganore, de Andrade, Lesnick, Farrer, Bower, Hardy, Rocca: Complex interactions in Parkinson's disease: a two-phased approach. in Movement disorders : official journal of the Movement Disorder Society 2003 (PubMed)
    Show all 5 references for 357509

  3. Human Monoclonal UCHL1 Primary Antibody for WB - ABIN1882287 : Boudreaux, Maiti, Davies, Das: Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 4 references for 1882287

  4. Human Polyclonal UCHL1 Primary Antibody for IF (p), IHC (p) - ABIN704396 : Zheng, Zhu, Mu, Wu, Song, Zhai, Peng, Li, Hua: CD49f promotes proliferation of male dairy goat germline stem cells. in Cell proliferation 2016 (PubMed)
    Show all 4 references for 704396

  5. Human Polyclonal UCHL1 Primary Antibody for ICC, IF - ABIN152827 : Zheng, Begum, Zhang, Fleming, Masumura, Zhang, Smith, Darlington: Increased BrdU incorporation reflecting DNA repair, neuronal de-differentiation or possible neurogenesis in the adult cochlear nucleus following bilateral cochlear lesions in the rat. in Experimental brain research 2011 (PubMed)
    Show all 2 references for 152827

  6. Human Polyclonal UCHL1 Primary Antibody for FACS, IF - ABIN388868 : Caballero, Resto, Patturajan, Meerzaman, Guo, Engles, Yochem, Ratovitski, Sidransky, Jen: Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1). in Oncogene 2002 (PubMed)
    Show all 2 references for 388868

  7. Human Polyclonal UCHL1 Primary Antibody for IF, IHC (p) - ABIN388870 : Saigoh, Wang, Suh, Yamanishi, Sakai, Kiyosawa, Harada, Ichihara, Wakana, Kikuchi, Wada: Intragenic deletion in the gene encoding ubiquitin carboxy-terminal hydrolase in gad mice. in Nature genetics 1999 (PubMed)
    Show all 2 references for 388870

  8. Human Monoclonal UCHL1 Primary Antibody for IHC (p) - ABIN180669 : Wilkinson, Lee, Deshpande, Duerksen-Hughes, Boss, Pohl: The neuron-specific protein PGP 9.5 is a ubiquitin carboxyl-terminal hydrolase. in Science (New York, N.Y.) 1989 (PubMed)
    Show all 2 references for 180669

  9. Cow (Bovine) Polyclonal UCHL1 Primary Antibody for EIA, WB - ABIN499139 : Wu, Chen, Chen, Chao, Ro, Fung, Hsiao, Hu, Lee-Chen: Ubiquitin specific proteases USP24 and USP40 and ubiquitin thiolesterase UCHL1 polymorphisms have synergic effect on the risk of Parkinson's disease among Taiwanese. in Clinica chimica acta; international journal of clinical chemistry 2010 (PubMed)

更多抗UCHL1的相互作用对抗体

Mouse (Murine) Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. The UCHL1 may play a role in myogenesis by promoting myoblast proliferation and inhibiting differentiation.

  2. our study provides novel insights into the mechanisms of UCH-L1-mediated neurobiological functions and suggests that ubiquitination is an important regulatory signal for TrkB (显示 NTRK2 抗体)

  3. Effects of Ubiquitin C-Terminal Hydrolase L1 (UCH-L1) inhibition on sperm incorporation and cortical tension in mouse eggs.

  4. The neuronal marker UCH-L1 is induced in, and specifically augments the oncogene (显示 RAB1A 抗体)-induced transformation of, germinal center B cells.

  5. Pharmacological inhibition of UCHL1 exacerbates rather than ameliorates disease symptoms in a mouse model of SMA (显示 SMN1 抗体). Thus, pharmacological inhibition of UCHL1 is not a viable therapeutic target for SMA (显示 SMN1 抗体).

  6. Parkin (显示 PARK2 抗体) mediates K63-linked polyubiquitination of UCH-L1 in cooperation with the Ubc13 (显示 UBE2N 抗体)/Uev1a E2 ubiquitin-conjugating enzyme (显示 UBE2L6 抗体) complex and promotes UCH-L1 degradation by the autophagy-lysosome pathway.

  7. defective UCHL1 function may be an early contributor to vulnerability of pancreatic beta-cells for protein misfolding and proteotoxicity, hallmark defects in islets of T2DM

  8. UCH-L1 facilitates PDGF (显示 PDGFA 抗体)-BB-induced suppression of autophagic degradation of p21WAF1/Cip1 proteins in cardiac fibroblasts

  9. UCHL1 upregulation in ACTN4 (显示 ACTN4 抗体)-associated FSGS (显示 ACTN4 抗体).

  10. downregulated miR (显示 MLXIP 抗体)-181b induces neuroprotection against ischemic injury through negatively regulating HSPA5 (显示 HSPA5 抗体) and UCHL1 protein levels

Human Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. Aberrant expression of UCHL1 in pediatric high-grade gliomas may promote cell invasion, transformation, and self-renewal properties, at least in part, by modulating Wnt (显示 WNT2 抗体)/Beta catenin (显示 CTNNB1 抗体) activity

  2. Suppression of MITF (显示 MITF 抗体) activity by UCHL1 via protein degradation might aid in the development of new therapeutic approaches for melanoma or dyspigmentation disorders.

  3. Overexpression of UCH-L1 in MCF7 cells up-regulated MDR1 (显示 TBC1D9 抗体), CD147, MMP2 (显示 MMP2 抗体), and MMP9 (显示 MMP9 抗体), which conferred multidrug resistance and promoted migration/invasion.

  4. This study demonstrated that UCH-L1 was detectible within 1 hour of injury and rose rapidly and peaked at 8 hours after injury and declined rapidly over 48 hours.

  5. This study establishes the importance of UCHL1 in neurodegeneration, provides new mechanistic insight about ubiquitin processing, and underlines the complexity of the different roles of UCHL1

  6. TGF-beta1 (显示 TGFB1 抗体) can promote PGP9.5 expression in Cancer associated fibroblasts to facilitate the growth of cancer cells.

  7. PGP9.5 is also expressed in benign fibroblastic lesions

  8. cytoplasmic accumulation of P53 (显示 TP53 抗体) was strongly associated with the unmethylated UCHL1 profile (P = 0.006), supporting the relationship between these two proteins in sporadic colorectal cancer

  9. UCHL1 has a role in Alzheimer Disease [review]

  10. UCHL1 expression is highly upregulated upon hepatic stellate cell (HSC (显示 FUT1 抗体)) activation and is involved in the regulation of HSC (显示 FUT1 抗体) proliferation

Cow (Bovine) Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. These data indicate that antipolyspermy defense in bovine oocytes may rely on UCHL1-controlled functioning of These data indicate that antipolyspermy defense in bovine oocytes may rely on UCHL1-controlled functioning of cortical granules.

Pig (Porcine) Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. The elevation in UCH-L1 concentration is consistent with the severity of neural apoptosis following DHCA.

  2. Data report that ubiquitin carboxy-terminal hydrolase 1 is expressed in spermatogonia located at the basement membrane of seminiferous tubules at high and low levels, but not in differentiated germ cells distant from the BM.

Horse (Equine) Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1) interaction partners

  1. There was no difference in enteric neuronal density and distribution in the groups of animals with intestinal disease compared with those without, apart from two (out of 28) horses with intestinal disease that showed reduction in PGP 9.5 immunoreactivity.

UCHL1 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.

Alternative names and synonyms associated with UCHL1

  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (uchl1) 抗体
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (UCHL1) 抗体
  • Ubiquitin carboxyl-terminal hydrolase isozyme L1 (uchl1) 抗体
  • ubiquitin carboxyl-terminal esterase L1 (LOC100304750) 抗体
  • ubiquitin carboxyl-terminal esterase L1 (LOC100348287) 抗体
  • ubiquitin carboxyl-terminal esterase L1 (LOC100357806) 抗体
  • ubiquitin carboxy-terminal hydrolase L1 (Uchl1) 抗体
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (Uchl1) 抗体
  • AW822034 抗体
  • C88048 抗体
  • cb358 抗体
  • gad 抗体
  • MGC132191 抗体
  • PARK5 抗体
  • PGP9.5 抗体
  • PGP 9.5 抗体
  • PGP95 抗体
  • R75593 抗体
  • Uch-L1 抗体
  • UCHL-1 抗体
  • uchl1 抗体
  • wu:fc55h08 抗体

Protein level used designations for UCHL1

ubiquitin carboxyl-terminal hydrolase isozyme L1 , ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) , ubiquitin carboxyl-terminal esterase L1 , gracile axonal dystrophy , neuron cytoplasmic protein 9.5 , protein gene product 9.5 , ubiquitin thioesterase L1 , ubiquitin C-terminal hydrolase , PGP 9.5 , PGP9.5 , UCH-L1 , ubiquitin carboxy-terminal hydrolase L1 , ubiquitin C-terminal hydrolase-L1 , ubiquitin carboxyl-terminal hydrolase L1 , ubiquitin thiolesterase L1

GENE ID SPECIES
325119 Danio rerio
461185 Pan troglodytes
479098 Canis lupus familiaris
751589 Taeniopygia guttata
770302 Gallus gallus
496780 Xenopus (Silurana) tropicalis
735204 Xenopus laevis
100196868 Salmo salar
100304750 Ictalurus punctatus
100348287 Oryctolagus cuniculus
100357806 Oryctolagus cuniculus
22223 Mus musculus
7345 Homo sapiens
29545 Rattus norvegicus
514394 Bos taurus
100714582 Cavia porcellus
396637 Sus scrofa
100033838 Equus caballus
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