anti-RICTOR (RICTOR) 抗体产品概述

Full name:
anti-RPTOR Independent Companion of MTOR, Complex 2 抗体 (RICTOR)
在www.antibodies-online.cn可供193 RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) 抗体的22不同的供货商。 再加上,我们可以发RICTOR 试剂盒 (5)和数多这个蛋白质的别的产品。 总共209 RICTOR产品已列进来了。
别名:
4921505C17Rik, 6030405M08Rik, AVO3, AW492497, D530039E11Rik, Fyb, mAVO3, PIA
列出全部抗体 基因 基因ID UniProt
RICTOR 253260 Q6R327
RICTOR 78757 Q6QI06
RICTOR 310131  

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  1. Human Polyclonal RICTOR Primary Antibody for IP, WB - ABIN152042 : Hresko, Mueckler: mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. in The Journal of biological chemistry 2005 (PubMed)
    Show all 33 references for 152042

  2. Human Polyclonal RICTOR Primary Antibody for FACS, ICC - ABIN152043 : Jindra, Jin, Rozengurt, Reed: HLA class I antibody-mediated endothelial cell proliferation via the mTOR pathway. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 17 references for 152043

  3. Human Polyclonal RICTOR Primary Antibody for EIA, IHC (p) - ABIN359477 : Jacinto, Facchinetti, Liu, Soto, Wei, Jung, Huang, Qin, Su: SIN1/MIP1 maintains rictor-mTOR complex integrity and regulates Akt phosphorylation and substrate specificity. in Cell 2006 (PubMed)
    Show all 4 references for 359477

  4. Human Polyclonal RICTOR Primary Antibody for EIA, IHC (p) - ABIN359480 : Pearce, Huang, Boudeau, Paw?owski, Wullschleger, Deak, Ibrahim, Gourlay, Magnuson, Alessi: Identification of Protor as a novel Rictor-binding component of mTOR complex-2. in The Biochemical journal 2007 (PubMed)
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  5. Human Polyclonal RICTOR Primary Antibody for IHC, ELISA - ABIN185390 : Sarbassov, Ali, Kim, Guertin, Latek, Erdjument-Bromage, Tempst, Sabatini: Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. in Current biology : CB 2004 (PubMed)
    Show all 2 references for 185390

  6. Human Monoclonal RICTOR Primary Antibody for ELISA, FACS - ABIN4350528 : Loganathan, Kandala, Gupta, Srivastava: Inhibition of EGFR-AKT axis results in the suppression of ovarian tumors in vitro and in preclinical mouse model. in PLoS ONE 2012 (PubMed)
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  7. Human Polyclonal RICTOR Primary Antibody for IHC (p), WB - ABIN391384 : Gao, Wu, Spencer, Johnson, Bazer et al.: Select nutrients in the ovine uterine lumen. VI. Expression of FK506-binding protein 12-rapamycin complex-associated protein 1 (FRAP1) and regulators and effectors of mTORC1 and mTORC2 complexes in ... in Biology of reproduction 2009 (PubMed)
    Show all 2 references for 391384

  8. Human Monoclonal RICTOR Primary Antibody for ICC, FACS - ABIN969382 : Yang, Inoki, Ikenoue, Guan: Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. in Genes & development 2006 (PubMed)

更多抗RICTOR的相互作用对抗体

Human RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) interaction partners

  1. miR (显示 MLXIP 抗体)-153 downregulation could be one important reason of Rictor upregulation and mTORC2 (显示 CRTC2 抗体) over-activation in glioma cells. Further, miR (显示 MLXIP 抗体)-153-induced anti-glioma cell activity is possibly via downregulating Rictor.

  2. These results point to an increase in total and phosphorylated Akt (显示 AKT1 抗体) in high-grade gliomas and to a possible role of RICTOR in proliferations of high-grade glioblastomas cells.

  3. Hgh mTOR (显示 FRAP1 抗体) activity and Rictor overexpression could be markers of a bad prognosis. Combined phosphoprotein and Rictor/Raptor (显示 RPTOR 抗体) expression evaluation revealed even stronger statistical correlation with prognosis.

  4. In this study we began by validating the expression of four main mTOR (显示 FRAP1 抗体) pathway components, mTOR (显示 FRAP1 抗体), DEPTOR (显示 DEPTOR 抗体), rictor and raptor (显示 RPTOR 抗体), at gene and protein level in in vitro models of endometrioid (MDAH2774) and clear cell (SKOV3) ovarian cancer

  5. Based on univariate and multivariate Cox (显示 COX8A 抗体) proportional hazards regression analysis, RICTOR-positive expression, AJCC staging III or IV and nodal metastasis are prognostic factors and the former two are independent risk factors for esophageal squamous cell carcinoma.

  6. Taken together, our results suggest that the proinflammatory cytokine TNFalpha (显示 TNF 抗体) promotes the expression of Rictor through the NF-kappaB (显示 NFKB1 抗体) pathway in renal cell carcinoma (显示 MOK 抗体).

  7. RICTOR amplification may define a novel and unique molecular subset of patients with lung cancer who may benefit from treatment with mTORC1/2 inhibitors.

  8. Data show that rapamycin-insensitive companion of mTOR protein (RICTOR) plays a central role in phosphatidylinositol 3-kinase (PI3K (显示 PIK3CA 抗体))/proto-oncogene (显示 RAB1A 抗体) protein c (显示 PROC 抗体)-akt (AKT (显示 AKT1 抗体)) pathway in melanocytes and its deregulation could be involved in melanoma development.

  9. Mdm20 (显示 NAA25 抗体) acts as a novel regulator of Rictor, thereby controlling mTORC2 (显示 CRTC2 抗体) activity, and leading to the activation of PKCalphaS657 and FoxO1 (显示 FOXO1 抗体).

  10. RICTOR/MTORC2 (显示 CRTC2 抗体)-AKT (显示 AKT1 抗体) can integrate convergent hormonal and metabolic signals to provide coordinated and sensitive regulation of hepatic FOXO1 (显示 FOXO1 抗体)-target gene expression.

Mouse (Murine) RPTOR Independent Companion of MTOR, Complex 2 (RICTOR) interaction partners

  1. our present findings highlighted a pivotal regulatory axis of Rictor-FoxO3a (显示 FOXO3 抗体) in maintaining quiescence and the stemness of LSCs.

  2. These findings reveal a novel functional pathway important for age-related bone loss and support for miR (显示 MLXIP 抗体)-218 and Rictor as potential targets for therapeutic intervention for age-related osteoporosis treatment.

  3. this study shows that Rictor is required for NKT (显示 CTSL1 抗体)-17 cell development and normal iNKT-cell cytolytic function

  4. data suggest that Rictor/mTORC2 (显示 CRTC2 抗体) controls an amino acid-sensitive checkpoint that allows T cells to determine whether the microenvironment contains sufficient resources for daughter cell generation.

  5. Loss of DNMT3B (显示 DNMT3B 抗体) results in hypomethylation of the miR (显示 MLXIP 抗体)-196b promoter and increased miR (显示 MLXIP 抗体)-196b expression, which directly targets the mTORC2 (显示 CRTC2 抗体) component Rictor.

  6. Rictor in the limb mesenchymal lineage is required for the normal response to the anti-sclerostin (显示 SOST 抗体) therapy in both bone formation and resorption.

  7. Low RICTOR expression was detected in quiescent, confluent mouse aortic endothelial cells, whereas high doses of FGF2 (显示 FGF2 抗体) induced high RICTOR expression that was associated with strong mTORC2 (显示 CRTC2 抗体)-specific protein kinase (显示 CDK7 抗体) Ca and AKT (显示 AKT1 抗体) phosphorylation

  8. analysis of mTORC2 (显示 CRTC2 抗体) components mTOR (显示 FRAP1 抗体), Rictor and mSin1 reveals diurnal variation in mouse perivascular adipose tissue

  9. Adipose tissue mTORC2 (显示 CRTC2 抗体) regulates via Rictor ChREBP (显示 MLXIPL 抗体)-driven de novo lipogenesis and hepatic glucose metabolism.

  10. Rictor is essential for the generation of type II IFN-dependent antiviral and antiproliferative responses and that it controls the generation of type II IFN-suppressive effects on normal and malignant hematopoiesis

RICTOR 抗原简介

Antigen Summary

RICTOR and MTOR (FRAP1\; MIM 601231) are components of a protein complex that integrates nutrient- and growth factor-derived signals to regulate cell growth (Sarbassov et al., 2004

Alternative names and synonyms associated with RICTOR

  • RPTOR independent companion of MTOR, complex 2 (RICTOR) 抗体
  • rapamycin-insensitive companion of mTOR (LOC100357138) 抗体
  • RPTOR independent companion of MTOR, complex 2 (Rictor) 抗体
  • 4921505C17Rik 抗体
  • 6030405M08Rik 抗体
  • AVO3 抗体
  • AW492497 抗体
  • D530039E11Rik 抗体
  • Fyb 抗体
  • mAVO3 抗体
  • PIA 抗体

Protein level used designations for RICTOR

rapamycin-insensitive companion of mTOR , AVO3 homolog , TORC2-specific protein AVO3 , hAVO3 , pianissimo , mAVO3 , protein pianissimo , FYN binding protein , rapamycin insensitive companion of mTOR

GENE ID SPECIES
694915 Macaca mulatta
100357138 Oryctolagus cuniculus
253260 Homo sapiens
78757 Mus musculus
479356 Canis lupus familiaris
310131 Rattus norvegicus
527459 Bos taurus
100519575 Sus scrofa
100715888 Cavia porcellus
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