anti-大鼠 ERN1 抗体 for Enzyme Immunoassay

Recommended ERN1 Antibody (supplied by: Log in to see )

抗原
Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) 抗体
  • 9030414B18Rik
  • AI225830
  • C85377
  • Ire1a
  • Ire1alpha
  • Ire1p
  • Ern1
  • Ire1
  • Ire1b
  • IRE1
  • IRE1P
  • IRE1a
  • hIRE1p
  • RGD1559716
  • endoplasmic reticulum (ER) to nucleus signalling 1
  • endoplasmic reticulum (ER) to nucleus signalling 2
  • endoplasmic reticulum to nucleus signaling 1
  • endoplasmic reticulum to nucleus signalling 1
  • Ern1
  • Ern2
  • ERN1
  • LOC100357346
抗原表位
C-Term
32
20
19
18
15
15
15
15
14
10
8
8
8
8
7
6
4
4
2
1
1
1
1
适用
人, 小鼠, 大鼠
190
107
74
13
13
13
12
12
2
1
1
宿主

158
32
16
3
克隆类型
多克隆
标记
This ERN1 antibody is un-conjugated
13
12
11
6
6
6
5
5
5
5
5
3
3
3
2
2
2
2
2
2
2
2
2
应用范围
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
176
97
44
34
33
31
26
14
8
4
4
1
1
Supplier
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产品编号 ABIN5554901
3,587.17 ¥
(含税, 含运费)
来自4A Biotech Co.,Ltd.(本地经销商)
获取报价
中国 北京 101111
No. 88 KeChuang 6th Street
Room 801-803
Beijing Economic Technological Development Area
4A Biotech Co.,Ltd.
Tel 400-7060-959
传真 +86 10 56315212-8813
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5554902 EIA IF WB Rabbit IgG N-Term Log in to see Polyclonal

Similar anti-ERN1 抗体

应用范围 / 适用 大鼠 小鼠
ELISA 27 抗体 39 抗体
Enzyme Immunoassay (EIA) 2 抗体 2 抗体
Immunocytochemistry (ICC) 33 抗体 33 抗体
Immunofluorescence (IF) 25 抗体 25 抗体
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 13 抗体 13 抗体
Immunohistochemistry (IHC) 16 抗体 16 抗体
Immunohistochemistry (Frozen Sections) (IHC (fro)) 14 抗体 14 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 29 抗体 29 抗体
Immunoprecipitation (IP) 7 抗体 7 抗体
Western Blotting (WB) 61 抗体 93 抗体

General

抗原 Endoplasmic Reticulum To Nucleus Signaling 1 (ERN1) 抗体
抗原表位 C-Term
(32), (20), (19), (18), (15), (15), (15), (15), (14), (10), (8), (8), (8), (8), (7), (6), (4), (4), (2), (1), (1), (1), (1)
适用 人, 小鼠, 大鼠
(190), (107), (74), (13), (13), (13), (12), (12), (2), (1), (1)
宿主
(158), (32), (16), (3)
克隆类型
多克隆
标记 This ERN1 antibody is un-conjugated
(13), (12), (11), (6), (6), (6), (5), (5), (5), (5), (5), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2)
应用范围 Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(176), (97), (44), (34), (33), (31), (26), (14), (8), (4), (4), (1), (1)
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ERN1抗体详情

ERN1目标详情 使用细节 贮存及处理 图像
特异性 IRE1p antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human IRE1p.
纯化方法 Affinity Chromatography purified via peptide column
免疫原 16 amino acid synthetic peptide from near the carboxy terminus of Human IRE1p
亚型 IgG

ERN1目标详情

ERN1抗体详情 使用细节 贮存及处理 图像 回页首
抗原
别名 ERN1 / IRE1 (ERN1 Antibody 摘要)
背景 Accumulation of malfolded proteins in the endoplasmic reticulum (ER) activates the unfolded protein response (UPR) and the upregulation of the ER molecular chaperones GRP78 and GRP 94 (1,2). These proteins are normally bound to ER transmembrane proteins such as IRE1p and ATF6 (3,4) but ER stress causes their dissociation. This allows IRE1p, a serine-threonine protein kinase to transduce the unfolded protein signal from the ER to the nucleus. IRE1p also has an endoribonuclease activity that is required to splice X-box binding protein (XBP1) mRNA converting it to a potent UPR transcriptional activation (5). Depletion of IRE1p through the expression of a dominant negative form of IRE1p has no effect on transfected cells, but cell death via apoptosis occurs under stress conditions that cause unfolded proteins to accumulate in the ER (6). Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.Synonyms: Endoplasmic reticulum-to-nucleus signaling 1, IRE1a, IRE1p, Inositol-requiring protein 1, Ire1-alpha, Serine/threonine-protein kinase/endoribonuclease IRE1
基因ID 2081
UniProt O75460
途径 ER-Nucleus Signaling

使用细节

ERN1抗体详情 ERN1目标详情 贮存及处理 图像 回页首
应用备注 ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
限制 仅限研究用

贮存及处理

ERN1抗体详情 ERN1目标详情 使用细节 图像 回页首
浓度 1.0 mg/mL
缓冲液 PBS containing 0.02 % Sodium Azide
储存液 Sodium azide
注意事项 This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项 Avoid repeated freezing and thawing.
储存条件 4 °C/-20 °C
储存方法 Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.