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VAV1 蛋白

(Vav 1 Oncogene (VAV1))
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012].
VAV1 Protein (AA 189-565) (His tag) VAV1 Protein (AA 189-565) (His tag) VAV1 Protein (AA 189-565) (His tag) (ABIN7125706)

VAV1 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA

VAV1 Protein (AA 681-790) (GST tag) VAV1 Protein (AA 681-790) (GST tag) VAV1 Protein (AA 681-790) (GST tag) (ABIN1324929)

VAV1 宿主: 人 宿主: 小麦胚 Recombinant WB, ELISA, AA, AP

VAV1 Protein (AA 1-845) (His tag) VAV1 Protein (AA 1-845) (His tag) VAV1 Protein (AA 1-845) (His tag) (ABIN3075384)

Crystallography grade VAV1 宿主: 人 宿主: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys

VAV1 蛋白 by Grade

Find VAV1 蛋白 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

VAV1 蛋白 by Origin

Find VAV1 蛋白 for a variety of species such as anti-Human VAV1, anti-Mouse VAV1. The species listed below are among those available. Click on a link to go to the corresponding products.

VAV1 蛋白 by Source

Here you will find VAV1 蛋白 proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

VAV1 蛋白 by 蛋白类型

Here you can find VAV1 蛋白 proteins categorized by available protein types. Additional protein types can be located using our search function.

VAV1 蛋白 by 应用范围

Find VAV1 蛋白 validated for a specific application such as WB, ELISA, SDS, Imm. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular VAV1 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7125706
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1324929
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3075384
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
  • (1)
Cat. No. ABIN2735197
Quantity 20 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418038
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7417078
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Baculovirus infected Insect Cells, Insect cells (Sf9)
Validations
Cat. No. ABIN6700862
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our VAV1 蛋白

Mahankali, Peng, Henkels, Dinauer, Gomez-Cambronero: "Phospholipase D2 (PLD2) is a guanine nucleotide exchange factor (GEF) for the GTPase Rac2." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 49, pp. 19617-22, (2011) (PubMed).

Aliases for VAV1 蛋白

vav guanine nucleotide exchange factor 1 (VAV1) 蛋白
vav guanine nucleotide exchange factor 1 (Vav1) 蛋白
vav 1 oncogene (Vav1) 蛋白
vav guanine nucleotide exchange factor 1 L homeolog (vav1.L) 蛋白
VAV 蛋白
Vav 蛋白
vav-T 蛋白
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