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The G-102A polymorphism in STAM2 is significantly associated with withers height, heart girth, cannon circumference, chest width, and hip height in Wuchuan Black cattle
SLBP (显示 SLBP ELISA试剂盒) is a potentially important cellular regulator of HIV-1, thereby establishing a link between histone metabolism, inflammation, and HIV-1 infection
showed that inhibiting the SLBP (显示 SLBP ELISA试剂盒) mRNA and protein levels were rescued by epigenetic modifiers suggesting that nickel's effects on SLBP (显示 SLBP ELISA试剂盒) may be mediated via epigenetic mechanisms
Cyclin F (显示 CCNF ELISA试剂盒)-mediated degradation of SLBP (显示 SLBP ELISA试剂盒) limits H2A.X (显示 H2AFX ELISA试剂盒) accumulation and apoptosis upon genotoxic stress in G2 cell cycle checkpoint.
CRL4(WDR23 (显示 DCAF11 ELISA试剂盒)) is required for efficient histone mRNA 3' end processing to produce mature histone mRNAs for translation. CRL4(WDR23 (显示 DCAF11 ELISA试剂盒)) binds and ubiquitylates SLBP (显示 SLBP ELISA试剂盒) in vitro and in vivo, and this modification activates SLBP (显示 SLBP ELISA试剂盒) function in histone mRNA 3' end processing without affecting its protein levels.
FEM1 proteins are ancient regulators of Stem-Loop Binding Protein (显示 SLBP ELISA试剂盒).
CRL4-DCAF11 (显示 DCAF11 ELISA试剂盒) mediates the degradation of SLBP (显示 SLBP ELISA试剂盒) at the end of S phase and this degradation is essential for the viability of cells.
The authors propose a structural organization where the AMSH (显示 STAMBP ELISA试剂盒)-SH3 binding motif interacts with the STAM2-SH3 domain (显示 ITSN1 ELISA试剂盒) and contributes to the correct positioning of AMSH (显示 STAMBP ELISA试剂盒) prior to polyubiquitin (显示 UBB ELISA试剂盒) chains' cleavage.
The VHS domain of STAM2 directs AMSH to cleave longer Lys63-linked ubiquitin chains
homologous domain of human Bro1 (显示 HMGCR ELISA试剂盒) domain-containing proteins, Alix (显示 PDCD6IP ELISA试剂盒) and Brox, binds CHMP4B (显示 CHMP4A ELISA试剂盒) but not STAM2, despite their high structural similarity
arsenic, a carcinogenic metal, decreases cellular levels of SLBP (显示 SLBP ELISA试剂盒) by inducing its proteasomal degradation and inhibiting SLBP (显示 SLBP ELISA试剂盒) transcription via epigenetic mechanisms
Stam2 is expressed in the nervous tissue, heart, digestive and endocrine system during embryo development.
These results demonstrate that the STAMs are indispensably involved in T-cell development and survival in the thymus through the prevention of apoptosis but are dispensable for the proximal signaling of TCR and cytokine receptors.
STAM (显示 STAM ELISA试剂盒) proteins function in a multivalent complex that sorts ubiquitinated proteins into the multivesicular body pathway.
SH3 domains of STAM2 and Grb2 (显示 GRB2 ELISA试剂盒) retain the moderate characteristics of recognizing their ligand proteins like other SH3 domains for signal protein (显示 KLK7 ELISA试剂盒) binding
This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
, signal transducing adapter molecule 2
, signal transducing adaptor molecule 2
, signal transducing adapter molecule 2-like
, HSE1 homolog
, Hrs-binding protein
, STAM-like protein containing SH3 and ITAM domains 2
, Hrs binding protein
, hrs-binding protein
, EAST protein
, epidermal growth factor receptor-associated protein with SH3 and TAM domain
, hairpin binding protein, histone
, histone RNA hairpin-binding protein
, histone binding protein
, histone stem-loop binding protein
, histone stem-loop-binding protein
, stem-loop (histone) binding protein