anti-SOX9 (SOX9) 抗体产品概述

Full name:
anti-SRY (Sex Determining Region Y)-Box 9 抗体 (SOX9)
在www.antibodies-online.cn可供208 SRY (Sex Determining Region Y)-Box 9 (SOX9) 抗体的24不同的供货商。 再加上,我们可以发SOX9 试剂盒 (34)SOX9 蛋白 (15)和数多这个蛋白质的别的产品。 总共268 SOX9产品已列进来了。
别名:
2010306G03Rik, AV220920, CMD1, CMPD1, LOC100227849, mKIAA4243, SOX-9, SOX9, SRA1

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  1. Human Polyclonal SOX9 Primary Antibody for IF (p), IHC (p) - ABIN754963 : Papaioannou, Mirzamohammadi, Lisse, Nishimori, Wein, Kobayashi: MicroRNA-140 provides robustness to the regulation of hypertrophic chondrocyte differentiation by the PTHrP-HDAC4 pathway. in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2014 (PubMed)
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  2. Human Monoclonal SOX9 Primary Antibody for IF, WB - ABIN394231 : Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010 (PubMed)
    Show all 5 references for 394231

  3. Human Monoclonal SOX9 Primary Antibody for EIA, IF - ABIN1109113 : Gordon, Tan, Benko, Fitzpatrick, Lyonnet, Farlie: Long-range regulation at the SOX9 locus in development and disease. in Journal of medical genetics 2009 (PubMed)
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  4. Cow (Bovine) Polyclonal SOX9 Primary Antibody for FACS, WB - ABIN2780338 : Vidal, Ortonne, Schedl: SOX9 expression is a general marker of basal cell carcinoma and adnexal-related neoplasms. in Journal of cutaneous pathology 2008 (PubMed)
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  5. Human Polyclonal SOX9 Primary Antibody for EIA, WB - ABIN356880 : Malki, Bibeau, Notarnicola, Roques, Berta, Poulat, Boizet-Bonhoure: Expression and biological role of the prostaglandin D synthase/SOX9 pathway in human ovarian cancer cells. in Cancer letters 2007 (PubMed)
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  6. Human Monoclonal SOX9 Primary Antibody for ICC, ELISA - ABIN969568 : Dupasquier, Abdel-Samad, Glazer, Bastide, Jay, Joubert, Cavaillès, Blache, Quittau-Prévostel: A new mechanism of SOX9 action to regulate PKCalpha expression in the intestine epithelium. in Journal of cell science 2009 (PubMed)
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  7. Human Polyclonal SOX9 Primary Antibody for EIA, IF - ABIN356879 : Passeron, Valencia, Bertolotto, Hoashi, Le Pape, Takahashi, Ballotti, Hearing: SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)
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  8. Cow (Bovine) Polyclonal SOX9 Primary Antibody for WB - ABIN2792587 : Furumatsu, Tsuda, Yoshida, Taniguchi, Ito, Hashimoto, Ito, Asahara: Sox9 and p300 cooperatively regulate chromatin-mediated transcription. in The Journal of biological chemistry 2005 (PubMed)

更多抗SOX9的相互作用对抗体

Human SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. These findings suggest that SOX9 may play an important role in tumor progression of Renal Cell Carcinoma (显示 MOK 抗体) and Bladder Cancer and it may be used as a biomarker of this malignancy.

  2. Loss of DDRGK1 decreases SOX9 expression and causes a human skeletal dysplasia.

  3. The expression of EVI1 (显示 MECOM 抗体) and SOX9 is associated with stem cell-like and metastasis signatures, and their depletion impairs the metastatic potential of breast cancer cells. These results establish the mechanistic link between resistance to mTOR (显示 FRAP1 抗体) inhibition and cancer metastatic potential, thus enhancing our understanding of mTOR (显示 FRAP1 抗体) targeting failure

  4. regulation of cancer stem cell via SLUG (显示 SNAI2 抗体)-SOX9 regulatory axis

  5. data indicate that SOX9 expression drives prostate cancer by reactivating the WNT (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling that mediates ductal morphogenesis in fetal prostate and define a subgroup of patients who would benefit from WNT (显示 WNT2 抗体)-targeted therapy.

  6. Low levels of SOX9 in primary stage II colon tumors predicts high risk of relapse.

  7. ELF3 (显示 ELF3 抗体) interacts directly with the HMG (显示 SSRP1 抗体) domain of Sox9. Importantly, overexpression of ELF3 (显示 ELF3 抗体) significantly decreased Sox9/CBP (显示 CREBBP 抗体)-dependent HAT (显示 MGEA5 抗体) activity.

  8. SOX9 is required for chondrogenesis: it secures chondrocyte lineage commitment, promotes cell survival, and transcriptionally activates the genes for many cartilage-specific structural components and regulatory factors.

  9. SOX9 is almost exclusively expressed by astrocytes in the adult brain except for ependymal cells and in the neurogenic regions, where SOX9 is also expressed by neural progenitor cells

  10. These findings indicate that chronic overexpression of Sox9 in the uterine epithelium can induce the development of endometrial hyperplastic lesions. Thus, SOX9 expression may be a factor in the formation of endometrial cancer.

Pig (Porcine) SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. data presented here demonstrate that the 18 bp indel in the porcine SOX9 5'-UTR (显示 UTS2R 抗体) is of functional importance and may therefore indeed be a causative variation in SOX9 associated traits

  2. HIF-1alpha (显示 HIF1A 抗体) activates Sox9 expression and enhances Sox9-mediated transcriptional activity.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 9 (SOX9) interaction partners

  1. Sox9 is positively regulated by mesenchymal Fgf10 (显示 FGF10 抗体), a process that requires active Erk (显示 EPHB2 抗体) signaling during salivary gland development

  2. TSC1 (显示 TSC1 抗体)/TSC2 (显示 TSC2 抗体) complex upregulation of OPN (显示 SPP1 抗体) expression is mediated by transcription factor SOX9 in an mTOR (显示 FRAP1 抗体)-independent manner. Moreover, ablation of OPN (显示 SPP1 抗体) by deficient TSC1 (显示 TSC1 抗体)/TSC2 (显示 TSC2 抗体) complex contributed to inactivation of AKT (显示 AKT1 抗体) in TSC (显示 SLC12A3 抗体) cells

  3. SOX9 is almost exclusively expressed by astrocytes in the adult brain except for ependymal cells and in the neurogenic regions, where SOX9 is also expressed by neural progenitor cells

  4. hese findings indicate that chronic overexpression of Sox9 in the uterine epithelium can induce the development of endometrial hyperplastic lesions. Thus, SOX9 expression may be a factor in the formation of endometrial cancer.

  5. The conditional ablation of Sox9 in the genital tubercle using Shh (显示 SHH 抗体)-Cre/+;Sox9(flox/flox) mice revealed no genital tubercle abnormalities, possibly due to compensation by similar Sox (显示 QSOX1 抗体) factors.

  6. The level of SOX9 protein in the kidneys of acute kidney injury-mice is reduced and correlates inversely with increased expression of microRNA miR (显示 MLXIP 抗体)-1247.

  7. Results show that SOX9, a key transcription factor involved in chondrogenesis, regulates Smpd3 (显示 SMPD3 抗体) expression in chondrogenic cells.

  8. These findings suggest a novel mechanism of action of SOX5 (显示 SOX5 抗体)/6; namely, the SOX9/5/6 combination enhances Col2a1 (显示 COL2A1 抗体) transcription through a novel enhancer in intron 6 together with the enhancer in intron 1.

  9. These findings illuminate a novel role for Stat3 (显示 STAT3 抗体) in chondrocytes during skeletal development through modulation of a critical factor, Sox9. Importantly, they further provide the first evidence for the modulation of a gene product other than Sox9 itself which is capable of modeling pathological aspects of CD and underscore a potentially valuable therapeutic target for patients with the disorder.

  10. Intact TES (显示 TES 抗体)/TESCO is required for directing appropriate Sox9 expression levels in the testis.

SOX9 抗原简介

Antigen Summary

The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.

Alternative names and synonyms associated with SOX9

  • SRY (sex determining region Y)-box 9 (SOX9) 抗体
  • SRY (sex determining region Y)-box 9 (LOC100227849) 抗体
  • SRY (sex determining region Y)-box 10 (SOX10) 抗体
  • SRY (sex determining region Y)-box 9 (Sox9) 抗体
  • SRY-box containing gene 9 (Sox9) 抗体
  • 2010306G03Rik 抗体
  • AV220920 抗体
  • CMD1 抗体
  • CMPD1 抗体
  • LOC100227849 抗体
  • mKIAA4243 抗体
  • SOX-9 抗体
  • SOX9 抗体
  • SRA1 抗体

Protein level used designations for SOX9

SRY (sex determining region Y)-box 9 , SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal) , transcription factor SOX-10 , SRY (sex-determining region Y)-box 9 protein , SRY-related HMG-box, gene 9 , transcription factor SOX-9 , SRY-box containing protein 9 , SRY-box containing gene 9 , transcription factor SOX9

GENE ID SPECIES
100452528 Pongo abelii
100227849 Taeniopygia guttata
353115 Bos taurus
6662 Homo sapiens
374148 Gallus gallus
403464 Canis lupus familiaris
140586 Rattus norvegicus
396840 Sus scrofa
450101 Pan troglodytes
574208 Macaca mulatta
20682 Mus musculus
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