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PTPN2 抗体

(Protein tyrosine Phosphatase, Non-Receptor Type 2 (PTPN2))
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Epidermal growth factor receptor and the adaptor protein Shc were reported to be substrates of this PTP, which suggested the roles in growth factor mediated cell signaling. Multiple alternatively spliced transcript variants encoding different isoforms have been found. Two highly related but distinctly processed pseudogenes that localize to chromosomes 1 and 13, respectively, have been reported. [provided by RefSeq, May 2011].
PTPN2 抗体  (AA 1-353) PTPN2 抗体  (AA 1-353) PTPN2 抗体 (AA 1-353) (ABIN3022585)

PTPN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

PTPN2 抗体  (AA 1-257) PTPN2 抗体  (AA 1-257) PTPN2 抗体 (AA 1-257) (ABIN7444958)

PTPN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

PTPN2 抗体  (AA 1-387) PTPN2 抗体  (AA 1-387) PTPN2 抗体 (AA 1-387) (ABIN519504)

PTPN2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

PTPN2 抗体 by 适用

Find PTPN2 抗体 for a variety of species such as anti-Human PTPN2, anti-Mouse PTPN2, anti-Rat PTPN2. The species listed below are among those available. Click on a link to go to the corresponding products.

PTPN2 抗体 by 应用范围

Find PTPN2 抗体 validated for a specific application such as WB, IHC, ELISA, IP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

PTPN2 抗体 by 抗体来源

Find PTPN2 抗体 with a specific 抗体来源. The 抗体来源 listed below are among those available. Click on a link to go to the corresponding products.

PTPN2 抗体 by 抗原表位

Find PTPN2 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

PTPN2 抗体 by 克隆形成能力

Find available monoclonal or polyclonal PTPN2 抗体. Click on a link to go to the corresponding products.

PTPN2 抗体 by 克隆

Find PTPN2 抗体 with a specific 克隆. The 克隆 listed below are among those available. Click on a link to go to the corresponding products.

PTPN2 抗体 by 标记

Find PTPN2 抗体 with a specific conjugate such as Biotin, APC, FITC. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular PTPN2 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IF
Validations
  • (8)
Cat. No. ABIN3022585
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7444958
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IP
Validations
  • (3)
Cat. No. ABIN519504
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF
Validations
  • (3)
Cat. No. ABIN7259775
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA
Validations
  • (2)
Cat. No. ABIN7192064
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (2)
Cat. No. ABIN6738161
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA
Validations
  • (2)
Cat. No. ABIN6264516
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Rat
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN3043447
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (1)
  • (2)
Cat. No. ABIN657234
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, IF, IC
Validations
  • (3)
Cat. No. ABIN7308244
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB
Validations
  • (1)
Cat. No. ABIN519503
Quantity 50 μg
Datasheet Datasheet

Application WB
Validations
  • (1)
Cat. No. ABIN205078
Quantity 100 μL
Datasheet Datasheet

Application WB
Validations
  • (2)
Cat. No. ABIN2782194
Quantity 100 μL
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN2782195
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA
Validations
Cat. No. ABIN6389415
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our PTPN2 抗体

Aradi, Kato, Filkova, Karouzakis, Klein, Scharl, Kolling, Michel, Gay, Buzas, Gay, Jüngel: "Protein Tyrosine Phosphatase Nonreceptor Type 2 (PTPN2), an Important Regulator of IL-6 Production in Rheumatoid Arthritis Synovial Fibroblasts." in: Arthritis & rheumatology (Hoboken, N.J.), (2015) (PubMed).

Doody, Bourdeau, Tremblay: "T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease." in: Immunological reviews, Vol. 228, Issue 1, pp. 325-41, (2009) (PubMed).

Bourdeau, Dubé, Heinonen, Théberge, Doody, Tremblay: "TC-PTP-deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-{gamma}." in: Blood, Vol. 109, Issue 10, pp. 4220-8, (2007) (PubMed).

Galic, Klingler-Hoffmann, Fodero-Tavoletti, Puryer, Meng, Tonks, Tiganis: "Regulation of insulin receptor signaling by the protein tyrosine phosphatase TCPTP." in: Molecular and cellular biology, Vol. 23, Issue 6, pp. 2096-108, (2003) (PubMed).

Dupuis, De Jesús Ibarra-Sánchez, Tremblay, Duplay: "Gr-1+ myeloid cells lacking T cell protein tyrosine phosphatase inhibit lymphocyte proliferation by an IFN-gamma- and nitric oxide-dependent mechanism." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 171, Issue 2, pp. 726-32, (2003) (PubMed).

ten Hoeve, de Jesus Ibarra-Sanchez, Fu, Zhu, Tremblay, David, Shuai: "Identification of a nuclear Stat1 protein tyrosine phosphatase." in: Molecular and cellular biology, Vol. 22, Issue 16, pp. 5662-8, (2002) (PubMed).

Aliases for PTPN2 抗体

protein tyrosine phosphatase, non-receptor type 2 (PTPN2) 抗体
protein tyrosine phosphatase, non-receptor type 2 (Ptpn2) 抗体
protein tyrosine phosphatase, non-receptor type 2 S homeolog (ptpn2.S) 抗体
protein tyrosine phosphatase, non-receptor type 2, b (ptpn2b) 抗体
protein tyrosine phosphatase, non-receptor type 2, a (ptpn2a) 抗体
protein tyrosine phosphatase, non-receptor type 2 L homeolog (ptpn2.L) 抗体
AI325124 抗体
cb806 抗体
hm:zeh1546 抗体
PTN2 抗体
ptn2 抗体
PTP-1B 抗体
ptpn2 抗体
ptpn2l 抗体
PTPT 抗体
Ptpt 抗体
ptpt 抗体
TC-PTP 抗体
tc-ptp 抗体
TCELLPTP 抗体
tcellptp 抗体
TCPTP 抗体
tcptp 抗体
wu:fc10h07 抗体
zgc:55339 抗体
zgc:63623 抗体
zgc:76973 抗体
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